Pyridazin-3(2H)-one derivatives of formula (I) are found to inhibit PDE-4; wherein R1, R2 and R4 are organic radicals, R3 is a cyclic group and R5 is an ester or an aryl or heteroaryl group.
Preparation of pyridazin-3(2H)-ones as phosphodiesterase 4 (PDE4) inhibitors / V. DAL PIAZ; AGUILAR IZQUIRDO N; BUIL ALBERO M.A; CARRASCAL RIERA M; GRACIA F; GIOVANNONI M.P; VERGELLI C. - (2004).
Preparation of pyridazin-3(2H)-ones as phosphodiesterase 4 (PDE4) inhibitors
DAL PIAZ, VITTORIO;GIOVANNONI, MARIA PAOLA;VERGELLI, CLAUDIA
2004
Abstract
Pyridazin-3(2H)-one derivatives of formula (I) are found to inhibit PDE-4; wherein R1, R2 and R4 are organic radicals, R3 is a cyclic group and R5 is an ester or an aryl or heteroaryl group.
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