Seizure and cognitive outcomes and their predictors were assessed retrospectively in 114 children and 397 adults undergoing temporal lobe epilepsy (TLE) surgery. • Significant differences in several presurgical, surgical, and postsurgical features were observed between children and adults. • Children were more likely to achieve sustained seizure freedom and drug withdrawal after TLE surgery. • Cognitive outcome was best predicted by preoperative performances in either age group. • Early referral should be prompted in order to improve surgical outcomes.
Temporal lobe epilepsy surgery in children and adults: A multicenter study / Barba, Carmen; Cossu, Massimo; Guerrini, Renzo; Di Gennaro, Giancarlo; Villani, Flavio; De Palma, Luca; Grisotto, Laura; Consales, Alessandro; Battaglia, Domenica; Zamponi, Nelia; d’Orio, Piergiorgio; Revay, Martina; Rizzi, Michele; Casciato, Sara; Esposito, Vincenzo; Quarato, Pier Paolo; Di Giacomo, Roberta; Didato, Giuseppe; Pastori, Chiara; Carfi Pavia, Giusy; Pellacani, Simona; Matta, Giulia; Pacetti, Mattia; Tamburrini, Gianpiero; Cesaroni, Elisabetta; Colicchio, Gabriella; Vatti, Giampaolo; Asioli, Sofia; Caulo, Massimo; Marras, Carlo Efisio; Tassi, Laura; Alfredo D'Aniello; Roberta Morace; Marco De Curtis; Francesca Deleo; Flavio Giordano; Alessandro De Benedictis; Giulia Prato; Marco Perulli. - In: EPILEPSIA. - ISSN 0013-9580. - ELETTRONICO. - 62:(2021), pp. 128-142. [10.1111/epi.16772]
Temporal lobe epilepsy surgery in children and adults: A multicenter study
Barba, Carmen
Writing – Original Draft Preparation
;Guerrini, RenzoWriting – Review & Editing
;Grisotto, LauraMethodology
;Matta, GiuliaData Curation
;
2021
Abstract
Seizure and cognitive outcomes and their predictors were assessed retrospectively in 114 children and 397 adults undergoing temporal lobe epilepsy (TLE) surgery. • Significant differences in several presurgical, surgical, and postsurgical features were observed between children and adults. • Children were more likely to achieve sustained seizure freedom and drug withdrawal after TLE surgery. • Cognitive outcome was best predicted by preoperative performances in either age group. • Early referral should be prompted in order to improve surgical outcomes.
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