Distribuzione geografica
Continente #
NA - Nord America 5.539
EU - Europa 2.416
AS - Asia 368
AF - Africa 18
OC - Oceania 3
SA - Sud America 3
Totale 8.347
Nazione #
US - Stati Uniti d'America 5.518
SE - Svezia 451
IE - Irlanda 429
PL - Polonia 386
UA - Ucraina 318
IT - Italia 290
DE - Germania 221
HK - Hong Kong 166
FI - Finlandia 117
JO - Giordania 105
GB - Regno Unito 92
CH - Svizzera 42
TR - Turchia 39
FR - Francia 26
IN - India 26
BE - Belgio 23
CN - Cina 22
CA - Canada 21
SC - Seychelles 16
NL - Olanda 11
VN - Vietnam 7
RU - Federazione Russa 4
AR - Argentina 2
ES - Italia 2
IR - Iran 2
LT - Lituania 2
MU - Mauritius 2
NZ - Nuova Zelanda 2
AT - Austria 1
AU - Australia 1
AZ - Azerbaigian 1
BY - Bielorussia 1
CO - Colombia 1
Totale 8.347
Città #
Fairfield 896
Jacksonville 529
Chandler 522
Dublin 429
Woodbridge 416
Ashburn 386
Warsaw 384
Cambridge 370
Seattle 365
Houston 320
Wilmington 294
Ann Arbor 194
Altamura 124
Princeton 116
Boardman 115
Lawrence 103
Medford 82
Hong Kong 67
Boston 54
San Diego 44
Bern 42
Izmir 37
Kent 26
Norwalk 25
Brussels 23
Florence 22
Auburn Hills 21
Milan 20
Buffalo 17
Falls Church 16
Los Angeles 16
Toronto 14
Beijing 13
Frankfurt Am Main 13
West Jordan 12
Andover 10
Hillsboro 10
Salerno 10
London 9
Verona 9
New York 8
Shanghai 8
Halle 6
Düsseldorf 5
Incisa 5
Bremen 4
Dong Ket 4
Laurel 4
Redwood City 4
Saint-Fons 4
Trumbull 4
Winnipeg 4
Chicago 3
Napoli 3
Phoenix 3
Serra 3
Dallas 2
Helsinki 2
Leipzig 2
Lugo 2
Montréal 2
Naaldwijk 2
Naples 2
San Mateo 2
Scandicci 2
Vilnius 2
Auckland 1
Baku 1
Burleson 1
Central 1
Chiswick 1
Giugliano In Campania 1
Grenoble 1
Grevenbroich 1
Groningen 1
Hamilton 1
Hanoi 1
Islington 1
Lappeenranta 1
Minsk 1
Modena 1
Mumbai 1
Old Bridge 1
Ottawa 1
Perth 1
Poggio A Caiano 1
Redmond 1
Saint Petersburg 1
San Luis 1
Seegebiet Mansfelder Land 1
Torino 1
Uppsala 1
Vienna 1
Wandsworth 1
Washington 1
Wuhan 1
Totale 6.297
Nome #
Biotransformation of Chloroaromatics: the Impact of Bioavailability and Substrate Specificity. 250
Structure and function of Aspergillus niger laccase McoG 221
Crystal structure of a blue laccase from Lentinus tigrinus: evidences for intermediates in the molecular oxygen reductive splitting by multicopper oxidases. 195
Carbonic anhydrase activators: X-ray crystallographic and spectroscopic investigations for the interaction of isozymes I and II with histamine. 115
Characterization of the biological conversion of naphthalene to (+)-cis-(1R,2S)-dihydroxy-1,2-dihydronaphthalene in direct micellar systems 112
Combined action of a bacterial monooxygenase and a fungal laccase for the biodegradation of mono- and poly-aromatic hydrocarbons. 109
Efficient polycyclic aromatic hydrocarbons dihydroxylation in direct micellar systems 106
Carbonic Anhydrase Inhibitors. Part 55 Metal Complexes of 1,3,4-Thiadiazole-2-Sulfonamide Derivatives: In Vitro Inhibition Studies With Carbonic Anhydrase Isozymes I, II and IV. 103
Complexes with biologically active ligands. Part 11. Synthesis and carbonic anhydrase inhibitory activity of metal complexes of 4,5-disubstituted-3-mercapto-1,2,4-triazole derivatives. 103
Crystallization and preliminary structure analysis of the blue laccase from the ligninolytic fungus Panus tigrinus. 103
Carbonic Anhydrase Interaction With Lipothioars Enites: A Novel Class of Isozymes I and II Inhibitors. 103
X-ray structures of 4-chlorocatechol 1,2-dioxygenase adducts with substituted catechols: New perspectives in the molecular basis of intradiol ring cleaving dioxygenases specificity. 103
Salicylate 1,2-dioxygenase from Pseudaminobacter salicylatoxidans: crystal structure of a peculiar ring-cleaving dioxygenase. 101
Complexes with biologically active ligands. Part 9 metal complexes of 5-benzoylamino- and 5-(3-nitrobenzoyl-amino)-1,3,4-thiadiazole-2-sulfonamide as carbonic anhydrase inhibitors. 100
Crystal structure of the blue multicopper oxidase from the white-rot fungus Trametes trogii complexed with p-toluate 97
Carbonic Anhydrase Activators. Part 19 Spectroscopic and Kinetic Investigations for the Interaction of Isozymes I and II With Primary Amines. 96
The generation of a 1-hydroxy-2-naphthoate 1,2-dioxygenase by single point mutations of salicylate 1,2-dioxygenase – Rational design of mutants and the crystal structures of the A85H and W104Y variants 96
Role of surfactants in optimizing fluorene assimilation and intermediate formation by Rhodococcus rhodochrous VKM B-2469. 96
Crystal structure of 3-chlorocatechol 1,2-dioxygenase key enzyme of a new modified ortho-pathway from the Gram-positive Rhodococcus opacus 1CP grown on 2-chlorophenol. 94
Structural roles of the active site iron(III) ions in catechol 1,2-dioxygenases and differential secondary structure changes in isoenzymes A and B from Acinetobacter radioresistens S13. 94
H-1 Noe Studies Of Oxidized High-Potential Iron Sulfur Protein-II From Ectothiorhodospira-Halophila 93
Nonionic micelles promote whole cell bioconversion of aromatic substrates in an aqueous environment. 91
Carbonic anhydrase inhibitors. metal complexes of 5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide with topical intraocular pressure lowering properties: the influence of metal ions upon the pharmacological activity. 90
H-1-Nmr Studies On Partially And Fully Reduced 2(4fe-4s) Ferredoxin From Clostridium-Pasteurianum 90
Evaluation of an FIA operated amperometric bacterial biosensor, based on pseudomonas putida F1 for the detection of benzene, toluene, ethylbenzene, and xylenes (BTEX) 90
Biodegradation of naphthalenesulphonate polymers: the potential of a combined application of fungi and bacteria 88
Direct Micellar Systems as a Tool to Improve the Efficiency of Aromatic Substrate Conversion for Fine Chemicals Production 87
Natural Tannins For Leather Treatments: Biodegradation By Penicillium Chrysogenum Mut 4444 On A Fixed Bed Bioreactor 87
Carbonic anhydrase catalyzes cyanamide hydration to urea: is it mimicking the physiological reaction? 86
The salicylate 1,2-dioxygenase as a model for a conventional gentisate 1,2-dioxygenase: crystal structures of the G106A mutant and its adducts with gentisate and salicylate. 86
Crystallization and preliminary crystallographic analysis of the hydroxyquinol 1,2-dioxygenase from Nocardioides simplex 3E: a novel dioxygenase involved in the biodegradation of polychlorinated aromatic compounds. 86
Carbonic anhydrase inhibitors. Water-soluble, topically effective intraocular pressure lowering agents derived from isonicotinic acid and aromatic/heterocyclic sulfonamides: is the tail more important than the ring? 85
Reaction Intermediates and Redox State Changes in a Blue Laccase from Steccherinum ochraceum observed by Crystallographic High/Low X-Ray Dose Experiments 85
Fungal laccase, cellobiose dehydrogenase, and chemical mediators: combined actions for the decolorization of different classes of textile dyes. 84
Carbonic Anhydrase Inhibitors Part 72 Synthesis and Antiglaucoma Properties of Metal Complexes of p-Fluorobenzolamide. 84
Differential decolorization of textile dyes in mixtures and the joint effect of laccase and cellobiose dehydrogenase activities present in extracellular extracts from Funalia trogii. 84
Crystal analysis of aromatic sulfonamide binding to native and (Zn)2 adduct of human carbonic anhydrase I Michigan 1. 82
Catechol 1,2-dioxygenase from the Gram-positive Rhodococcus opacus 1CP: Quantitative structure/activity relationship and the crystal structures of native enzyme and catechols adducts 82
Carbonic anhydrase inhibitors: sulfonamides as antitumor agents? 81
Carbonic anhydrase inhibitors. Schiff bases of some aromatic sulfonamides and their metal complexes: towards more selective inhibitors of carbonic anhydrase isozyme IV. 80
In vitro dissociation and reassociation of human alcohol dehydrogenase class I isozymes. 80
Sulfenamido-sulfonamides as inhibitors of carbonic anhydrase isozymes I, II and IV. 80
Protease inhibitors - Part 3. Synthesis of non-basic thrombin inhibitors incorporating pyridinium-sulfanilylguanidine moieties at the P1 site. 79
Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating 2,4,6-trisubstituted-pyridinium-ethylcarboxamido moieties possessing membrane-impermeability and in vivo selectivity for the membrane-bound (CA IV) versus the cytosolic (CA I and CA II) isozymes. 79
Quantitative structure/activity relationship for the rate of conversion of C4-substituted catechols by catechol-1,2-dioxygenase from Pseudomonas putida (arvilla) C1. 79
Crystal Structure Determination of a Salicylate 1,2-Dioxygenase from Pseudaminobacter salicylatoxidans 78
H-1-Nmr Studies Of Chromatium-Vinosum Cytochrome-C' 78
Carbonic anhydrase inhibitors: perfluoroalkyl/aryl-substituted derivatives of aromatic/heterocyclic sulfonamides as topical intraocular pressure-lowering agents with prolonged duration of action. 77
Carbonic anhydrase inhibitors: synthesis of water-soluble, aminoacyl/dipeptidyl sulfonamides possessing long-lasting intraocular pressure-lowering properties via the topical route. 76
Crystal structure of 4-chlorocatechol 1,2-dioxygenase from the chlorophenol-utilizing gram-positive Rhodococcus opacus 1CP 75
Characterization of an intradiol dioxygenase involved in the biodegradation of the chlorophenoxy herbicides 2,4-D and 2,4,5-T. 75
Hydroxyquinol 1,2-dioxygenase 75
Biophysical investigation of bacterial aromatic extradiol dioxygenases involved in biodegradation processes 74
Crystal analysis of Aromatic sulfonamide binding to native and (Zn)2adduct to Human Carbonic Anhydrase I Michigan 1 74
Carbonic anhydrase inhibitors: synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus cytosolic isozymes. 74
The Tetranuclear Trianion [Fe4te4(Sc6h5)4]3- - Crystal And Molecular-Structure And Magnetic-Properties 74
Protease inhibitors: Part 4. Synthesis of weakly basic thrombin inhibitors incorporating pyridinium-sulfanilylaminoguanidine moieties. 74
Preliminary Crystallographic Analysis of 3-Chlorocatechol 1,2-Dioxygenase of a New Modified Ortho-pathway from the Gram-Positive Rhodococcus opacus 1CP Grown on 2-Chlorophenol. 73
Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring? 72
Enzymatic decolorization of spent textile dyeing baths composed by mixtures of synthetic dyes and additives. 72
Nuclear Magnetic-Relaxation Dispersion Studies Of Hexaaquo Mn(Ii) Ions In Water Glycerol Mixtures 72
H-1-Nmr Studies On Reduced High-Potential Iron Protein (Hipip) From Chromatium-Vinosum 71
Double Exchange Versus J Inequality In Fe3s40 Clusters 71
Carbonic anhydrase inhibitors: N-cyanosulfonamides, a new class of high affinity isozyme II and IV inhibitors. 71
Crystal structure of a zinc-activated variant of Human Carbonic Anhydrase I, CA I Michigan 1: evidence for a second zinc binding site involving arginine coordination 70
Purification, biochemical properties and substrate specificity of a catechol 1,2-dioxygenase from a phenol degrading Acinetobacter radioresistens. 70
Mechanism of cyanamide hydration catalyzed by carbonic anhydrase II suggested by cryogenic X-ray diffraction. 69
Protease inhibitors: synthesis and QSAR study of novel classes of nonbasic thrombin inhibitors incorporating sulfonylguanidine and O-methylsulfonylisourea moieties at P1. 69
Function of different amino acid residues in the reaction mechanism of gentisate 1,2-dioxygenases deduced from the analysis of mutants of the salicylate 1,2-dioxygenase from Pseudaminobacter salicylatoxidans 69
Chlorocatechol 1, 2-dioxygenase from the Chlorophenol-utilizing Gram-positive Rhodococcus opacus 1CP: Crystallization and preliminary crystallographic analysis 69
Effects of surface hydrophobicity on the catalytic iron ion retention in the active site of two catechol 1,2-dioxygenase isoenzymes. 68
X-Ray-Absorption Studies On Catechol 2,3-Dioxygenase From Pseudomonas-Putida Mt2 67
Crystal structures of salicylate 1,2-dioxygenase-substrates adducts: A step towards the comprehension of the structural basis for substrate selection in class III ring cleaving dioxygenases 65
Preliminary crystallographic analysis of salicylate 1,2-dioxygenase from Pseudaminobacter salicylatoxidans. 64
Proton Nmr-Spectroscopy Of Flavocytochrome-C552 From Chromatium-Vinosum 64
Aliphatic And Aromatic Inhibitors Binding To The Active-Site Of Catechol 2,3-Dioxygenase From Pseudomonas-Putida Mt-2 62
Laccase isoforms with unusual properties from the basidiomycete Steccherinum ochraceum strain 1833 62
Novel carbonic anhydrase isozymes I, II and IV activators incorporating sulfonyl-histamino moieties. 60
2d H-1-Nmr Studies Of Oxidized 2(Fe4s4) Ferredoxin From Clostridium-Pasteurianum 60
Carbonic anhydrase inhibitors. Part 60(#). The topical intraocular pressure-lowering properties of metal complexes of a heterocyclic sulfonamide: influence of the metal ion upon biological activity. 59
Protease inhibitors. Part 2. Weakly basic thrombin inhibitors incorporating sulfonyl-aminoguanidine moieties as S1 anchoring groups: synthesis and structure-activity correlations. 57
Carbonic anhydrase inhibitors. Part 79. Synthesis of topically acting sulfonamides incorporating GABA moieties in their molecule, with long-lasting intraocular pressure-lowering properties. 57
Carbonic anhydrase inhibitors .37. Novel classes of isozyme I and II inhibitors and their mechanism of action. Kinetic and spectroscopic investigations on native and cobalt-substituted enzymes 56
H-1-Nmr Spectra Of Oxidized High-Potential Iron Sulfur Protein (Hipip) From Rhodocyclus-Gelatinosus - A Model For Oxidized Hipips 54
Carbonic anhydrase inhibitors - part 78(#). Synthesis of water-soluble sulfonamides incorporating beta-alanyl moieties, possessing long lasting-intraocular pressure lowering properties via the topical route. 52
Biochemical properties and substrate specificity of a catechol 1,2-dioxygenase from a phenol degrading acinetobacter radioresistens 51
4-Chlorocatechol 1,2-dioxygenase fromthe chlorophenol-utilizing Gram-positive Rhodococcus opacus1CP: crystallization and preliminary crystallographic analysis. 51
The electron-nucleus dipolar coupling in slow rotating systems. 2. The effect of g anisotropy and hyperfine coupling when S=1/2 and I=3/2 49
Carbonic anhydrase inhibitors. Part 71. Synthesis and ocular pharmacology of a new class of water-soluble, topically effective intraocular pressure lowering sulfonamides incorporating picolinoyl moieties. 49
Crystal structure of the hydroxyquinol 1,2-dioxygenase from Nocardioides simplex 3E, a key enzyme involved in polychlorinated aromatics biodegradation 49
Carbonic anhydrase inhibitors: synthesis of water-soluble, topically effective intraocular pressure lowering aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl moieties: is the tail more important than the ring? 48
Carbonic anhydrase inhibitors. Part 37#. Novel classes of isozymes I and II inhibitors and their mechanism of action. Kinetic and spectroscopic investigations on the native and cobalt-substituted enzymes 47
Efficient Polyciclic aromatic hydrocarbons dihydroxylation in direct micellar systems 45
Carbonic anhydrase inhibitors: inhibition of isozymes I, II and IV with N-hydroxysulfonamides--a novel class of intraocular pressure lowering agents. 44
Protease inhibitors: Synthesis of L-alanine hydroxamate sulfonylated derivatives as inhibitors of clostridium histolyticum collagenase. 42
The Electronic-Structure Of Paramagnetic Polynuclear Metal-Clusters In Proteins Studied Through H-1-Nmr Spectroscopy 41
Magnetic relaxation of solvent protons by Cu2+ - and VO2+ - substituted transferrin: theoretical analysis and biochemical implacations 41
The electron-nucleus dipolar coupling in slow rotating systems. 4. The effect of zero-field splitting and hyperfine coupling when S= 5/2 and I= 5/2. 41
Sulfonylamido derivatives of 2-aminophenoxathiin-10,10-dioxide and related compounds possess antifungal action due to the possible inhibition of lanosterol-14-alpha-demethylase. 41
XAS characterization of the active sites of novel intradiol ring cleaving dioxygenases:hydroxyquinol and chlocatechol dioxygenases 41
Totale 7.924
Categoria #
all - tutte 21.169
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 21.169

Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019762 0 0 0 0 0 0 0 0 0 0 413 349
2019/20202.065 180 171 32 219 207 289 207 289 194 87 159 31
2020/20211.237 100 63 141 118 37 170 16 136 84 158 79 135
2021/2022710 30 47 28 51 62 49 25 37 48 30 128 175
2022/20232.055 224 331 38 181 200 348 237 108 274 8 50 56
2023/2024450 22 86 118 40 17 44 5 75 1 15 27 0
Totale 8.367