The use of specific inhibitory drugs of intracellular signalling pathways (such as Bruton-Kinase inhibitors) for the treatment of Waldenstrom's macroglobulinaemia (WM) is a recognised risk factor for Aspergillus spp. infections. The overlapping clinical manifestations of the two diseases may require the involvement of different medical specialities. We describe the clinical course of a patient with pulmonary and encephalic aspergillosis, with concomitant orbital infiltration, which represented a difficult diagnosis: the case required a multidisciplinary approach to define the ocular lesions and an in-depth study of the literature.

Orbital Infiltration in a Patient with Waldenström Macroglobulinemia: Need for Multidisciplinary Approach and Comparison with the Literature / Paggi, Riccardo; Mariotti, Francesca; Mencarini, Jessica; Bresci, Silvia; Campolmi, Irene; Bartalesi, Filippo; Borchi, Beatrice; Nassi, Luca; Sordi, Benedetta; Vannucchi, Alessandro Maria; Bartoloni, Alessandro. - In: MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES. - ISSN 2035-3006. - ELETTRONICO. - 15:(2023), pp. e2023028-0. [10.4084/MJHID.2023.028]

Orbital Infiltration in a Patient with Waldenström Macroglobulinemia: Need for Multidisciplinary Approach and Comparison with the Literature

Paggi, Riccardo
;
Mencarini, Jessica
;
Bresci, Silvia
;
Campolmi, Irene
;
Bartalesi, Filippo
;
Sordi, Benedetta
;
Vannucchi, Alessandro Maria
;
Bartoloni, Alessandro
2023

Abstract

The use of specific inhibitory drugs of intracellular signalling pathways (such as Bruton-Kinase inhibitors) for the treatment of Waldenstrom's macroglobulinaemia (WM) is a recognised risk factor for Aspergillus spp. infections. The overlapping clinical manifestations of the two diseases may require the involvement of different medical specialities. We describe the clinical course of a patient with pulmonary and encephalic aspergillosis, with concomitant orbital infiltration, which represented a difficult diagnosis: the case required a multidisciplinary approach to define the ocular lesions and an in-depth study of the literature.
2023
15
e2023028
0
Paggi, Riccardo; Mariotti, Francesca; Mencarini, Jessica; Bresci, Silvia; Campolmi, Irene; Bartalesi, Filippo; Borchi, Beatrice; Nassi, Luca; Sordi, B...espandi
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1336134
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