BIGI, ALESSANDRA

BIGI, ALESSANDRA  

Scienze Biomediche, Sperimentali e Cliniche 'Mario Serio'  

Mostra records
Risultati 1 - 20 di 23 (tempo di esecuzione: 0.03 secondi).
Titolo Data di pubblicazione Autore(i) File
A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43 2022 Roberta Cascella, Alessandra Bigi, Dylan Giorgino Riffert, Maria Cristina Gagliani, Emilio Ermini, Matteo Moretti, Katia Cortese, Cristina Cecchi, Fabrizio Chiti
Amyloid fibrils act as a reservoir of soluble oligomers, the main culprits in protein deposition diseases 2022 Alessandra Bigi, Roberta Cascella, Fabrizio Chiti, Cristina Cecchi
An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature 2023 Cascella R, Banchelli M, Abolghasem Ghadami S, Ami D, Gagliani MC, Bigi A, Staderini T, Tampellini D, Cortese K, Cecchi C, Natalello A, Adibi H, Matteini P, Chiti F.
An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature 2023 Roberta Cascella, Martina Banchelli, Seyyed Abolghasem Ghadami, Diletta Ami, Maria Cristina Gagliani, Alessandra Bigi, Tommaso Staderini, Davide Tampellini, Katia Cortese, Cristina Cecchi, Antonino Natalello, Hadi Adibi, Paolo Matteini, Fabrizio Chiti
APP and Bace1: Differential effect of cholesterol enrichment on processing and plasma membrane mobility 2023 Claudia Capitini, Alessandra Bigi, Niccolò Parenti, Marco Emanuele, Niccolò Bianchi, Roberta Cascella, Cristina Cecchi, Laura Maggi, Francesco Annunziato, Francesco Saverio Pavone, Martino Calamai
Biophysical characterization of full length TAR DNA-Binding Protein (TDP-43) phase separation 2022 Tommaso Staderini, Alessandra Bigi, Daniele Mongiello, Cristina Cecchi, Fabrizio Chiti
Biophysical characterization of full-length TAR DNA-binding protein (TDP-43) phase separation. 2022 Tommaso Staderini, Alessandra Bigi, Daniele Mongiello, Cristina Cecchi, Fabrizio Chiti
Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies 2022 Roberta Cascella, Alessandra Bigi, Nunilo Cremades, Cristina Cecchi
Exploring the release of toxic oligomers from α-synuclein fibrils with antibodies and sted microscopy 2021 Bigi A.; Ermini E.; Chen S.W.; Cascella R.; Cecchi C.
Identification of Novel 1,3,5-Triphenylbenzene Derivative Compounds as Inhibitors of Hen Lysozyme Amyloid Fibril Formation 2019 Hassan Ramshini , Reza Tayebee, Alessandra Bigi, Francesco Bemporad, Cristina Cecchi, Fabrizio Chiti
Partial Failure of Proteostasis Systems Counteracting TDP-43 Aggregates in Neurodegenerative Diseases 2019 Cascella R, Fani G, Bigi A, Chiti F, Cecchi C.
Secreted sphingosine 1-phosphate exerts a novel autocrine action in bone marrow-derived mesenchymal stromal cell signalling 2016 Pierucci, F; Sassoli, C; Tani, A; Frati, A; Bigi, A; Chellini, F; Matteini, F; Anderloni, G; Nosi, D; Mazzanti, B; Zecchi-Orlandini, S; Meacci, E
Soluble Oligomers Require a Ganglioside to Trigger Neuronal Calcium Overload 2017 Cascella, Roberta; Evangelisti, Elisa; Bigi, Alessandra; Becatti, Matteo; Fiorillo, Claudia; Stefani, Massimo; Chiti, Fabrizio; Cecchi, Cristina
Sphingosine 1-phosphate attenuates neuronal dysfunction induced by amyloid-β oligomers through endocytic internalization of NMDA receptors 2023 Bigi A, Cascella R, Fani G, Bernacchioni C, Cencetti F, Bruni P, Chiti F, Donati C, Cecchi C.
Squalamine and its derivatives modulate the aggregation of amyloid-β and α-synuclein and suppress the toxicity of their oligomers 2021 Ryan Limbocker, Roxine Staats, Sean Chia, Francesco S Ruggeri, Benedetta Mannini, Catherine K Xu, Michele Perni, Roberta Cascella, Alessandra Bigi, Liam R Sasser, Natalie R Block, Aidan K Wright, Ryan P Kreiser, Edward T Custy, Georg Meisl, Silvia Errico, Johnny Habchi, Patrick Flagmeier, Tadas Kartanas, Jared E Hollows, Lam T Nguyen, Kathleen LeForte, Denise Barbut, Janet R Kumita, Cristina Cecchi, Michael Zasloff, Tuomas P J Knowles, Christopher M Dobson, Fabrizio Chiti, Michele Vendruscolo
Study of the relationship between structure and toxicity of different α-synuclein aggregates and related cellular dysfunctions 2020 Alessandra Bigi
Targeting pathological amyloid aggregates with conformation-sensitive antibodies 2020 Alessandra Bigi, Gilda Loffredo, Roberta Cascella, Cristina Cecchi
The acute myeloid leukemia-associated nucleophosmin 1 gene mutations dictate amyloidogenicity of the C-terminal domain 2019 La Manna, Sara; Scognamiglio, Pasqualina; Roviello, Valentina; Borbone, Fabio; Florio, Daniele; Di Natale, Concetta ; Bigi, Alessandra; Cecchi, Cristina; Cascella, Roberta; Giannini, Cinzia; Sibillano, Teresa; Novellino, Ettore; Marasco, Daniela
The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells 2021 Roberta Cascella, Serene W Chen , Alessandra Bigi, José D Camino, Catherine K Xu, Christopher M Dobson, Fabrizio Chiti, Nunilo Cremades, Cristina Cecchi
The Toxicity of Protein Aggregates: New Insights into the Mechanisms 2023 Alessandra Bigi, Eva Lombardo, Roberta Cascella, Cristina Cecchi