Depth of invasion (DOI) has been introduced into the latest TNM classification of oral squamous cell carcinoma (OSCC). Despite its primarily pathological definition (pDOI), a preoperative evaluation of a radiological DOI (rDOI) would be useful but a standard and practical definition is lacking. The primary aim of this study is to measure the rDOI by computed tomography (CT) and compare it to the pDOI in a cohort of OSCC patients. Then, we analyze the utility and reliability of rDOI in the preoperative setting.
A critical evaluation of computed tomography-derived depth of invasion in the preoperative assessment of oral cancer staging / Locatello, Luca Giovanni; Bruno, Chiara; Pietragalla, Michele; Taverna, Cecilia; Novelli, Luca; Nardi, Cosimo; Bonasera, Luigi; Cannavicci, Angelo; Maggiore, Giandomenico; Gallo, Oreste. - In: ORAL ONCOLOGY. - ISSN 1368-8375. - STAMPA. - 107:(2020), pp. 104749-104755. [10.1016/j.oraloncology.2020.104749]
A critical evaluation of computed tomography-derived depth of invasion in the preoperative assessment of oral cancer staging
Locatello, Luca Giovanni
;Bruno, Chiara;Pietragalla, Michele;Taverna, Cecilia;Novelli, Luca;Nardi, Cosimo;Bonasera, Luigi;Cannavicci, Angelo;Gallo, Oreste
2020
Abstract
Depth of invasion (DOI) has been introduced into the latest TNM classification of oral squamous cell carcinoma (OSCC). Despite its primarily pathological definition (pDOI), a preoperative evaluation of a radiological DOI (rDOI) would be useful but a standard and practical definition is lacking. The primary aim of this study is to measure the rDOI by computed tomography (CT) and compare it to the pDOI in a cohort of OSCC patients. Then, we analyze the utility and reliability of rDOI in the preoperative setting.
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