This paper shows the advantages of using chemometric strategies in QSAR of NKA analogues containing D-Tryptophan and behaving as highly selective NK-2 receptor antagonists: a) detecting the sequence with optimal antagonist activity, and b) having a strategy for selecting a few most informative sequences. The data set is included on disk as RVD
Chemometric approach to a QSAR study of peptides behaving as NK-2 receptor antagonists / Sergio Clementi; Gabriele Cruciani; Daniela Riganelli; Paolo Rovero; Vittorio Pestellini; Carlo A. Maggi; Massimo Baroni. - In: TETRAHEDRON COMPUTER METHODOLOGY. - ISSN 0898-5529. - STAMPA. - 3 (6 PART B):(1990), pp. 379-387.
Chemometric approach to a QSAR study of peptides behaving as NK-2 receptor antagonists
ROVERO, PAOLO;
1990
Abstract
This paper shows the advantages of using chemometric strategies in QSAR of NKA analogues containing D-Tryptophan and behaving as highly selective NK-2 receptor antagonists: a) detecting the sequence with optimal antagonist activity, and b) having a strategy for selecting a few most informative sequences. The data set is included on disk as RVD
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