Gaertner et al.1 recently reported an elevation of serum antibodies against a mammalian glycosylated myelin-oligodendrocyte-glycoprotein (MOG) in multiple sclerosis (MS). The results emphasize that anti-MOG autoimmunity may be important in monitoring MS. The authors also discuss that the “native” MOG conformation and glycosylation deserve further study and characterization.
Antibodies against glycosylated native MOG are elevated in patients with Multiple Sclerosis / F. LOLLI; P. ROVERO; M. CHELLI; A.M. PAPINI. - In: NEUROLOGY. - ISSN 0028-3878. - STAMPA. - 65:(2005), pp. 781-782. [10.1212/WNL.65.5.781-b]
Antibodies against glycosylated native MOG are elevated in patients with Multiple Sclerosis
LOLLI, FRANCESCO;ROVERO, PAOLO;PAPINI, ANNA MARIA
2005
Abstract
Gaertner et al.1 recently reported an elevation of serum antibodies against a mammalian glycosylated myelin-oligodendrocyte-glycoprotein (MOG) in multiple sclerosis (MS). The results emphasize that anti-MOG autoimmunity may be important in monitoring MS. The authors also discuss that the “native” MOG conformation and glycosylation deserve further study and characterization.
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