DI CESARE MANNELLI, LORENZO
DI CESARE MANNELLI, LORENZO
Neuroscienze, Psicologia, Area del Farmaco e Salute del Bambino (NEUROFARBA)
(E)-3-Furan-2-yl- N- p-tolyl-acrylamide and its Derivative DM489 Decrease Neuropathic Pain in Mice Predominantly by α7 Nicotinic Acetylcholine Receptor Potentiation
2020 Arias H.R.; Ghelardini C.; Lucarini E.; Tae H.-S.; Yousuf A.; Marcovich I.; Manetti D.; Romanelli M.N.; Elgoyhen A.B.; Adams D.J.; Di Cesare Mannelli L.
1H NMR and HPLC-DAD-MS for the characterization of ellagitannins and triterpenoids of less investigated Anogeissus leiocarpus DC (Combretaceae) stem bark
2022 Akande, Titilayo; Khatib, Mohamad; Ola Salawu, Sule; Afolabi Akindahunsi, Akintunde; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Balli, Diletta; Cecchi, Lorenzo; Mulinacci, Nadia
2- or 3-Substituted piperazines as nootropic agents: carbethoxy and hydroxymethyl analogues of the cognition-enhancer DM235
2015 Martino, M. V.; DI CESARE MANNELLI, L. ; Bartolucci, G.; S, . DEI; Manetti, D.; Ghelardini, C.; Teodori, E.; Romanelli, M. N.
2-Arylpyrazolo[4,3-d]pyrimidin-7-amino Derivatives As New Potent and Selective Human A3Adenosine Receptor Antagonists. Molecular Modeling Studies and Pharmacological Evaluation
2013 Lucia Squarcialupi;Vittoria Colotta;Daniela Catarzi;Flavia Varano;Guido Filacchioni;Katia Varani;Carmen Corciulo;Fabrizio Vincenzi;Pier Andrea Borea;Carla Ghelardini;Lorenzo Di Cesare Mannelli;Antonella Ciancetta;Stefano Moro
2-Arylpyrazolo[4,3-d]pyrimidin-7-amino derivatives, new potent and selective human A3 adenosine receptor antagonists endowed with protective effect against oxaliplatin-induced apoptosis in rat astrocyte cell cultures
2012 V. Colotta; L. Squarcialupi; D. Catarzi; F. Varano; K. Varani; F. Vincenzi; M. Zanardelli; L. Di Cesare Mannelli; C. Ghelardini; S. Paoletta; S. Moro
3-Hydroxy-1H-quinazoline-2,4-dione as a New Scaffold to Develop Potent and Selective Inhibitors of the Tumor-Associated Carbonic Anhydrases IX and XII
2017 Falsini, Matteo; Squarcialupi, Lucia; Catarzi, Daniela; Varano, Flavia; Betti, Marco; Di Cesare Mannelli, Lorenzo; Tenci, Barbara; Ghelardini, Carla; Tanc, Muhammet; Angeli, Andrea; Supuran, Claudiu T.; Colotta, Vittoria
3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new potent and selective inhibitors of the tumor-associated carbonic anhydrase IX and XII.
2015 Squarcialupi, L.; Falsini, M.; Catarzi, D.; Varano, F.; Betti, M.; Di Cesare Mannelli, L.; Zanardelli, M.; Ghelardini, C.; Tanc, M.; Supuran, C.T.; Colotta, V.
4-Hydroxy-3-nitro-5-ureido-benzenesulfonamides selectively target the tumor-associated carbonic anhydrase isoforms IX and XII showing hypoxia-enhanced anti-proliferative profiles.
2018 Nocentini A, Trallori E, Singh S, Lomelino CL, Bartolucci G, Di Cesare Mannelli L, Ghelardini C, McKenna R, Gratteri P, Supuran CT
6-substituted sulfocoumarins are selective carbonic anhdydrase IX and XII Inhibitors with significant cytotoxicity against colorectal cancer cells
2015 Grandane, Aiga; Tanc, Muhammet; Di Cesare Mannelli, Lorenzo; Carta, Fabrizio; Ghelardini, Carla; Žalubovskis, Raivis; Supuran, Claudiu T.
[35S]GTPgammaS binding studies of amphiphilic drugs-activated Gi proteins: A caveat
2009 Dina Manetti; Lorenzo Di Cesare Mannelli; Silvia Dei; Luca Guandalini; Elisabetta Martini; Martina Banchelli; Carla Ghelardini
A class of pyrrole derivatives endowed with analgesic/anti- inflammatory activity
2013 Battilocchio C; Poce G; Alfonso S; Porretta GC; Consalvi S; Sautebin L; Pace S; Rossi A; Ghelardini C; Di Cesare Mannelli L; Schenone S; Giordani A; Di Francesco L; Patrignani P; Biava M
A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects
2015 Carta, Fabrizio; Di Cesare Mannelli, Lorenzo; Pinard, Melissa; Ghelardini, Carla; Scozzafava, Andrea; Mckenna, Robert; Supuran, Claudiu T.
A model of neuropathic pain induced by sorafenib in the rat: Effect of dimiracetam
2015 Di Cesare Mannelli, Lorenzo; Maresca, Mario; Farina, Carlo; Scherz, Michael W; Ghelardini, Carla
A novel manganese complex effective as superoxide anion scavenger and therapeutic agent against cell and tissue oxidative injury.
2009 Failli P; Bani D; Cantore M; Di Cesare Mannelli L; Ghelardini C; Giorgi C; Innocenti M; Udisti R; Rugi F; Spepi A;Valtancoli B; Bencini A.
A rat model of FOLFOX-induced neuropathy: effects of oral dimiracetam in comparison with duloxetine and pregabalin
2017 Lorenzo Di Cesare Mannelli, ; Mario, Maresca; Laura, Micheli; Carlo, Farina; Michael, W; Carla, Ghelardini
A recombinant transductor-effector system: in vitro study of G inhibitor protein (G-alfa-i1)direct activators
2006 L. DI CESARE MANNELLI; A. PACINI; A. TOSCANO; C. GHELARDINI; D. MANETTI; F. GUALTIERI; T. PATEL; A. BARTOLINI
A Series of COX-2 Inhibitors Endowed with NO-Releasing Properties: Synthesis, Biological Evaluation, and Docking Analysis
2016 Consalvi, Sara; Poce, Giovanna; Ragno, Rino; Sabatino, Manuela; Lamotta, Concettina; Sartini, Stefania; Calderone, Vincenzo; Martelli, Alma; Ghelardini, Carla; DI CESARE MANNELLI, Lorenzo; Biava, Mariangela
A Smart Platform for Hyperthermia Application in Cancer Treatment: Cobalt-Doped Ferrite Nanoparticles Mineralized in Human Ferritin Cages
2014 Elvira Fantechi;Claudia Innocenti;Matteo Zanardelli;Maria Fittipaldi;Elisabetta Falvo;Miriam Carbo;Valbona Shullani;Lorenzo Di Cesare Mannelli;Carla Ghelardini;Anna Maria Ferretti;Alessandro Ponti;Claudio Sangregorio;Pierpaolo Ceci
A TRPA1 antagonist reverts oxaliplatin-induced neuropathic pain
2013 Nativi, Cristina; Gualdani, R; Dragoni, Elisa; DI CESARE MANNELLI, Lorenzo; Sostegni, S; Norcini, M; Gabrielli, G; LA MARCA, Giancarlo; Richichi, Barbara; Francesconi, Oscar; Moncelli, MARIA ROSA; Ghelardini, Carla; Roelens, Stefano
Acetyl-L-carnitine increases artemin level and prevents neurotrophic factor alterations during neuropathy
2010 Vivoli E; Di Cesare Mannelli L; Salvicchi A; Bartolini A; Koverech A; nicolai R; Benatti P; Ghelardini C
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
(E)-3-Furan-2-yl- N- p-tolyl-acrylamide and its Derivative DM489 Decrease Neuropathic Pain in Mice Predominantly by α7 Nicotinic Acetylcholine Receptor Potentiation | 2020 | Arias H.R.; Ghelardini C.; Lucarini E.; Tae H.-S.; Yousuf A.; Marcovich I.; Manetti D.; Romanelli M.N.; Elgoyhen A.B.; Adams D.J.; Di Cesare Mannelli L. | |
1H NMR and HPLC-DAD-MS for the characterization of ellagitannins and triterpenoids of less investigated Anogeissus leiocarpus DC (Combretaceae) stem bark | 2022 | Akande, Titilayo; Khatib, Mohamad; Ola Salawu, Sule; Afolabi Akindahunsi, Akintunde; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Balli, Diletta; Cecchi, Lorenzo; Mulinacci, Nadia | |
2- or 3-Substituted piperazines as nootropic agents: carbethoxy and hydroxymethyl analogues of the cognition-enhancer DM235 | 2015 | Martino, M. V.; DI CESARE MANNELLI, L. ; Bartolucci, G.; S, . DEI; Manetti, D.; Ghelardini, C.; Teodori, E.; Romanelli, M. N. | |
2-Arylpyrazolo[4,3-d]pyrimidin-7-amino Derivatives As New Potent and Selective Human A3Adenosine Receptor Antagonists. Molecular Modeling Studies and Pharmacological Evaluation | 2013 | Lucia Squarcialupi;Vittoria Colotta;Daniela Catarzi;Flavia Varano;Guido Filacchioni;Katia Varani;Carmen Corciulo;Fabrizio Vincenzi;Pier Andrea Borea;Carla Ghelardini;Lorenzo Di Cesare Mannelli;Antonella Ciancetta;Stefano Moro | |
2-Arylpyrazolo[4,3-d]pyrimidin-7-amino derivatives, new potent and selective human A3 adenosine receptor antagonists endowed with protective effect against oxaliplatin-induced apoptosis in rat astrocyte cell cultures | 2012 | V. Colotta; L. Squarcialupi; D. Catarzi; F. Varano; K. Varani; F. Vincenzi; M. Zanardelli; L. Di Cesare Mannelli; C. Ghelardini; S. Paoletta; S. Moro | |
3-Hydroxy-1H-quinazoline-2,4-dione as a New Scaffold to Develop Potent and Selective Inhibitors of the Tumor-Associated Carbonic Anhydrases IX and XII | 2017 | Falsini, Matteo; Squarcialupi, Lucia; Catarzi, Daniela; Varano, Flavia; Betti, Marco; Di Cesare Mannelli, Lorenzo; Tenci, Barbara; Ghelardini, Carla; Tanc, Muhammet; Angeli, Andrea; Supuran, Claudiu T.; Colotta, Vittoria | |
3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new potent and selective inhibitors of the tumor-associated carbonic anhydrase IX and XII. | 2015 | Squarcialupi, L.; Falsini, M.; Catarzi, D.; Varano, F.; Betti, M.; Di Cesare Mannelli, L.; Zanardelli, M.; Ghelardini, C.; Tanc, M.; Supuran, C.T.; Colotta, V. | |
4-Hydroxy-3-nitro-5-ureido-benzenesulfonamides selectively target the tumor-associated carbonic anhydrase isoforms IX and XII showing hypoxia-enhanced anti-proliferative profiles. | 2018 | Nocentini A, Trallori E, Singh S, Lomelino CL, Bartolucci G, Di Cesare Mannelli L, Ghelardini C, McKenna R, Gratteri P, Supuran CT | |
6-substituted sulfocoumarins are selective carbonic anhdydrase IX and XII Inhibitors with significant cytotoxicity against colorectal cancer cells | 2015 | Grandane, Aiga; Tanc, Muhammet; Di Cesare Mannelli, Lorenzo; Carta, Fabrizio; Ghelardini, Carla; Žalubovskis, Raivis; Supuran, Claudiu T. | |
[35S]GTPgammaS binding studies of amphiphilic drugs-activated Gi proteins: A caveat | 2009 | Dina Manetti; Lorenzo Di Cesare Mannelli; Silvia Dei; Luca Guandalini; Elisabetta Martini; Martina Banchelli; Carla Ghelardini | |
A class of pyrrole derivatives endowed with analgesic/anti- inflammatory activity | 2013 | Battilocchio C; Poce G; Alfonso S; Porretta GC; Consalvi S; Sautebin L; Pace S; Rossi A; Ghelardini C; Di Cesare Mannelli L; Schenone S; Giordani A; Di Francesco L; Patrignani P; Biava M | |
A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects | 2015 | Carta, Fabrizio; Di Cesare Mannelli, Lorenzo; Pinard, Melissa; Ghelardini, Carla; Scozzafava, Andrea; Mckenna, Robert; Supuran, Claudiu T. | |
A model of neuropathic pain induced by sorafenib in the rat: Effect of dimiracetam | 2015 | Di Cesare Mannelli, Lorenzo; Maresca, Mario; Farina, Carlo; Scherz, Michael W; Ghelardini, Carla | |
A novel manganese complex effective as superoxide anion scavenger and therapeutic agent against cell and tissue oxidative injury. | 2009 | Failli P; Bani D; Cantore M; Di Cesare Mannelli L; Ghelardini C; Giorgi C; Innocenti M; Udisti R; Rugi F; Spepi A;Valtancoli B; Bencini A. | |
A rat model of FOLFOX-induced neuropathy: effects of oral dimiracetam in comparison with duloxetine and pregabalin | 2017 | Lorenzo Di Cesare Mannelli, ; Mario, Maresca; Laura, Micheli; Carlo, Farina; Michael, W; Carla, Ghelardini | |
A recombinant transductor-effector system: in vitro study of G inhibitor protein (G-alfa-i1)direct activators | 2006 | L. DI CESARE MANNELLI; A. PACINI; A. TOSCANO; C. GHELARDINI; D. MANETTI; F. GUALTIERI; T. PATEL; A. BARTOLINI | |
A Series of COX-2 Inhibitors Endowed with NO-Releasing Properties: Synthesis, Biological Evaluation, and Docking Analysis | 2016 | Consalvi, Sara; Poce, Giovanna; Ragno, Rino; Sabatino, Manuela; Lamotta, Concettina; Sartini, Stefania; Calderone, Vincenzo; Martelli, Alma; Ghelardini, Carla; DI CESARE MANNELLI, Lorenzo; Biava, Mariangela | |
A Smart Platform for Hyperthermia Application in Cancer Treatment: Cobalt-Doped Ferrite Nanoparticles Mineralized in Human Ferritin Cages | 2014 | Elvira Fantechi;Claudia Innocenti;Matteo Zanardelli;Maria Fittipaldi;Elisabetta Falvo;Miriam Carbo;Valbona Shullani;Lorenzo Di Cesare Mannelli;Carla Ghelardini;Anna Maria Ferretti;Alessandro Ponti;Claudio Sangregorio;Pierpaolo Ceci | |
A TRPA1 antagonist reverts oxaliplatin-induced neuropathic pain | 2013 | Nativi, Cristina; Gualdani, R; Dragoni, Elisa; DI CESARE MANNELLI, Lorenzo; Sostegni, S; Norcini, M; Gabrielli, G; LA MARCA, Giancarlo; Richichi, Barbara; Francesconi, Oscar; Moncelli, MARIA ROSA; Ghelardini, Carla; Roelens, Stefano | |
Acetyl-L-carnitine increases artemin level and prevents neurotrophic factor alterations during neuropathy | 2010 | Vivoli E; Di Cesare Mannelli L; Salvicchi A; Bartolini A; Koverech A; nicolai R; Benatti P; Ghelardini C |