GENOVESE, MASSIMO
GENOVESE, MASSIMO
Scienze Biomediche, Sperimentali e Cliniche 'Mario Serio'
A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity
2022 Sblano S.; Cerchia C.; Laghezza A.; Piemontese L.; Brunetti L.; Leuci R.; Gilardi F.; Thomas A.; Genovese M.; Santi A.; Tortorella P.; Paoli P.; Lavecchia A.; Loiodice F.
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition
2023 Laghezza A.; Cerchia C.; Genovese M.; Leuci R.; Pranzini E.; Santi A.; Brunetti L.; Piemontese L.; Tortorella P.; Biswas A.; Singh R.P.; Tambe S.; Ca S.; Pattnaik A.K.; Jayaprakash V.; Paoli P.; Lavecchia A.; Loiodice F.
Designed multiple ligands for the treatment of type 2 diabetes mellitus and its complications: Discovery of (5-arylidene-4-oxo-2-thioxothiazolidin-3-yl)alkanoic acids active as novel dual-targeted PTP1B/AKR1B1 inhibitors
2023 Maccari R.; Wolber G.; Genovese M.; Sardelli G.; Talagayev V.; Balestri F.; Luti S.; Santi A.; Moschini R.; Del Corso A.; Paoli P.; Ottana R.
Evidence of Insulin-Sensitizing and Mimetic Activity of the Sesquiterpene Quinone Avarone, a Protein Tyrosine Phosphatase 1B and Aldose Reductase Dual Targeting Agent from the Marine Sponge Dysidea avara
2023 Casertano M.; Genovese M.; Santi A.; Pranzini E.; Balestri F.; Piazza L.; Del Corso A.; Avunduk S.; Imperatore C.; Menna M.; Paoli P.
Identifying Human PTP1B Enzyme Inhibitors from Marine Natural Products: Perspectives for Developing of Novel Insulin-Mimetic Drugs
2022 Casertano M.; Genovese M.; Piazza L.; Balestri F.; Del Corso A.; Vito A.; Paoli P.; Santi A.; Imperatore C.; Menna M.
In search for multi-target ligands as potential agents for diabetes mellitus and its complications—a structure-activity relationship study on inhibitors of aldose reductase and protein tyrosine phosphatase 1b
2021 Rosaria Ottanà, Paolo Paoli, Mario Cappiello, Trung Ngoc Nguyen, Ilenia Adornato, Antonella Del Corso, Massimo Genovese, Ilaria Nesi, Roberta Moschini, Alexandra Naß, GerhardWolber and Rosanna Maccari,
Studying the trafficking of labeled trodusquemine and its application as nerve marker for light-sheet and expansion microscopy
2022 Claudia Capitini, Luca Pesce, Giulia Fani, Giacomo Mazzamuto, Massimo Genovese, Alessandra Franceschini, Paolo Paoli, Giuseppe Pieraccini, Michael Zasloff, Fabrizio Chiti, Francesco S Pavone, Martino Calamai
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity | 2022 | Sblano S.; Cerchia C.; Laghezza A.; Piemontese L.; Brunetti L.; Leuci R.; Gilardi F.; Thomas A.; Genovese M.; Santi A.; Tortorella P.; Paoli P.; Lavecchia A.; Loiodice F. | |
| A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition | 2023 | Laghezza A.; Cerchia C.; Genovese M.; Leuci R.; Pranzini E.; Santi A.; Brunetti L.; Piemontese L.; Tortorella P.; Biswas A.; Singh R.P.; Tambe S.; Ca S.; Pattnaik A.K.; Jayaprakash V.; Paoli P.; Lavecchia A.; Loiodice F. | |
| Designed multiple ligands for the treatment of type 2 diabetes mellitus and its complications: Discovery of (5-arylidene-4-oxo-2-thioxothiazolidin-3-yl)alkanoic acids active as novel dual-targeted PTP1B/AKR1B1 inhibitors | 2023 | Maccari R.; Wolber G.; Genovese M.; Sardelli G.; Talagayev V.; Balestri F.; Luti S.; Santi A.; Moschini R.; Del Corso A.; Paoli P.; Ottana R. | |
| Evidence of Insulin-Sensitizing and Mimetic Activity of the Sesquiterpene Quinone Avarone, a Protein Tyrosine Phosphatase 1B and Aldose Reductase Dual Targeting Agent from the Marine Sponge Dysidea avara | 2023 | Casertano M.; Genovese M.; Santi A.; Pranzini E.; Balestri F.; Piazza L.; Del Corso A.; Avunduk S.; Imperatore C.; Menna M.; Paoli P. | |
| Identifying Human PTP1B Enzyme Inhibitors from Marine Natural Products: Perspectives for Developing of Novel Insulin-Mimetic Drugs | 2022 | Casertano M.; Genovese M.; Piazza L.; Balestri F.; Del Corso A.; Vito A.; Paoli P.; Santi A.; Imperatore C.; Menna M. | |
| In search for multi-target ligands as potential agents for diabetes mellitus and its complications—a structure-activity relationship study on inhibitors of aldose reductase and protein tyrosine phosphatase 1b | 2021 | Rosaria Ottanà, Paolo Paoli, Mario Cappiello, Trung Ngoc Nguyen, Ilenia Adornato, Antonella Del Corso, Massimo Genovese, Ilaria Nesi, Roberta Moschini, Alexandra Naß, GerhardWolber and Rosanna Maccari, | |
| Studying the trafficking of labeled trodusquemine and its application as nerve marker for light-sheet and expansion microscopy | 2022 | Claudia Capitini, Luca Pesce, Giulia Fani, Giacomo Mazzamuto, Massimo Genovese, Alessandra Franceschini, Paolo Paoli, Giuseppe Pieraccini, Michael Zasloff, Fabrizio Chiti, Francesco S Pavone, Martino Calamai |