Autologous hematopoietic stem cell transplantation (AHSCT) induces suppression of clinical-radiological inflammatory activity even in aggressive multiple sclerosis (aMS). However potential neurotoxicity of the procedure, with possible impact on physical and cognitive disability, has recently been suggested. We present a retrospective analysis evaluating the impact of intermediate-intensity AHSCT on cognitive performances in aMS patients treated at the University-Hospital of Careggi in Florence in the period 2016-2020.
Neuropsychological assessment in aggressive multiple sclerosis treated with stem cell transplantation / Mariottini, A; Farina, A; Innocenti, C; Romoli, M; Zilio, I; Azzolini, F; Repice, A; Saccardi, R; Carlucci, G; Massacesi, L. - In: EUROPEAN JOURNAL OF NEUROLOGY. - ISSN 1351-5101. - ELETTRONICO. - 28:(2021), pp. 362-362.
Neuropsychological assessment in aggressive multiple sclerosis treated with stem cell transplantation
Mariottini, A
;Farina, A;Innocenti, C;Romoli, M;Zilio, I;Azzolini, F;Repice, A;Saccardi, R;Carlucci, G;Massacesi, L
2021
Abstract
Autologous hematopoietic stem cell transplantation (AHSCT) induces suppression of clinical-radiological inflammatory activity even in aggressive multiple sclerosis (aMS). However potential neurotoxicity of the procedure, with possible impact on physical and cognitive disability, has recently been suggested. We present a retrospective analysis evaluating the impact of intermediate-intensity AHSCT on cognitive performances in aMS patients treated at the University-Hospital of Careggi in Florence in the period 2016-2020.
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