New low-cost strategies and enhancement of the already described methods to manu- facture peptide molecules on an industrial scale are highly requested, particularly for peptides such as octreotide, which, along with goserelin and leuprolide, dominate the global peptide market. A number of patents related to the production of octreotide can be found, concerning both solution and solid- phase synthesis. Thus, there is a need to revise the existing synthetic approaches in order to organize them in a more comprehensible way.
Production of peptides as generic drugs: A patent landscape of octreotide / Sabatino, G., Guryanov, I., Rombecchi, A., Zanon, J., Ricci, A., Cabri, W., Papini, A.M., Rovero, P.. - In: EXPERT OPINION ON THERAPEUTIC PATENTS. - ISSN 1354-3776. - ELETTRONICO. - 26:(2016), pp. 485-495. [10.1517/13543776.2016.1158810]
Production of peptides as generic drugs: A patent landscape of octreotide
SABATINO, GIUSEPPINA;PAPINI, ANNA MARIA;ROVERO, PAOLO
2016
Abstract
New low-cost strategies and enhancement of the already described methods to manu- facture peptide molecules on an industrial scale are highly requested, particularly for peptides such as octreotide, which, along with goserelin and leuprolide, dominate the global peptide market. A number of patents related to the production of octreotide can be found, concerning both solution and solid- phase synthesis. Thus, there is a need to revise the existing synthetic approaches in order to organize them in a more comprehensible way.
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