Nome |
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Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTPe1B: In vitro, in silico, and in vivo approaches, file e398c378-b664-179a-e053-3705fe0a4cff
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745
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Metabolic Reprogramming in Anticancer Drug Resistance: A Focus on Amino Acids, file e398c381-4431-179a-e053-3705fe0a4cff
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483
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Synthesis, in vitro and in silico screening of ethyl 2-(6-substituted benzo[d]thiazol-2-ylamino)-2-oxoacetates as protein-tyrosine phosphatase 1B inhibitors., file e398c378-ddb6-179a-e053-3705fe0a4cff
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321
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Effect of natural compounds on insulin signaling., file e398c37e-5774-179a-e053-3705fe0a4cff
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288
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Effect of IR laser on myoblasts: a proteomic study, file e398c378-e164-179a-e053-3705fe0a4cff
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276
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New 4-[(5-arylidene-2-arylimino-4-oxo-3-thiazolidinyl)methyl]benzoic acids active as protein tyrosine phosphatase inhibitors endowed with insulinomimetic effect on mouse C2C12 skeletal muscle cells, file e398c378-ddb7-179a-e053-3705fe0a4cff
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247
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Role of tyrosine phosphorylation in modulating cancer cell metabolism, file e398c37f-e7df-179a-e053-3705fe0a4cff
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227
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Lscβ and lscγ, two novel levansucrases of Pseudomonas syringae pv. actinidiae biovar 3, the causal agent of bacterial canker of kiwifruit, show
different enzymatic properties, file e398c380-e529-179a-e053-3705fe0a4cff
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214
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miR-210-3p mediates metabolic adaptation and sustains DNA damage repair of resistant colon cancer cells to treatment with 5-fluorouracil, file e398c37e-b7ce-179a-e053-3705fe0a4cff
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210
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Honey extracts inhibit PTP1B, upregulate insulin receptor expression, and enhance glucose uptake in human HepG2 cells, file e398c37e-76b1-179a-e053-3705fe0a4cff
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194
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Acylphosphatase Is a Strong Apoptosis Inducer in HeLa Cell Line, file e398c378-969c-179a-e053-3705fe0a4cff
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190
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The contribution of acidic residues to the conformational stability of common-type acylphosphatase, file e398c378-9199-179a-e053-3705fe0a4cff
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184
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Acylphosphatase possesses nucleoside triphosphatase and nucleoside diphosphatase activities, file e398c378-9667-179a-e053-3705fe0a4cff
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179
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The in vivo tyrosine phosphorylation level of yeast immunophilin Fpr3 is influenced by the LMW-PTP Ltp1., file e398c378-90f9-179a-e053-3705fe0a4cff
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175
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Porcine liver low M(r) phosphotyrosine protein phosphatase: the amino acid sequence, file e398c378-9a85-179a-e053-3705fe0a4cff
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165
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A nucleophilic catalysis step is involved in the hydrolysis of aryl phosphate monoesters by human CT acylphosphatase, file e398c378-955f-179a-e053-3705fe0a4cff
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164
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Targeting LMW-PTP to sensitize melanoma cancer cells toward chemo- and radiotherapy., file e398c37c-e98d-179a-e053-3705fe0a4cff
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163
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Highly Charged Ruthenium(II) Polypyridyl Complexes as Effective Photosensitizer in Photodynamic Therapy, file e398c37e-472f-179a-e053-3705fe0a4cff
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160
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S-Homocysteinylation effects on transthyretin: worsening of cardiomyopathy onset, file e398c37f-88db-179a-e053-3705fe0a4cff
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160
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Cloning of murine low molecular weight phosphotyrosine protein phosphatase cDNA: identification of a new isoform, file e398c378-95be-179a-e053-3705fe0a4cff
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156
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The effects of CA IX catalysis products within tumor microenvironment, file e398c378-e729-179a-e053-3705fe0a4cff
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155
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Design and evaluation of non-carboxylate 5-arylidene-2-thioxo-4-imidazolidinones as novel non-competitive inhibitors of protein tyrosine phosphatase 1B, file e398c37e-e9ae-179a-e053-3705fe0a4cff
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141
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A single amino acid mutation affects elicitor and expansins-like activities of cerato-platanin, a non-catalytic fungal protein., file e398c37b-f8ef-179a-e053-3705fe0a4cff
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137
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Catechol-Containing Hydroxylated Biomimetic 4-Thiaflavanes as Inhibitors of Amyloid Aggregation, file e398c37b-aef0-179a-e053-3705fe0a4cff
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133
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Oncogenic Tyrosine Phosphatases: Novel Therapeutic Targets for Melanoma Treatment, file e398c380-2ff4-179a-e053-3705fe0a4cff
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128
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Study on a fermented whole wheat: Phenolic content, activity on PTP1B enzyme and in vitro prebiotic properties, file e398c37e-642f-179a-e053-3705fe0a4cff
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125
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Mechanism of acylphosphatase inactivation by Woodward's reagent K, file e398c378-96cc-179a-e053-3705fe0a4cff
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112
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LMW-PTP targeting potentiates the effects of drugs used in chronic lymphocytic leukemia therapy, file e398c37e-47b0-179a-e053-3705fe0a4cff
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110
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HYDROGEN PEROXIDE TRIGGERS THE FORMATION OF A DISULFIDE DIMER OF MUSCLE ACYLPHOSPHATASE AND MODIFIES SOME FUNCTIONAL PROPERTIES OF THE ENZYME, file e398c378-8379-179a-e053-3705fe0a4cff
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106
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Does Fermentation Really Increase the Phenolic Content in Cereals? A Study on Millet, file e398c37f-21e2-179a-e053-3705fe0a4cff
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95
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Regulation of glucose metabolism by bioactive phytochemicals for the management of type 2 diabetes mellitus., file e398c381-d70f-179a-e053-3705fe0a4cff
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86
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Morin: A Promising Natural Drug, file e398c381-91f5-179a-e053-3705fe0a4cff
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76
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uPAR-expressing melanoma exosomes promote angiogenesis by VE-Cadherin, EGFR and uPAR overexpression and rise of ERK1,2 signaling in endothelial cells, file e398c380-7ab8-179a-e053-3705fe0a4cff
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70
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5-Fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like trait, file e398c379-90f4-179a-e053-3705fe0a4cff
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68
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Dietary polyphenols as antidiabetic agents: Advances and opportunities, file e398c37f-977d-179a-e053-3705fe0a4cff
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68
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Design of Biocompatible Liquid Cristal Elastomers Reproducing the Mechanical Properties of Human Cardiac Muscle, file e398c380-b1fe-179a-e053-3705fe0a4cff
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59
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Development of Light-Responsive Liquid Crystalline Elastomers to Assist Cardiac Contraction, file e398c380-a820-179a-e053-3705fe0a4cff
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53
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Activated fibroblasts enhance cancer cell migration by microvesicles-mediated transfer of Galectin-1, file e398c381-3d34-179a-e053-3705fe0a4cff
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51
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Insights into Cytotoxic Behavior of Lepadins and Structure Elucidation of the New Alkaloid Lepadin L from the Mediterranean Ascidian Clavelina lepadiformis, file e398c381-f682-179a-e053-3705fe0a4cff
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51
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Thermodynamics and kinetics of folding of common type acylphosphatase, file e398c378-8b7d-179a-e053-3705fe0a4cff
|
48
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3,4,5-Trihydroxypiperidine Based Multivalent
Glucocerebrosidase (GCase) Enhancers, file e398c382-2976-179a-e053-3705fe0a4cff
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47
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Cell instructive Liquid Crystalline Networks for myotube formation, file e398c381-5bbe-179a-e053-3705fe0a4cff
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38
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Differential impact of cold and hot tea extracts on tyrosine phosphatases regulating insulin receptor activity: a focus on PTP1B and LMW-PTP, file e398c381-ad82-179a-e053-3705fe0a4cff
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38
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Natural α-glucosidase and protein tyrosine phosphatase 1B inhibitors: A source of scaffold molecules for synthesis of new multitarget antidiabetic drugs, file e398c381-ed8b-179a-e053-3705fe0a4cff
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38
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Dihydromyricetin Attenuates Streptozotocin-induced Liver Injury and Inflammation in Rats via Regulation of NF-κB and AMPK Signaling Pathway, file e398c37f-88dd-179a-e053-3705fe0a4cff
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34
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Dual targeting of ptp1b and aldose reductase with marine drug phosphoeleganin: A promising strategy for treatment of type 2 diabetes, file e398c381-cb8a-179a-e053-3705fe0a4cff
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34
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Highly Charged Ruthenium(II) Polypyridyl Complexes as Effective Photosensitizer in Photodynamic Therapy, file e398c381-0ae1-179a-e053-3705fe0a4cff
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31
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In depth study of phenolic profile and PTP-1B inhibitory power of cold-pressed grape seed oils of different varieties, file e398c381-50b7-179a-e053-3705fe0a4cff
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31
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LMW-PTP modulates glucose metabolism in cancer cells, file e398c381-f1f6-179a-e053-3705fe0a4cff
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31
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The functionalization of nanostructured carbon materials for biological application, file e398c381-4163-179a-e053-3705fe0a4cff
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27
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New concepts about fibroblasts trophic
function, file e398c378-ea9a-179a-e053-3705fe0a4cff
|
24
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Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair, file e398c381-e756-179a-e053-3705fe0a4cff
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21
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Human Acid β-Glucosidase Inhibition by Carbohydrate Derived Iminosugars: Towards New Pharmacological Chaperones for Gaucher Disease, file e398c381-0492-179a-e053-3705fe0a4cff
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20
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A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity, file e398c382-4ec3-179a-e053-3705fe0a4cff
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18
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In search for multi-target ligands as potential agents for diabetes mellitus and its complications—a structure-activity relationship study on inhibitors of aldose reductase and protein tyrosine phosphatase 1b, file 507c45cd-3d37-473f-b2fb-6bb5d2b68f37
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12
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Dual targeting of PTP1B and glucosidases with new bifunctional iminosugar inhibitors to address type 2 diabetes, file e398c380-b8c3-179a-e053-3705fe0a4cff
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12
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SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis, file b72fa9dd-d341-401c-8177-d07abf4be89e
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10
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Identifying Human PTP1B Enzyme Inhibitors from Marine Natural Products: Perspectives for Developing of Novel Insulin-Mimetic Drugs, file e398c382-4ec0-179a-e053-3705fe0a4cff
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9
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LMW-PTP modulates glucose metabolism in cancer cells, file e398c37d-87c8-179a-e053-3705fe0a4cff
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7
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Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair, file e398c37e-8882-179a-e053-3705fe0a4cff
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7
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Enzymatic inhibitors from natural sources: A huge collection of new potential drugs, file f868290a-46c2-44cb-8c0e-9042fad8c715
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7
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Synthesis of a New beta-Galactosidase Inhibitor Displaying
Pharmacological Chaperone Properties for GM1 Gangliosidosis, file f9afec13-bd83-4006-bc06-d650cee0db0a
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7
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Human Acid β-Glucosidase Inhibition by Carbohydrate Derived Iminosugars: Towards New Pharmacological Chaperones for Gaucher Disease, file e398c379-9710-179a-e053-3705fe0a4cff
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6
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In depth study of phenolic profile and PTP-1B inhibitory power of cold-pressed grape seed oils of different varieties, file e398c37d-82a0-179a-e053-3705fe0a4cff
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6
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Cancer associated fibroblasts transfer lipids and proteins to cancer cells through cargo vesicles supporting tumor growth, file e398c379-79a4-179a-e053-3705fe0a4cff
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3
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Evidence for a multivalent effect in inhibition of sulfatases involved in lysosomal storage disorders (LSDs), file e398c37a-7dc7-179a-e053-3705fe0a4cff
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3
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Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair, file e398c37c-4ac1-179a-e053-3705fe0a4cff
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3
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Photoswitchable inhibitors of human β-glucocerebrosidase, file e398c381-cfc2-179a-e053-3705fe0a4cff
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3
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Light-Triggered Control of Glucocerebrosidase Inhibitors: Towards Photoswitchable Pharmacological Chaperones, file f50eec27-7ab1-448b-9e9d-9c6a71f2e727
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3
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Ruthenium(II) polypyridyl complexes as versatile tools in the design of photoresponsive compounds for biological applications, file 17afa0e0-a2a7-4f8b-b2ee-9f8b7e8bf424
|
2
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The ”click-on-tube” approach for the production of efficient drug carriers based on oxidize multiwalled carbon nanotubes, file e398c37a-b21c-179a-e053-3705fe0a4cff
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2
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Multiwalled carbon nanotubes for drug delivery: Efficiency related to length and incubation time, file e398c37b-aec4-179a-e053-3705fe0a4cff
|
2
|
Morin-dependent inhibition of low molecular weight protein
tyrosine phosphatase (LMW-PTP) restores sensitivity to
apoptosis during colon carcinogenesis: Studies in vitro and in
vivo, in an Apc-driven model of colon cancer, file e398c37d-f70e-179a-e053-3705fe0a4cff
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2
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Dual targeting of PTP1B and glucosidases with new bifunctional iminosugar inhibitors to address type 2 diabetes, file e398c37e-232d-179a-e053-3705fe0a4cff
|
2
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Evidence of Insulin-Sensitizing and Mimetic Activity of the Sesquiterpene Quinone Avarone, a Protein Tyrosine Phosphatase 1B and Aldose Reductase Dual Targeting Agent from the Marine Sponge Dysidea avara, file 90ee2a01-f212-4185-b834-e410252f4eb1
|
1
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Studying the trafficking of labeled trodusquemine and its application as nerve marker for light-sheet and expansion microscopy, file a435e799-e1cd-4c9d-a713-bf416b0f6eae
|
1
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Azido-Substituted BODIPY Dyes for the Production of Fluorescent Carbon Nanotubes, file e398c379-90f7-179a-e053-3705fe0a4cff
|
1
|
Low molecular weight protein tyrosine phosphatase: Multifaceted functions of an evolutionarily conserved enzyme, file e398c37a-9c8a-179a-e053-3705fe0a4cff
|
1
|
Morin: A Promising Natural Drug, file e398c37b-0b96-179a-e053-3705fe0a4cff
|
1
|
Effect of selected strains of lactobacilli on the antioxidant and anti-inflammatory properties of sourdough, file e398c37d-b699-179a-e053-3705fe0a4cff
|
1
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Metformin salts with oxidized multiwalled carbon nanotubes: In vitro biological activity and inhibition of CNT internalization, file e398c37d-d33a-179a-e053-3705fe0a4cff
|
1
|
Multiwalled carbon nanotubes for combination therapy: a biodistribution and efficacy pilot study, file e398c37e-204c-179a-e053-3705fe0a4cff
|
1
|
Regulation of glucose metabolism by bioactive phytochemicals for the management of type 2 diabetes mellitus., file e398c37e-37cc-179a-e053-3705fe0a4cff
|
1
|
Totale |
7.322 |