Modular approach for bimodal antibacterial surfaces combining photo-switchable activity and sustained biocidal release

Pallavicini, Piersandro; Bassi, Barbara; Chirico, Giuseppe; Collini, Maddalena; Dacarro, Giacomo; Fratini, Emiliano; Grisoli, Pietro; Patrini, Maddalena; Sironi, Laura; Taglietti, Angelo; Moritz, Marcel; Sorzabal-Bellido, Ioritz; Susarrey-Arce, Arturo; Latter, Edward; Beckett, Alison J.; Prior, Ian A.; Raval, Rasmita; Diaz Fernandez, Yuri A.

doi:10.1038/s41598-017-05693-3

Photo-responsive antibacterial surfaces combining both on-demand photo-switchable activity and sustained biocidal release were prepared using sequential chemical grafting of nano-objects with different geometries and functions. The multi-layered coating developed incorporates a monolayer of near-infrared active silica-coated gold nanostars (GNS) decorated by silver nanoparticles (AgNP). This modular approach also enables us to unravel static and photo-activated contributions to the overall antibacterial performance of the surfaces, demonstrating a remarkable synergy between these two mechanisms. Complementary microbiological and imaging evaluations on both planktonic and surface-attached bacteria provided new insights on these distinct but cooperative effects.

Modular approach for bimodal antibacterial surfaces combining photo-switchable activity and sustained biocidal release / Pallavicini, P., Bassi, B., Chirico, G., Collini, M., Dacarro, G., Fratini, E., Grisoli, P., Patrini, M., Sironi, L., Taglietti, A., Moritz, M., Sorzabal-Bellido, I., Susarrey-Arce, A., Latter, E., Beckett, A.J., Prior, I.A., Raval, R., Diaz Fernandez, Y.A.. - In: SCIENTIFIC REPORTS. - ISSN 2045-2322. - STAMPA. - 7:(2017), pp. 0-0. [10.1038/s41598-017-05693-3]