Inter-patient variability in response to opioids is well known but a comprehensive definition of its pathophysiological mechanism is still lacking and, more importantly, no studies have focused on children. The STOP Pain project aimed to evaluate the risk factors that contribute to clinical response and adverse drug reactions to opioids by means of a systematic review and a clinical investigation on paediatric oncological patients.

A systematic review of the risk factors for clinical response to opioids for all-age patients with cancer-related pain and presentation of the paediatric STOP pain study / Lucenteforte E.; Vagnoli L.; Pugi A.; Crescioli G.; Lombardi N.; Bonaiuti R.; Arico M.; Giglio S.; Messeri A.; Mugelli A.; Vannacci A.; Maggini V.. - In: BMC CANCER. - ISSN 1471-2407. - ELETTRONICO. - 18:(2018), pp. 568-580. [10.1186/s12885-018-4478-3]

A systematic review of the risk factors for clinical response to opioids for all-age patients with cancer-related pain and presentation of the paediatric STOP pain study

Lucenteforte E.;Crescioli G.;Bonaiuti R.;Giglio S.;Mugelli A.;Vannacci A.;Maggini V.;LOMBARDI, NICCOLO'
2018

Abstract

Inter-patient variability in response to opioids is well known but a comprehensive definition of its pathophysiological mechanism is still lacking and, more importantly, no studies have focused on children. The STOP Pain project aimed to evaluate the risk factors that contribute to clinical response and adverse drug reactions to opioids by means of a systematic review and a clinical investigation on paediatric oncological patients.
2018
18
568
580
Lucenteforte E.; Vagnoli L.; Pugi A.; Crescioli G.; Lombardi N.; Bonaiuti R.; Arico M.; Giglio S.; Messeri A.; Mugelli A.; Vannacci A.; Maggini V....espandi
File in questo prodotto:
File Dimensione Formato  
2018-A systematic review of the risk factors for clinical response to opioids for all-age patients with cancer-related pain and presentation of the paediatric STOP pain study.pdf

accesso aperto

Tipologia: Pdf editoriale (Version of record)
Licenza: Creative commons
Dimensione 733.37 kB
Formato Adobe PDF
733.37 kB Adobe PDF

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1158096
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 12
  • ???jsp.display-item.citation.isi??? 12
social impact