We investigated the in vitro and in vivo activities of caspofungin against Aspergillus terreus. The drug increased survival and reduced tissue fungal burden in neutropenic mice. Therefore, our data support the role of caspofungin in treating systemic infections due to this emerging pathogen.
Efficacy of caspofungin against Aspergillus terreus / F.BARCHIESI;E.SPREGHINI;A.SANTINELLI;A.W.FOTHERGILL;S.FALLANI;E.MANSO;E.PISA;D.GIANNINI;A.NOVELLI;M.I.CASSETTA;T.MAZZEI;M.G.RINALDI;G.SCALISE. - In: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. - ISSN 0066-4804. - STAMPA. - 49 (12):(2005), pp. 5133-5135. [10.1128/AAC.49.12.5133-5135.2005]
Efficacy of caspofungin against Aspergillus terreus.
NOVELLI, ANDREA;MAZZEI, TERESITA;
2005
Abstract
We investigated the in vitro and in vivo activities of caspofungin against Aspergillus terreus. The drug increased survival and reduced tissue fungal burden in neutropenic mice. Therefore, our data support the role of caspofungin in treating systemic infections due to this emerging pathogen.
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