Human serum albumin (HSA) participates in heme scavenging; in turn, heme endows HSA with myoglobin-like reactivity and spectroscopic properties. Here, the allosteric effect of ibuprofen on peroxynitrite isomerization to NO3 catalyzed by ferric human serum heme-albumin (HSA-heme-Fe(III)) is reported.
Ibuprofen impairs allosterically peroxynitrite isomerization by ferric human serum heme-albumin / P. Ascenzi; A. di Masi; M. Coletta; C. Ciaccio; G. Fanali; F.P. Nicoletti; G. Smulevich; and M. Fasano. - In: JOURNAL OF BIOLOGICAL CHEMISTRY. - ISSN 1083-351X. - STAMPA. - 284:(2009), pp. 31006-31017. [10.1074/jbc.M109.010736]
Ibuprofen impairs allosterically peroxynitrite isomerization by ferric human serum heme-albumin.
NICOLETTI, FRANCESCO PAOLO;SMULEVICH, GIULIETTA;
2009
Abstract
Human serum albumin (HSA) participates in heme scavenging; in turn, heme endows HSA with myoglobin-like reactivity and spectroscopic properties. Here, the allosteric effect of ibuprofen on peroxynitrite isomerization to NO3 catalyzed by ferric human serum heme-albumin (HSA-heme-Fe(III)) is reported.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
