MATERAZZI, SERENA
MATERAZZI, SERENA
Scienze della Salute (DSS)
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.
2007 Trevisani M, Siemens J, Materazzi S, Bautista DM, Nassini R, Campi B, Imamachi N, Andrè E, Patacchini R, Cottrell GS, Gatti R, Basbaum AI, Bunnett NW, Julius D, Geppetti P.
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation.
2012 Baraldi PG, Romagnoli R, Saponaro G, Aghazadeh Tabrizi M, Baraldi S, Pedretti P, Fusi C, Nassini R, Materazzi S, Geppetti P, Preti D.
A bicarbonate-alkaline mineral water protects from ethanol-induced hemorrhagic gastric lesions in mice.
2010 Nassini R, Andrè E, Gazzieri D, De Siena G, Zanasi A, Geppetti P, Materazzi S.
A role for transient receptor potential vanilloid 4 in tonicity-induced neurogenic inflammation.
2010 Vergnolle N, Cenac N, Altier C, Cellars L, Chapman K, Zamponi GW, Materazzi S, Nassini R, Liedtke W, Cattaruzza F, Grady EF, Geppetti P, Bunnett NW.
Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents.
2010 Nassini R, Materazzi S, Andrè E, Sartiani L, Aldini G, Trevisani M, Carnini C, Massi D, Pedretti P, Carini M, Cerbai E, Preti D, Villetti G, Civelli M, Trevisan G, Azzari C, Stokesberry S, Sadofsky L, McGarvey L, Patacchini R, Geppetti P.
Activation of TRPA1 on dural afferents: a potential mechanism of headache pain
2012 Edelmayer RM, Le LN, Yan J, Wei X, Nassini R, Materazzi S, Preti D, Appendino G, Geppetti P, Dodick DW, Vanderah TW, Porreca F, Dussor G.
Analysis of protease-activated receptor-1 and -2 in human scar formation.
2007 S. Materazzi; S. Pellerito; C. Di Serio; M. Paglierani; A. Naldini; C. Ardinghi; F. Carraro; P. Geppetti; G. Cirino; M. Santucci; F. Tarantini; D. Massi
Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents.
2008 Andrè E, Campi B, Materazzi S, Trevisani M, Amadesi S, Massi D, Creminon C, Vaksman N, Nassini R, Civelli M, Baraldi PG, Poole DP, Bunnett NW, Geppetti P, Patacchini R.
Cough sensors. II. Transient receptor potential membrane receptors on cough sensors
2009 Materazzi, S; Nassini, R; Gatti, R; Trevisani, M; Geppetti, P
Cough: The Emerging Role of the TRPA1 Channel.
2010 Geppetti P; Patacchini R; Nassini R; Materazzi S.
Critical role of calcitonin gene-related peptide receptors in cortical spreading depression
2012 A. Tozzi; A. de Iure; M. Di Filippo; C. Costa; S. Caproni; A. Pisani; P. Bonsi; B. Picconi; L.M. Cupini; S. Materazzi; P. Geppetti; P. Sarchielli; P. Calabresi
Detrimental and Beneficial Effects of Ethanol by Stimulation of TRPV1 in Sensory Neurons
2008 S. Materazzi; R. Nassini; S. Benemei; S. Castellani; P. Geppetti
Effects of hydrogen sulfide (H2S) on mesenteric perfusion in experimental induced intestinal ischemia in a porcine model
2015 Pavoni, V; Nicoletti, P; Benemei, S; Materazzi, S; Perna, F; Romagnoli, S; Chelazzi, C; Zagli, G; Coratti, A3.
Functional characterization of human ProNGF and NGF mutants: Identification of NGF P61SR100E as a "Painless" lead investigational candidate for therapeutic applications
2015 Malerba F, Paoletti F, Ercole BB, Materazzi S, Nassini R, Coppi E, Patacchini R, Capsoni S, Lamba D, Cattaneo A.
In Vivo models of neurogenic inflammation
2006 P.Geppetti;S.Materazzi;P.Nicoletti;M.Trevisani
Involvement of PAR-2 in vitiligo
2007 S. Moretti; G. Baroni; A. Naldini; A. Simoni; F. Prignano; T. Lotti; F. Tarantini; S. Materazzi; R. Nassini; D. Massi
Keep in Mind TRPA1 When Prescribing Metamizole!
2016 Benemei S, Nassini R, Materazzi S, Geppetti P.
LC-MS/MS method for simultaneous determination on a dried blood spot of multiple analytes relevant for treatment monitoring in patients with tyrosinemia type I
2012 la Marca G; Malvagia S; Materazzi S; Della Bona ML; Boenzi S; Martinelli D; Dionisi-Vici C.
Migraine is a high prevalence disorder which affects a significant proportion of the general population, especially women during their central and more productive time of the life, thus causing severe disability. The genetic basis of the disease is unknown and the mechanism is poorly understood. The possibility that following a perturbation in the central nervous system, and particularly in the brainstem, trigeminal neurons become hyperexcitable and produce an uncontrolled release of sensory neuropeptides which eventually results in arterial vasodilatation and neuronal sensitization, has been gaining credit from studies in experimental animals and humans. In particular, experimental and clinical data with antagonists of the calcitonin gene-related peptide (CGRP) propose this molecule and its receptor as a major target for migraine treatment.
2010 Silvia Benemei, Francesco De Cesaris, Paola Nicoletti, Serena Materazzi, Romina Nassini, Pierangelo Geppetti
Migraine Models
2009 S. Benemei; F. De Cesaris; P. Nicoletti; S. Materazzi; R. Nassini; P. Geppetti.