Major alterations in the PK/PD of antimicrobial drugs are well documented in critically ill septic patients, but few data are available for the echinocandins. The aims of the present study were: to describe the alterations of caspofungin PK in critically ill septic patients and to carry out a PK/PD analysis in order to assess if the optimal targets are reached
Pharmacokinetic/pharmacodynamic (PK/PD) evaluation of caspofungin in a population of critically ill septic patients / Adembri Chiara, Villa Gianluca, Loriga Beatrice, Novelli Andrea, Rosi Elia, Tofani Lorenzo. - In: EUROPEAN JOURNAL OF ANAESTHESIOLOGY. - ISSN 0265-0215. - STAMPA. - 34:(2017), pp. 313-313.
Pharmacokinetic/pharmacodynamic (PK/PD) evaluation of caspofungin in a population of critically ill septic patients
Adembri Chiara
;Villa Gianluca
;Loriga Beatrice
;Novelli Andrea
;Rosi Elia
;Tofani Lorenzo
2017
Abstract
Major alterations in the PK/PD of antimicrobial drugs are well documented in critically ill septic patients, but few data are available for the echinocandins. The aims of the present study were: to describe the alterations of caspofungin PK in critically ill septic patients and to carry out a PK/PD analysis in order to assess if the optimal targets are reached
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