Aqueductal CSF stroke volume measurements may drive management of shunted idiopathic normal pressure hydrocephalus patients

CSF shunting with adjustable valve is the treatment of idiopathic normal pressure hydrocephalus. The opening pressure valve setting is left to the neurosurgeon’s experience. Aqueductal CSF stroke volume by phase-contrast magnetic resonance measures the CSF passing through the Sylvian aqueduct and it changes with intracranial hydrodynamics. We sought to identify a window of stroke volume differences associated with the best clinical outcome and lowest rate of complications. We concluded that maintainance of stroke volume values within a definite range might help maximize clinical benefit and avoid the risk of CSF overdrainage.