| Nome |
# |
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Local anaesthetic activity of beta-caryophyllene., file e398c378-b1b4-179a-e053-3705fe0a4cff
|
1.762
|
|
Acute effect of Capparis spinosa root extracts on rat articular pain, file e398c37a-eb0a-179a-e053-3705fe0a4cff
|
1.025
|
|
Development of solid lipid nanoparticles as carriers for improving oral bioavailability of glibenclamide, file e398c37a-f859-179a-e053-3705fe0a4cff
|
970
|
|
Bacopa monnieri as augmentation therapy in the treatment of anhedonia, preclinical and clinical evaluation, file e398c37f-fc6f-179a-e053-3705fe0a4cff
|
906
|
|
LOCAL ANAESTHETIC ACTIVITY OF (+) AND (-) MENTHOL, file e398c378-8436-179a-e053-3705fe0a4cff
|
799
|
|
Effects of natural and synthetic isothiocyanate-based H2S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels, file e398c37c-97e5-179a-e053-3705fe0a4cff
|
616
|
|
Anticancer properties of erucin, an H2 S-releasing isothiocyanate, on human pancreatic adenocarcinoma cells (AsPC-1)., file e398c37e-e71c-179a-e053-3705fe0a4cff
|
592
|
|
Antineuropathic profile of N-palmitoylethanolamine in a rat model of oxaliplatin-induced neurotoxicity, file e398c37b-0d27-179a-e053-3705fe0a4cff
|
571
|
|
Selective HCN1 block as a strategy to control oxaliplatin-induced neuropathy, file e398c37c-aeb0-179a-e053-3705fe0a4cff
|
531
|
|
Oxaliplatin-induced neuropathy: oxidative stress as pathological mechanism. Protective effect of silibinin, file e398c378-d71c-179a-e053-3705fe0a4cff
|
530
|
|
Effect of glucoraphanin and sulforaphane against chemotherapy-induced neuropathic pain: Kv7 potassium channels modulation by H2 S release in vivo., file e398c37d-c87e-179a-e053-3705fe0a4cff
|
528
|
|
α2 Adrenoceptor: a Target for Neuropathic Pain Treatment, file e398c37a-ecee-179a-e053-3705fe0a4cff
|
526
|
|
A rat model of FOLFOX-induced neuropathy: effects of oral dimiracetam in comparison with duloxetine and pregabalin, file e398c37c-9316-179a-e053-3705fe0a4cff
|
520
|
|
Synthesis and Biological Evaluation of Novel Neuroprotective Pyridazine Derivatives as Excitatory Amino Acid Transporter 2 (EAAT2) Activators, file e398c37c-d047-179a-e053-3705fe0a4cff
|
516
|
|
Effects of a water extract of Lepidium meyenii root in different models of persistent pain in rats, file e398c37c-9682-179a-e053-3705fe0a4cff
|
488
|
|
Adipose-derived stem cells decrease pain in a rat model of oxaliplatin-induced neuropathy: Role of VEGF-A modulation, file e398c37c-9538-179a-e053-3705fe0a4cff
|
480
|
|
The novel H2S-donor 4-carboxyphenyl isothiocyanate promotes cardioprotective effects against ischemia/reperfusion injury through activation of mitoKATP channels and reduction of oxidative stress, file e398c37a-e568-179a-e053-3705fe0a4cff
|
466
|
|
Eruca sativa Mill. seed extract promotes anti-obesity and hypoglycemic effects in mice fed with a high-fat diet, file e398c380-84c2-179a-e053-3705fe0a4cff
|
455
|
|
Photobiomodulation therapy by NIR laser in persistent pain: an analytical study in the rat, file e398c37c-d044-179a-e053-3705fe0a4cff
|
448
|
|
Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors, file e398c37c-a8c8-179a-e053-3705fe0a4cff
|
444
|
|
Identification of the First Synthetic Allosteric Modulator of the CB2 Receptors and Evidence of Its Efficacy for Neuropathic Pain Relief, file e398c37d-af7d-179a-e053-3705fe0a4cff
|
444
|
|
Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors, file e398c37a-fc50-179a-e053-3705fe0a4cff
|
429
|
|
Effects of Hypericum perforatum extract on oxaliplatin-induced neurotoxicity: in vitro evaluations, file e398c37c-929c-179a-e053-3705fe0a4cff
|
419
|
|
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues, file e398c37b-218e-179a-e053-3705fe0a4cff
|
418
|
|
A Series of COX-2 Inhibitors Endowed with NO-Releasing Properties: Synthesis, Biological Evaluation, and Docking Analysis, file e398c37b-2060-179a-e053-3705fe0a4cff
|
368
|
|
Erucin exhibits vasorelaxing effects and antihypertensive activity by H2 S-releasing properties, file e398c37e-e719-179a-e053-3705fe0a4cff
|
350
|
|
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain, file e398c37d-c87d-179a-e053-3705fe0a4cff
|
349
|
|
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain, file e398c37a-f8d2-179a-e053-3705fe0a4cff
|
333
|
|
Synthesis, biological evaluation and molecular modeling of novel selective COX-2 inhibitors: sulfide, sulfoxide, and sulfone derivatives of 1,5-diarylpyrrol-3-substituted scaffold, file e398c37e-879b-179a-e053-3705fe0a4cff
|
333
|
|
Acute visceral pain relief mediated by A(3)AR agonists in rats: involvement of N-type voltage-gated calcium channels, file e398c380-1a49-179a-e053-3705fe0a4cff
|
321
|
|
Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors, file e398c37a-fb47-179a-e053-3705fe0a4cff
|
315
|
|
Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity, file e398c37a-f99a-179a-e053-3705fe0a4cff
|
311
|
|
Calcium alginate microspheres containing metformin hydrochloride niosomes and chitosomes aimed for oral therapy of type 2 diabetes mellitus, file e398c37c-c482-179a-e053-3705fe0a4cff
|
310
|
|
Involvement of the N/OFQ-NOP system in rat morphine antinociceptive tolerance: Are astrocytes the crossroad?, file e398c37c-c98c-179a-e053-3705fe0a4cff
|
302
|
|
Acute and subchronic antinociceptive effects of nociceptin/orphanin FQ receptor agonists infused by intrathecal route in rats, file e398c37a-f81e-179a-e053-3705fe0a4cff
|
283
|
|
Aminopyrrolic synthetic receptors for monosaccharides: A class of carbohydrate-binding agents endowed with antibiotic activity versus pathogenic yeasts, file e398c378-ca5c-179a-e053-3705fe0a4cff
|
280
|
|
The Versatile 2-Substituted Imidazoline Nucleus as a Structural Motif of Ligands Directed to the Serotonin 5-HT1A Receptor, file e398c37a-ef8f-179a-e053-3705fe0a4cff
|
280
|
|
TREATMENT WITH ACETYL-L-CARNITINE EXERTS A NEUROPROTECTIVE EFFECT IN THE SCIATIC NERVE FOLLOWING LOOSE LIGATION: A FUNCTIONAL AND MICROANATOMICAL STUDY, file e398c37d-a05b-179a-e053-3705fe0a4cff
|
278
|
|
The active second-generation proteasome inhibitor oprozomib reverts the oxaliplatin-induced neuropathy symptoms, file e398c380-271b-179a-e053-3705fe0a4cff
|
274
|
|
Design, synthesis and X-ray crystallography of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects., file e398c37d-b0ce-179a-e053-3705fe0a4cff
|
273
|
|
Coronaridine congeners decrease neuropathic pain in mice and inhibit α9α10 nicotinic acetylcholine receptors and CaV2.2 channels, file e398c380-2726-179a-e053-3705fe0a4cff
|
271
|
|
Therapeutic potential for coxibs-nitric oxide releasing hybrids in cystic fibrosis, file e398c380-451c-179a-e053-3705fe0a4cff
|
266
|
|
RELAXANT EFFECT OF A WATER SOLUBLE CARBON MONOXIDE-RELEASING MOLECULE (CORM-3) ON SPONTANEOUSLY HYPERTENSIVE RAT AORTAS, file e398c378-d71b-179a-e053-3705fe0a4cff
|
261
|
|
(E)-3-Furan-2-yl- N- p-tolyl-acrylamide and its Derivative DM489 Decrease Neuropathic Pain in Mice Predominantly by α7 Nicotinic Acetylcholine Receptor Potentiation, file e398c380-451e-179a-e053-3705fe0a4cff
|
259
|
|
Neuropathy-induced apoptosis: Protective effect of physostigmine, file e398c37a-fbc8-179a-e053-3705fe0a4cff
|
250
|
|
Tanshinones from Salvia miltiorrhiza Bunge revert chemotherapy-induced neuropathic pain and reduce glioblastoma cells malignancy, file e398c37d-c880-179a-e053-3705fe0a4cff
|
249
|
|
Effect of treatment with the antioxidant alpha-lipoic (thioctic) acid on heart and kidney microvasculature in spontaneously hypertensive rats, file e398c37b-0391-179a-e053-3705fe0a4cff
|
241
|
|
A novel manganese complex effective as superoxide anion scavenger and therapeutic agent against cell and tissue oxidative injury., file e398c378-a136-179a-e053-3705fe0a4cff
|
235
|
|
BDNF and ARTEMIN are increased in drug-naïve non-depressed GAD patients: Preliminary data, file e398c37a-f909-179a-e053-3705fe0a4cff
|
232
|
|
Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX), file e398c380-cf03-179a-e053-3705fe0a4cff
|
231
|
|
Intra-articular mucilages: behavioural and histological evaluations for a new model of articular pain., file e398c37e-df25-179a-e053-3705fe0a4cff
|
228
|
|
Atomoxetine for hoarding disorder: A pre-clinical and clinical investigation, file e398c37a-eee1-179a-e053-3705fe0a4cff
|
226
|
|
Heterocoumarins Are Selective Carbonic Anhydrase IX and XII Inhibitors with Cytotoxic Effects against Cancer Cells Lines, file e398c37d-6ca7-179a-e053-3705fe0a4cff
|
220
|
|
Phaseolus vulgaris L. Extract: Alpha-Amylase Inhibition against Metabolic Syndrome in Mice ., file e398c37e-8426-179a-e053-3705fe0a4cff
|
219
|
|
Synthesis and pharmacological evaluation of novel GABAA subtype receptor ligands with potential anxiolytic-like and anti-hyperlagesic effect, file e398c37b-b68d-179a-e053-3705fe0a4cff
|
218
|
|
Synergic stimulation of serotonin 5-HT1A receptor and α2-adrenoceptors for neuropathic pain relief: Preclinical effects of 2-substituted imidazoline derivatives, file e398c37c-d046-179a-e053-3705fe0a4cff
|
215
|
|
The pharmacological basis of opioids, file e398c37a-f5b0-179a-e053-3705fe0a4cff
|
213
|
|
Delay of morphine tolerance by palmitoylethanolamide, file e398c37a-f8d7-179a-e053-3705fe0a4cff
|
208
|
|
Design, characterization and in vivo evaluation of nanostructured lipid carriers (NLC) as a new drug delivery system for hydrochlorothiazide oral administration in pediatric therapy, file e398c37d-7590-179a-e053-3705fe0a4cff
|
208
|
|
Anti-neuropathic effects of Rosmarinus officinalis L. terpenoid fraction: Relevance of nicotinic receptors, file e398c37a-ed05-179a-e053-3705fe0a4cff
|
186
|
|
PPAR-γ Impairment Alters Peroxisome Functionality in Primary Astrocyte Cell Cultures, file e398c37a-2777-179a-e053-3705fe0a4cff
|
179
|
|
ANTINOCICEPTIVE PROFILE OF THE NATURAL CHOLINESTERASE INHIBITOR HUPERZINE A, file e398c378-8433-179a-e053-3705fe0a4cff
|
177
|
|
Pain relieving and protective effects of Astragalus hydroalcoholic extract in rat arthritis models, file e398c37c-bc83-179a-e053-3705fe0a4cff
|
174
|
|
Effect of the SOD mimetic MnL4 on in vitro and in vivo oxaliplatin toxicity: Possible aid in chemotherapy induced neuropathy, file e398c37a-279f-179a-e053-3705fe0a4cff
|
173
|
|
Prophylactic versus Therapeutic Fingolimod: Restoration of Presynaptic Defects in Mice Suffering from Experimental Autoimmune Encephalomyelitis, file e398c37c-ed85-179a-e053-3705fe0a4cff
|
172
|
|
Effects of Ultramicronized N-Palmitoylethanolamine Supplementation on Tramadol and Oxycodone Analgesia and Tolerance Prevention, file e398c381-e57a-179a-e053-3705fe0a4cff
|
171
|
|
Design, Synthesis, and X-ray of Selenides as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology, file e398c37d-6ae5-179a-e053-3705fe0a4cff
|
168
|
|
Apoptotic Process Induced by Oxaliplatin in Rat Hippocampus Causes Memory Impairment, file e398c37a-ec4b-179a-e053-3705fe0a4cff
|
163
|
|
Combined Approach of Cyclodextrin Complexation and Nanostructured Lipid Carriers for the Development of a Pediatric Liquid Oral Dosage Form of Hydrochlorothiazide, file e398c37e-05b4-179a-e053-3705fe0a4cff
|
154
|
|
AG-4:A NICOTINIC AGONIST ENDOWED WITH ANTIAMNESIC PROPERTIES, file e398c378-9d5c-179a-e053-3705fe0a4cff
|
153
|
|
Astragali radix: could it be an adjuvant for oxaliplatin-induced neuropathy?, file e398c37b-a043-179a-e053-3705fe0a4cff
|
149
|
|
Neuroprotective activity of thioctic acid in central nervous system lesions consequent to peripheral nerve injury., file e398c378-f0c9-179a-e053-3705fe0a4cff
|
144
|
|
Oxaliplatin Neurotoxicity Involves Peroxisome Alterations. PPARc Agonism as Preventive Pharmacological Approach, file e398c378-82d7-179a-e053-3705fe0a4cff
|
143
|
|
Characterisation of the novel mixed Mu-NOP peptide ligand dermorphin-N/OFQ (DeNo), file e398c37a-ec4e-179a-e053-3705fe0a4cff
|
131
|
|
Pretreatment with relaxin does not restore no-mediated modulation of calcium signal in coronary endothelial cells isolated from spontaneously hypertensive rats, file e398c379-f2a7-179a-e053-3705fe0a4cff
|
126
|
|
GLUTAMATERGIC SYSTEM MODULATORS AS AGENTS IN PREVENTION AND MANAGEMENT OF CHEMOTHERAPY- INDUCED POLYNEUROPATHY, file e398c37a-f7c8-179a-e053-3705fe0a4cff
|
124
|
|
OXALIPLATIN-INDUCED BLOOD BRAIN BARRIER LOOSENING: A NEW POINT OF VIEW ON CHEMOTHERAPY-INDUCED NEUROTOXICITY, file e398c37d-89b0-179a-e053-3705fe0a4cff
|
122
|
|
Effects of Cadmium on ZO-1 Tight Junction Integrity of the Blood Brain Barrier., file e398c37f-4822-179a-e053-3705fe0a4cff
|
122
|
|
Analgesic and antineuropathic drugs acting through central cholinergic mechanisms, file e398c37a-fe04-179a-e053-3705fe0a4cff
|
121
|
|
Therapeutic Effects of the Superoxide Dismutase Mimetic Compound Mn(II)Me2DO2A on Experimental Articular Pain in Rats., file e398c378-e50c-179a-e053-3705fe0a4cff
|
119
|
|
Development of ligands at gamma aminobutyrric acid type A (GABAA) receptor subtype as new agent for pain relief., file e398c379-b1e5-179a-e053-3705fe0a4cff
|
115
|
|
α7 Nicotinic Receptor Promotes the Neuroprotective Functions of Astrocytes against Oxaliplatin Neurotoxicity, file e398c379-b516-179a-e053-3705fe0a4cff
|
114
|
|
Effect of Vitis vinifera hydroalcoholic extract against oxaliplatin neurotoxicity: in vitro and in vivo evidence, file e398c37d-89b3-179a-e053-3705fe0a4cff
|
114
|
|
The Role of TRPA1 and TRPV1 Channels in Orofacial Pain, file e398c37b-4afb-179a-e053-3705fe0a4cff
|
111
|
|
Pretreatment with Relaxin Does Not Restore NO-Mediated Modulation of Calcium Signal in Coronary Endothelial Cells Isolated from Spontaneously Hypertensive Rats, file e398c37a-8894-179a-e053-3705fe0a4cff
|
108
|
|
Low dose native type II collagen prevents pain in a rat osteoarthritis model, file e398c378-f4ef-179a-e053-3705fe0a4cff
|
107
|
|
Mesenchymal stem cells, implications for pain therapy., file e398c37e-dd4a-179a-e053-3705fe0a4cff
|
107
|
|
Different apoptotic pathways activated by oxaliplatin in primary astrocytes vs. colo-rectal cancer cells, file e398c37a-fb45-179a-e053-3705fe0a4cff
|
106
|
|
Brain activity of thioctic Acid enantiomers: in vitro and in vivo studies in an animal model of cerebrovascular injury, file e398c37b-296e-179a-e053-3705fe0a4cff
|
105
|
|
Improving the therapeutic efficacy of prilocaine by PLGA microparticles: Preparation, characterization and in vivo evaluation., file e398c37d-919d-179a-e053-3705fe0a4cff
|
104
|
|
Eruca sativa Meal against Diabetic Neuropathic Pain: An H2S-Mediated Effect of Glucoerucin, file e398c37e-8798-179a-e053-3705fe0a4cff
|
103
|
|
Synthesis of novel cognition enhancer with pyrazolo[5,1-c][1,2,4]benzotriazine core acting at gamma-aminobutyric acid type A (GABAA) receptor., file e398c379-b1e7-179a-e053-3705fe0a4cff
|
102
|
|
Palmitoylthanolamide is a disease-modifying agent in peripheral neuropathy: pain relief and neuroprotection share a PPAR-apha-mediated mechanism., file e398c378-f0b8-179a-e053-3705fe0a4cff
|
101
|
|
Synthesis of five and six-membered heterocycles bearing an arylpiperazinylalkyl side chain as orally active antinociceptive agents, file e398c380-8a2a-179a-e053-3705fe0a4cff
|
101
|
|
Pain Relieving and Neuroprotective Effects of Non-opioid Compound, DDD-028, in the Rat Model of Paclitaxel-Induced Neuropathy, file e398c381-7e98-179a-e053-3705fe0a4cff
|
100
|
|
Intestinal inflammation increases convulsant activity and reduces antiepileptic drug efficacy in a mouse model of epilepsy., file e398c37e-940c-179a-e053-3705fe0a4cff
|
98
|
|
Efficacy of isothiocyanate-based compounds on different forms of persistent pain., file e398c37e-e71d-179a-e053-3705fe0a4cff
|
97
|
|
Cannabidiol protects dopaminergic neuronal cells from cadmium, file e398c37f-481e-179a-e053-3705fe0a4cff
|
96
|
|
Protective Effects Induced by Two Polyphenolic Liquid Complexes from Olive (Olea europaea, mainly Cultivar Coratina) Pressing Juice in Rat Isolated Tissues Challenged with LPS., file e398c37e-db86-179a-e053-3705fe0a4cff
|
94
|
|
Intranasal Low-Dose Naltrexone Against Opioid Side Effects: A Preclinical Study, file e398c380-271a-179a-e053-3705fe0a4cff
|
93
|
| Totale |
29.540 |