Studying multivalent iminosugar glycomimtics to target enzymes for healthcare applications

The main focus of this PhD thesis is the study of iminosugars as potential glycosidases inhibitors. Two main classes of these carbohydrates mimics have been taken into consideration, namely polyhydroxylated pyrrolidines and piperidines, which were treated from different point of view, in particular in terms of Multivalency, one of the main issues studied in this work. If iminosugars is the pivotal class of molecules under deep examination, different types of glycosidases target have been screened, accordingly to the azasugar nature and to the final application consequently.