Phosphodiesterases (PDE's) comprise a superfamily of enzymes responsible for the hydrolisis and inactivation of the second messangers cAMP and cGMP.
Pyridazin-3(2H)-one derivatives as novel PDE IV inhibitors / N. Aguilar; J Gràcia; M. Carrascal; V. Dal Piaz; M.P. Giovannoni; C. Vergelli; M. A. Buil; C. Masdeu; Y. Garrido; W. Lumeras; B. Hernandez; M. Cordoba; E. Calaf; M. Andres; M. Miralpeix; A. Gavaldà. - In: DRUGS OF THE FUTURE. - ISSN 0377-8282. - ELETTRONICO. - 34:(2009), pp. 133-133.
Pyridazin-3(2H)-one derivatives as novel PDE IV inhibitors
GIOVANNONI, MARIA PAOLA;VERGELLI, CLAUDIA;
2009
Abstract
Phosphodiesterases (PDE's) comprise a superfamily of enzymes responsible for the hydrolisis and inactivation of the second messangers cAMP and cGMP.
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