Investigation of the T-cell receptor (TCR) repertoire in patients with Relapsing-Remitting Multiple Sclerosis (RRMS) before and after two effective immunomodulatory treatments: Natalizumab (NTZ) and autologous hematopoietic stem cell transplantation (AHSCT). The TCR repertoire was investigated on peripheral T-cell subpopulations (naive and memory) by TCRbeta sequencing and, therefore, with high-dimensional bioinformatic analysis.
T-cell response in Relapsing-Remitting Multiple Sclerosis: a computational approach to T-cell receptor repertoire diversity before and during disease-modifying therapies / Roberta Amoriello. - (2020).
T-cell response in Relapsing-Remitting Multiple Sclerosis: a computational approach to T-cell receptor repertoire diversity before and during disease-modifying therapies
Roberta Amoriello
2020
Abstract
Investigation of the T-cell receptor (TCR) repertoire in patients with Relapsing-Remitting Multiple Sclerosis (RRMS) before and after two effective immunomodulatory treatments: Natalizumab (NTZ) and autologous hematopoietic stem cell transplantation (AHSCT). The TCR repertoire was investigated on peripheral T-cell subpopulations (naive and memory) by TCRbeta sequencing and, therefore, with high-dimensional bioinformatic analysis.
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Tesi dottorato Amoriello firmata.pdf
Open Access dal 26/05/2020
Descrizione: tesi di dottorato
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Tesi di dottorato
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9.03 MB
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9.03 MB | Adobe PDF |
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