CHIARAMONTE, NICCOLO'
CHIARAMONTE, NICCOLO'
Neuroscienze, Psicologia, Area del Farmaco e Salute del Bambino (NEUROFARBA)
2-(2-Hydroxyethyl)piperazine derivatives as potent human carbonic anhydrase inhibitors: Synthesis, enzyme inhibition, computational studies and antiglaucoma activity
2022 Chiaramonte N.; Angeli A.; Sgambellone S.; Bonardi A.; Nocentini A.; Bartolucci G.; Braconi L.; Dei S.; Lucarini L.; Teodori E.; Gratteri P.; Wunsch B.; Supuran C.T.; Romanelli M.N.
2-Benzylpiperazine: a new scaffold for potent human Carbonic Anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents.
2018 Niccolò Chiaramonte, Silvia Bua, Marta Ferraroni, Alessio Nocentini, Alessandro Bonardi, Gian Luca Bartolucci, Maria Concetta Durante, Laura Lucarini, Donata Chiapponi, Silvia Dei, Dina Manetti, Elisabetta Teodori, Paola Gratteri, Emanuela Masini, Claudiu T. Supuran, Maria Novella Romanelli
6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline amides and corresponding ester isosteres as multidrug resistance reversers
2020 Braconi L.; Bartolucci G.; Contino M.; Chiaramonte N.; Giampietro R.; Manetti D.; Perrone M.G.; Romanelli M.N.; Colabufo N.A.; Riganti C.; Dei S.; Teodori E.
Amino acids as building blocks for carbonic anhydrase inhibitors
2018 Chiaramonte, Niccolò*; Romanelli, Maria Novella; Teodori, Elisabetta; Supuran, Claudiu T.
Carbonic Anhydrase IV Selective Inhibitors Counteract the Development of Colitis-Associated Visceral Pain in Rats
2021 Lucarini E., Nocentini A., Bonardi A., Chiaramonte N., Parisio C., Micheli L., Toti A., Ferrara V., Carrino D., Pacini A., Romanelli M.N., Supuran C.T., Ghelardini C., Di Cesare Mannelli L.
Design and synthesis of aminoester heterodimers containing flavone or chromone moieties as modulators of P-glycoprotein-based multidrug resistance (MDR)
2018 Silvia, Dei; Maria Novella Romanelli, ; Dina, Manetti; Niccolò, Chiaramonte; Marcella, Coronnello; Milena, Salerno; Elisabetta, Teodori
Design, synthesis and preliminary biological evaluation of modulators of metalloenzymes
2020 Niccolò Chiaramonte
Designing selective modulators for the nicotinic receptor subtypes: challenges and opportunities
2018 Dina Manetti, Cristina Bellucci, Niccolo` Chiaramonte, Silvia Dei, Elisabetta Teodori, Maria Novella Romanelli
Dual HDAC–BRD4 inhibitors endowed with antitumor and antihyperalgesic activity
2022 Maach S.; Chiaramonte N.; Borgonetti V.; Sarno F.; Pierucci F.; Dei S.; Teodori E.; Altucci L.; Meacci E.; Galeotti N.; Romanelli M.N.
Investigation of piperazines as human carbonic anhydrase I, II, IV and VII activators
2018 Angeli, Andrea; Chiaramonte, Niccolò; Manetti, Dina; Romanelli, Maria Novella; Supuran, Claudiu T
Modulation of the spacer in N,N-bis(alkanol)amine aryl ester heterodimers led to the discovery of a series of highly potent P-glycoprotein-based multidrug-resistance (MDR) modulators
2019 Silvia Dei, Laura Braconi, Alfonso Trezza, Marta Menicatti, Marialessandra Contino, Marcella Coronnello, Niccolò Chiaramonte, Dina Manetti, Maria Grazia Perrone, Maria Novella Romanelli, Chatchanok Udomtanakunchai, Nicola Antonio Colabufo, Gian luca Bartolucci, Ottavia Spiga, Milena Salerno, Elisabetta Teodori
New Histamine-Related Five-Membered N-Heterocycle Derivatives as Carbonic Anhydrase I Activators
2022 Chiaramonte N.; Gabellini A.; Angeli A.; Bartolucci G.; Braconi L.; Dei S.; Teodori E.; Supuran C.T.; Romanelli M.N.
New Rigid Nicotine Analogues, Carrying a Norbornane Moiety, Are Potent Agonists of α7 and α3∗ Nicotinic Receptors
2019 Dina Manetti*† , Alexandra Garifulina‡, Gian Luca Bartolucci , Carla Bazzicalupi§ , Cristina Bellucci†, Niccolò Chiaramonte†, Silvia Dei†, Lorenzo Di Cesare Mannelli∥, Carla Ghelardini∥, Paola Gratteri⊥ , Ekaterina Spirova‡, Irina Shelukhina‡, Elisabetta Teodori†, Katia Varani#, Victor Tsetlin‡, Maria Novella Romanelli†
Synthesis and carbonic anhydrase activating properties of a series of 2-amino-imidazolines structurally related to clonidine
2020 Niccolò Chiaramonte, Soumia Maach, Caterina Biliotti, Andrea Angeli, Gian luca Bartolucci, Laura Braconi, Silvia Dei, Elisabetta Teodori, Claudiu T. Supuran, Maria Novella Romanelli
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 2-(2-Hydroxyethyl)piperazine derivatives as potent human carbonic anhydrase inhibitors: Synthesis, enzyme inhibition, computational studies and antiglaucoma activity | 2022 | Chiaramonte N.; Angeli A.; Sgambellone S.; Bonardi A.; Nocentini A.; Bartolucci G.; Braconi L.; Dei S.; Lucarini L.; Teodori E.; Gratteri P.; Wunsch B.; Supuran C.T.; Romanelli M.N. | |
| 2-Benzylpiperazine: a new scaffold for potent human Carbonic Anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents. | 2018 | Niccolò Chiaramonte, Silvia Bua, Marta Ferraroni, Alessio Nocentini, Alessandro Bonardi, Gian Luca Bartolucci, Maria Concetta Durante, Laura Lucarini, Donata Chiapponi, Silvia Dei, Dina Manetti, Elisabetta Teodori, Paola Gratteri, Emanuela Masini, Claudiu T. Supuran, Maria Novella Romanelli | |
| 6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline amides and corresponding ester isosteres as multidrug resistance reversers | 2020 | Braconi L.; Bartolucci G.; Contino M.; Chiaramonte N.; Giampietro R.; Manetti D.; Perrone M.G.; Romanelli M.N.; Colabufo N.A.; Riganti C.; Dei S.; Teodori E. | |
| Amino acids as building blocks for carbonic anhydrase inhibitors | 2018 | Chiaramonte, Niccolò*; Romanelli, Maria Novella; Teodori, Elisabetta; Supuran, Claudiu T. | |
| Carbonic Anhydrase IV Selective Inhibitors Counteract the Development of Colitis-Associated Visceral Pain in Rats | 2021 | Lucarini E., Nocentini A., Bonardi A., Chiaramonte N., Parisio C., Micheli L., Toti A., Ferrara V., Carrino D., Pacini A., Romanelli M.N., Supuran C.T., Ghelardini C., Di Cesare Mannelli L. | |
| Design and synthesis of aminoester heterodimers containing flavone or chromone moieties as modulators of P-glycoprotein-based multidrug resistance (MDR) | 2018 | Silvia, Dei; Maria Novella Romanelli, ; Dina, Manetti; Niccolò, Chiaramonte; Marcella, Coronnello; Milena, Salerno; Elisabetta, Teodori | |
| Design, synthesis and preliminary biological evaluation of modulators of metalloenzymes | 2020 | Niccolò Chiaramonte | |
| Designing selective modulators for the nicotinic receptor subtypes: challenges and opportunities | 2018 | Dina Manetti, Cristina Bellucci, Niccolo` Chiaramonte, Silvia Dei, Elisabetta Teodori, Maria Novella Romanelli | |
| Dual HDAC–BRD4 inhibitors endowed with antitumor and antihyperalgesic activity | 2022 | Maach S.; Chiaramonte N.; Borgonetti V.; Sarno F.; Pierucci F.; Dei S.; Teodori E.; Altucci L.; Meacci E.; Galeotti N.; Romanelli M.N. | |
| Investigation of piperazines as human carbonic anhydrase I, II, IV and VII activators | 2018 | Angeli, Andrea; Chiaramonte, Niccolò; Manetti, Dina; Romanelli, Maria Novella; Supuran, Claudiu T | |
| Modulation of the spacer in N,N-bis(alkanol)amine aryl ester heterodimers led to the discovery of a series of highly potent P-glycoprotein-based multidrug-resistance (MDR) modulators | 2019 | Silvia Dei, Laura Braconi, Alfonso Trezza, Marta Menicatti, Marialessandra Contino, Marcella Coronnello, Niccolò Chiaramonte, Dina Manetti, Maria Grazia Perrone, Maria Novella Romanelli, Chatchanok Udomtanakunchai, Nicola Antonio Colabufo, Gian luca Bartolucci, Ottavia Spiga, Milena Salerno, Elisabetta Teodori | |
| New Histamine-Related Five-Membered N-Heterocycle Derivatives as Carbonic Anhydrase I Activators | 2022 | Chiaramonte N.; Gabellini A.; Angeli A.; Bartolucci G.; Braconi L.; Dei S.; Teodori E.; Supuran C.T.; Romanelli M.N. | |
| New Rigid Nicotine Analogues, Carrying a Norbornane Moiety, Are Potent Agonists of α7 and α3∗ Nicotinic Receptors | 2019 | Dina Manetti*† , Alexandra Garifulina‡, Gian Luca Bartolucci , Carla Bazzicalupi§ , Cristina Bellucci†, Niccolò Chiaramonte†, Silvia Dei†, Lorenzo Di Cesare Mannelli∥, Carla Ghelardini∥, Paola Gratteri⊥ , Ekaterina Spirova‡, Irina Shelukhina‡, Elisabetta Teodori†, Katia Varani#, Victor Tsetlin‡, Maria Novella Romanelli† | |
| Synthesis and carbonic anhydrase activating properties of a series of 2-amino-imidazolines structurally related to clonidine | 2020 | Niccolò Chiaramonte, Soumia Maach, Caterina Biliotti, Andrea Angeli, Gian luca Bartolucci, Laura Braconi, Silvia Dei, Elisabetta Teodori, Claudiu T. Supuran, Maria Novella Romanelli |