The present invention refers to novel thiazolo[5,4-d]pyrimidine derivs. that are inverse agonists of the adenosine A2A receptor, to a process for their prepn., to the pharmaceutical compns. contg. them and to their use in the medical field, in particular in the therapeutic treatment of diseases or disorders assocd. to an activity of the adenosine A2A receptor, and more in particular in the therapeutic treatment of neurol. diseases, of pain, of cancer, and of dermal fibrosis and scarring.
Novel Thiazolo[4,5-d]pyrimidine derivatives as inverse agonists of A2A adenosine receptors / Flavia, Varano; Vittoria, Colotta; Daniela, Catarzi; Katia, Varani; Pier Andrea Borea, ; Fabrizio, Vincenzi. - (2018).
Novel Thiazolo[4,5-d]pyrimidine derivatives as inverse agonists of A2A adenosine receptors
Flavia Varano;Vittoria Colotta;Daniela Catarzi;
2018
Abstract
The present invention refers to novel thiazolo[5,4-d]pyrimidine derivs. that are inverse agonists of the adenosine A2A receptor, to a process for their prepn., to the pharmaceutical compns. contg. them and to their use in the medical field, in particular in the therapeutic treatment of diseases or disorders assocd. to an activity of the adenosine A2A receptor, and more in particular in the therapeutic treatment of neurol. diseases, of pain, of cancer, and of dermal fibrosis and scarring.
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