Liposarcoma (LPS) is rare tumor deriving from adipocytes. LPS is classified into histological subtypes: well-differentiated (WDLPS), dedifferentiated (DDLPS), myxoid (MLPS) and pleomorphic (PLPS). A tailored approach taking into account the specificity of disease subtype and age at presentation could be helpful in delineating therapeutic management of liposarcoma. In this paper, we report a retrospective series of a single-institution cohort of patients with LPS, undergoing surgery and radiotherapy and/or chemotherapy. The aim of this study is to evaluate whether clinical characteristics, tumor- and treatment-related features affect clinical outcome in patients treated with curative intent for non-metastatic liposarcoma.
Influence of age and subtype in outcome of operable liposarcoma / Greto, D., Saieva, C., Loi, M., Terziani, F., Visani, L., Garlatti, P., Lo Russo, M., Muntoni, C., Becherini, C., Topulli, J., Campanacci, D., Beltrami, G., Scoccianti, G., Muratori, F., Bonomo, P., Desideri, I., Francolini, G., Livi, L.. - In: LA RADIOLOGIA MEDICA. - ISSN 0033-8362. - STAMPA. - (2019), pp. 290-300. [10.1007/s11547-018-0958-4]
Influence of age and subtype in outcome of operable liposarcoma
Greto, Daniela;Loi, Mauro;Terziani, Francesca;Visani, Luca;Garlatti, Pietro;Lo Russo, Monica;Muntoni, Cristina;Becherini, Carlotta;Campanacci, Domenico;Beltrami, Giovanni;Scoccianti, Guido;Bonomo, Pierluigi;Desideri, Isacco;Francolini, Giulio;Livi, Lorenzo
2019
Abstract
Liposarcoma (LPS) is rare tumor deriving from adipocytes. LPS is classified into histological subtypes: well-differentiated (WDLPS), dedifferentiated (DDLPS), myxoid (MLPS) and pleomorphic (PLPS). A tailored approach taking into account the specificity of disease subtype and age at presentation could be helpful in delineating therapeutic management of liposarcoma. In this paper, we report a retrospective series of a single-institution cohort of patients with LPS, undergoing surgery and radiotherapy and/or chemotherapy. The aim of this study is to evaluate whether clinical characteristics, tumor- and treatment-related features affect clinical outcome in patients treated with curative intent for non-metastatic liposarcoma.
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