Cardiovascular disease (CVD) is prevalent in women after menopause, which may be associated with obesity, insulin resistance and metaflammation. Despite the recognized role of immunological mechanisms in vascular remodeling, the role of dendritic cells (DCs) is still unclear. The aim was to characterize monocyte-derived DCs (Mo-DC) in post-menopausal patients with type 2 diabetes (T2DM) and obese woman, without clinical manifestations of atherosclerosis.

Insulin resistance and obesity affect monocyte-derived dendritic cell phenotype and function / Paccosi, Sara; Pala, Laura; Cresci, Barbara; Silvano, Angela; Cecchi, Marta; Caporale, Roberto; Maria Rotella, Carlo; Parenti, Astrid. - In: DIABETES RESEARCH AND CLINICAL PRACTICE. - ISSN 0168-8227. - ELETTRONICO. - 170:(2020), pp. 108528-108536. [10.1016/j.diabres.2020.108528]

Insulin resistance and obesity affect monocyte-derived dendritic cell phenotype and function

Paccosi, Sara
Investigation
;
Pala, Laura
Conceptualization
;
Cresci, Barbara
Conceptualization
;
Silvano, Angela
Investigation
;
Cecchi, Marta
Methodology
;
Caporale, Roberto
Methodology
;
Maria Rotella, Carlo
Supervision
;
Parenti, Astrid
Project Administration
2020

Abstract

Cardiovascular disease (CVD) is prevalent in women after menopause, which may be associated with obesity, insulin resistance and metaflammation. Despite the recognized role of immunological mechanisms in vascular remodeling, the role of dendritic cells (DCs) is still unclear. The aim was to characterize monocyte-derived DCs (Mo-DC) in post-menopausal patients with type 2 diabetes (T2DM) and obese woman, without clinical manifestations of atherosclerosis.
2020
170
108528
108536
Paccosi, Sara; Pala, Laura; Cresci, Barbara; Silvano, Angela; Cecchi, Marta; Caporale, Roberto; Maria Rotella, Carlo; Parenti, Astrid
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1225125
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