The principal aim of this PhD thesis is the synthesis of novel N-glycomimetics obtained from simple carbohydrates and from the biomass and, in particular, from levoglucosenone or glucose. The N-glycomimetics which have been synthesized in the course of this work are azasugars, N-glycosides and aminosugars. Biological targets have been identified in two different enzymatic classes: carbonic anhydrases and glycosidases.
Synthesis of nitrogenated glycomimetics from carbohydrates and renewable feedstocks for biomedical applications / Debora Pratesi. - (2023).
Synthesis of nitrogenated glycomimetics from carbohydrates and renewable feedstocks for biomedical applications
Debora Pratesi
2023
Abstract
The principal aim of this PhD thesis is the synthesis of novel N-glycomimetics obtained from simple carbohydrates and from the biomass and, in particular, from levoglucosenone or glucose. The N-glycomimetics which have been synthesized in the course of this work are azasugars, N-glycosides and aminosugars. Biological targets have been identified in two different enzymatic classes: carbonic anhydrases and glycosidases.File in questo prodotto:
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PhD Thesis Debora Pratesi.pdf
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