Advanced thyroid carcinoma: an experience of 385 cases..Eur J Surg Onc,..: Jun;32(5):577-582, 2006

Advanced thyroid carcinoma: An experience of 385 cases G. Freschi, L. Landi, A. Castagnoli, A. Taddei, P. Bechi, G. Bucciarelli European Journal of Surgical Oncology (EJSO) Volume 32, Issue 5, Pages 577-582 (June 2006) ABSTRACT Aims To report clinical outcomes of a large series of cases with advanced thyroid cancer. Study design Three hundred and eighty-five patients at the UICC stages III and IV were selected for the study with thyroid cancer. Results Papillary carcinoma and sclerosing carcinoma have better survival than the Hürthle cell and insular types. Lymphatic metastasis does not appear to worsen the prognosis. All the tumour forms offer the chance of long survival. Conclusions Surgical treatment is the primary treatment of thyroid carcinoma. The combined treatments of surgery, metabolic beam therapy, suppressive hormone therapy, radiotherapy and chemotherapy cure a high percentage of patients with the tumour at an advanced stage.