OCTA Imaging of Choroidal Neovascularization Treated Using Photodynamic Therapy in a Young Patient With Best Macular Dystrophy

This study reports the onset of a choroidal neovascularization (CNV) in a young patient affected with Best macular dystrophy (BMD) using optical coherence tomography angiography (OCTA) and describes its changes after photodynamic therapy (PDT). In the patient's right eye (OD), OCTA scans demonstrated a large, tangled, and well-demarcated vascular network at the outer retinal (OR) and choriocapillaris (CC) layers. Best-corrected visual acuity (BCVA) was 20/40 OD. Twenty days after PDT, BCVA OD improved (20/30), and the macular hemorrhage was significantly reduced. OCTA showed regression of the vascular network both in the OR and CC layers, with a significant reduction of the internal anastomosis and connection in absence of ischemic complication at the choriocapillaris. The authors concluded that OCTA is the best imaging technique for precise diagnosis and follow-up of the choroidal neovascularization in children affected with BMD. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:969-973.].