Phytotherapy has long been a source of medicinal products and over the years there have been many attempts to use herbal medicines for the treatment of diabetes. Several medicinal plants and their preparations have been demonstrated to act at key points of glucidic metabolism. The most common mechanisms of action found include the inhibition of -glucosidase and of AGE formation, the increase of GLUT-4 and PPARs expression and antioxidant activity. Despite the large amount of literature available, the actual clinical effectiveness of medicinal plants in controlling diabetes-related symptoms remains controversial and there is a crucial need for stronger evidence-based data. In this review, an overview of the medicinal plants, which use in the management of diabetes is supported by authoritative monographs, is provided. References to some species which are currently under increasing clinical investigation are also reported.

Phytotherapy in the Management of Diabetes: A Review / Governa, Paolo; Baini, Giulia; Borgonetti, Vittoria; Cettolin, Giulia; Giachetti, Daniela; Magnano, Anna Rosa; Miraldi, Elisabetta; Biagi, Marco. - In: MOLECULES. - ISSN 1420-3049. - STAMPA. - 23:(2018), pp. 105-125. [10.3390/molecules23010105]

Phytotherapy in the Management of Diabetes: A Review

Borgonetti, Vittoria;
2018

Abstract

Phytotherapy has long been a source of medicinal products and over the years there have been many attempts to use herbal medicines for the treatment of diabetes. Several medicinal plants and their preparations have been demonstrated to act at key points of glucidic metabolism. The most common mechanisms of action found include the inhibition of -glucosidase and of AGE formation, the increase of GLUT-4 and PPARs expression and antioxidant activity. Despite the large amount of literature available, the actual clinical effectiveness of medicinal plants in controlling diabetes-related symptoms remains controversial and there is a crucial need for stronger evidence-based data. In this review, an overview of the medicinal plants, which use in the management of diabetes is supported by authoritative monographs, is provided. References to some species which are currently under increasing clinical investigation are also reported.
2018
23
105
125
Governa, Paolo; Baini, Giulia; Borgonetti, Vittoria; Cettolin, Giulia; Giachetti, Daniela; Magnano, Anna Rosa; Miraldi, Elisabetta; Biagi, Marco
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1281429
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