Both our research and that published by Sticchi et al. on immunological memory against hepatitis B virus (HBV) in health-care workers (HCWs) vaccinated as infants or adolescents confirm that in those testing negative after the primary course, one additional (fourth) booster dose is able to elicit an anti-HBs response in >85% subjects. The fifth and the sixth doses further contribute substantially to a high overall response rate. The rate of subjects showing an anamnestic response after the booster dose was almost six-fold higher in HCWs compared to chronic patients. Since universal vaccination in Italy resulted in a significant decrease in HBV infections, special attention and testing should be addressed to those affected by chronic diseases.

Need to take special care of non-responders to hepatitis B vaccination among health-care workers, students and chronic patients / Angela Bechini; Paolo Bonanni; Maddalena Grazzini; Diana Paolini; Giulio Arcangeli; Nicola Mucci; Costanza Bini; Emilia Tiscione; Beatrice Zanella; Sara Boccalini. - In: HUMAN VACCINES & IMMUNOTHERAPEUTICS. - ISSN 2164-5515. - ELETTRONICO. - 17:(2020), pp. 1-3-3. [10.1080/21645515.2020.1810495]

Need to take special care of non-responders to hepatitis B vaccination among health-care workers, students and chronic patients

Angela Bechini;Paolo Bonanni
;
Maddalena Grazzini;Diana Paolini;Giulio Arcangeli;Nicola Mucci;Costanza Bini;Emilia Tiscione;Beatrice Zanella;Sara Boccalini
2020

Abstract

Both our research and that published by Sticchi et al. on immunological memory against hepatitis B virus (HBV) in health-care workers (HCWs) vaccinated as infants or adolescents confirm that in those testing negative after the primary course, one additional (fourth) booster dose is able to elicit an anti-HBs response in >85% subjects. The fifth and the sixth doses further contribute substantially to a high overall response rate. The rate of subjects showing an anamnestic response after the booster dose was almost six-fold higher in HCWs compared to chronic patients. Since universal vaccination in Italy resulted in a significant decrease in HBV infections, special attention and testing should be addressed to those affected by chronic diseases.
2020
17
1-3
3
Angela Bechini; Paolo Bonanni; Maddalena Grazzini; Diana Paolini; Giulio Arcangeli; Nicola Mucci; Costanza Bini; Emilia Tiscione; Beatrice Zanella; Sa...espandi
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1257585
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