In this approach we studied the glycaemia levels in 20 healthy young volunteers (26 2 years), before and after a 30-day intake of 50 mL of extra virgin olive oil (EVOO). We selected an oil rich in phenolic compounds (523 mg/L) with a high content of secoiridoidic derivatives (over 94.5%). The findings from our study reveal a significant decrease of glycaemia from 89.6 6.8 to 82.7 10.3 mg/dL ( p<0.05), related to a long term daily intake of the study EVOO, as the only added fat. A significant increment of the HDL cholesterol, from 68.7 11.5 to 75.2 4.9 mg/dL, was also highlighted. Total cholesterol, LDL, VLDL, triglycerides, and blood pressure did not show significant variation after the 30-day consumption of this EVOO. So far, few articles have described the influence of EVOO consumption, on plasma glucose levels in humans. This effect is observed in a group of healthy young humans. Moreover, we confirm that the level of free hydroxytyrosol (OH-Tyr) in plasma increased up to fourfold ( p<0.05) after the 30-day intake of this EVOO. In addition, the excretion in urine of the main metabolite of OH-Tyr, homovanillic acid (HVA), significantly increased.

Effect of extra virgin olive oil on glycaemia in healthy young subjects / Marıa-Jesus Oliveras-Lopez; Marzia Innocenti; Francisco Martın Bermudo;Herminia Lopez-Garcıa de la Serrana; Nadia Mulinacci. - In: EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY. - ISSN 1438-7697. - ELETTRONICO. - 114:(2012), pp. 999-1006. [10.1002/ejlt.201100368]

Effect of extra virgin olive oil on glycaemia in healthy young subjects

INNOCENTI, MARZIA;MULINACCI, NADIA
2012

Abstract

In this approach we studied the glycaemia levels in 20 healthy young volunteers (26 2 years), before and after a 30-day intake of 50 mL of extra virgin olive oil (EVOO). We selected an oil rich in phenolic compounds (523 mg/L) with a high content of secoiridoidic derivatives (over 94.5%). The findings from our study reveal a significant decrease of glycaemia from 89.6 6.8 to 82.7 10.3 mg/dL ( p<0.05), related to a long term daily intake of the study EVOO, as the only added fat. A significant increment of the HDL cholesterol, from 68.7 11.5 to 75.2 4.9 mg/dL, was also highlighted. Total cholesterol, LDL, VLDL, triglycerides, and blood pressure did not show significant variation after the 30-day consumption of this EVOO. So far, few articles have described the influence of EVOO consumption, on plasma glucose levels in humans. This effect is observed in a group of healthy young humans. Moreover, we confirm that the level of free hydroxytyrosol (OH-Tyr) in plasma increased up to fourfold ( p<0.05) after the 30-day intake of this EVOO. In addition, the excretion in urine of the main metabolite of OH-Tyr, homovanillic acid (HVA), significantly increased.
2012
114
999
1006
Marıa-Jesus Oliveras-Lopez; Marzia Innocenti; Francisco Martın Bermudo;Herminia Lopez-Garcıa de la Serrana; Nadia Mulinacci
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/676846
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