PAOLI, PAOLO
 Distribuzione geografica
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Continente #
EU - Europa 6.000
NA - Nord America 5.563
AS - Asia 967
AF - Africa 34
SA - Sud America 5
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 12.572
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Nazione #
US - Stati Uniti d'America 5.547
PL - Polonia 2.916
RU - Federazione Russa 1.045
IT - Italia 724
IE - Irlanda 505
SE - Svezia 347
HK - Hong Kong 250
SG - Singapore 203
CN - Cina 201
IN - India 113
DE - Germania 109
UA - Ucraina 96
FI - Finlandia 79
JO - Giordania 74
VN - Vietnam 64
GB - Regno Unito 61
CH - Svizzera 53
CI - Costa d'Avorio 26
TH - Thailandia 24
FR - Francia 20
ES - Italia 19
CA - Canada 15
TR - Turchia 14
KR - Corea 11
JP - Giappone 7
BE - Belgio 6
NL - Olanda 6
SC - Seychelles 5
GR - Grecia 3
RO - Romania 3
AU - Australia 2
BR - Brasile 2
CO - Colombia 2
CZ - Repubblica Ceca 2
TW - Taiwan 2
AE - Emirati Arabi Uniti 1
AM - Armenia 1
BG - Bulgaria 1
DK - Danimarca 1
DZ - Algeria 1
EU - Europa 1
HR - Croazia 1
KH - Cambogia 1
LI - Liechtenstein 1
LT - Lituania 1
MX - Messico 1
PE - Perù 1
PK - Pakistan 1
RS - Serbia 1
TN - Tunisia 1
UG - Uganda 1
Totale 12.572
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Città #
Warsaw 2.914
Fairfield 933
Ashburn 538
Dublin 484
Chandler 479
Woodbridge 415
Cambridge 368
Seattle 340
Wilmington 322
Houston 315
Florence 274
Hong Kong 165
Singapore 160
Altamura 153
Jacksonville 145
Lawrence 142
Princeton 126
Ann Arbor 114
Mumbai 93
Beijing 80
Buffalo 79
Boardman 68
Boston 68
Medford 63
San Diego 58
Shanghai 56
Dong Ket 54
Bern 50
Moscow 45
New York 42
Santa Clara 33
Abidjan 26
Ron Phibun 24
Norwalk 23
Phoenix 23
Kent 19
Washington 19
Hillsboro 18
Los Angeles 17
Menlo Park 17
Milan 16
Barcelona 14
London 14
West Jordan 14
Bremen 13
Falls Church 13
Pune 13
Izmir 12
Andover 11
Redwood City 11
Redmond 10
Saronno 10
Helsinki 9
Prato 9
Dearborn 8
Rome 8
Toronto 8
Bari 7
Brussels 6
Cagliari 6
Detroit 6
Lappeenranta 6
Naples 6
Paris 6
Tappahannock 6
Auburn Hills 5
Laurel 5
Lucca 5
Munich 5
Nanjing 5
Seoul 5
Tokyo 5
Troy 5
Montréal 4
Romola 4
Siena 4
Verona 4
Albignasego 3
Amsterdam 3
Bagno A Ripoli 3
Civitella in Val di Chiana 3
Cleveland 3
Esslingen am Neckar 3
Frankfurt Am Main 3
Mascalucia 3
Modena 3
Napoli 3
Pisa 3
Renton 3
San Mateo 3
Vinci 3
Wuhan 3
Anguillara Sabazia 2
Arezzo 2
Balashikha 2
Bogotá 2
Cardito 2
Carpeneto 2
Castelliri 2
Cavriglia 2
Totale 9.721
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Nome #
Effect of IR laser on myoblasts: a proteomic study 275
Acylphosphatase Is a Strong Apoptosis Inducer in HeLa Cell Line 258
A nucleophilic catalysis step is involved in the hydrolysis of aryl phosphate monoesters by human CT acylphosphatase 250
Acylphosphatase possesses nucleoside triphosphatase and nucleoside diphosphatase activities 245
HYDROGEN PEROXIDE TRIGGERS THE FORMATION OF A DISULFIDE DIMER OF MUSCLE ACYLPHOSPHATASE AND MODIFIES SOME FUNCTIONAL PROPERTIES OF THE ENZYME 244
The in vivo tyrosine phosphorylation level of yeast immunophilin Fpr3 is influenced by the LMW-PTP Ltp1. 243
A single amino acid mutation affects elicitor and expansins-like activities of cerato-platanin, a non-catalytic fungal protein. 243
Cloning of murine low molecular weight phosphotyrosine protein phosphatase cDNA: identification of a new isoform 242
Catechol-Containing Hydroxylated Biomimetic 4-Thiaflavanes as Inhibitors of Amyloid Aggregation 240
The effects of CA IX catalysis products within tumor microenvironment 229
Porcine liver low M(r) phosphotyrosine protein phosphatase: the amino acid sequence 225
Mechanism of acylphosphatase inactivation by Woodward's reagent K 224
The contribution of acidic residues to the conformational stability of common-type acylphosphatase 210
Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTPe1B: In vitro, in silico, and in vivo approaches 207
New 4-[(5-arylidene-2-arylimino-4-oxo-3-thiazolidinyl)methyl]benzoic acids active as protein tyrosine phosphatase inhibitors endowed with insulinomimetic effect on mouse C2C12 skeletal muscle cells 204
Synthesis, in vitro and in silico screening of ethyl 2-(6-substituted benzo[d]thiazol-2-ylamino)-2-oxoacetates as protein-tyrosine phosphatase 1B inhibitors. 196
Thermodynamics and kinetics of folding of common type acylphosphatase 191
New concepts about fibroblasts trophic function 188
Targeting LMW-PTP to sensitize melanoma cancer cells toward chemo- and radiotherapy. 186
Highly Charged Ruthenium(II) Polypyridyl Complexes as Effective Photosensitizer in Photodynamic Therapy 176
Honey extracts inhibit PTP1B, upregulate insulin receptor expression, and enhance glucose uptake in human HepG2 cells 161
LMW-PTP targeting potentiates the effects of drugs used in chronic lymphocytic leukemia therapy 161
Effect of natural compounds on insulin signaling. 154
Study on a fermented whole wheat: Phenolic content, activity on PTP1B enzyme and in vitro prebiotic properties 150
Development of Light-Responsive Liquid Crystalline Elastomers to Assist Cardiac Contraction 149
miR-210-3p mediates metabolic adaptation and sustains DNA damage repair of resistant colon cancer cells to treatment with 5-fluorouracil 143
5-Fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like trait 140
Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair 130
Low molecular weight protein tyrosine phosphatase: Multifaceted functions of an evolutionarily conserved enzyme 126
In depth study of phenolic profile and PTP-1B inhibitory power of cold-pressed grape seed oils of different varieties 126
Cell instructive Liquid Crystalline Networks for myotube formation 126
LMW-PTP modulates glucose metabolism in cancer cells 125
Liquid Crystal-Induced Myoblast Alignment 125
S-Homocysteinylation effects on transthyretin: worsening of cardiomyopathy onset 117
2-Methoxybenzoyl phosphate: a new substrate for continuous fluorimetric and spectrophotometric acyl phosphatase assays 115
Human Acid β-Glucosidase Inhibition by Carbohydrate Derived Iminosugars: Towards New Pharmacological Chaperones for Gaucher Disease 115
The functionalization of nanostructured carbon materials for biological application 114
Azido-Substituted BODIPY Dyes for the Production of Fluorescent Carbon Nanotubes 113
Design and evaluation of non-carboxylate 5-arylidene-2-thioxo-4-imidazolidinones as novel non-competitive inhibitors of protein tyrosine phosphatase 1B 113
The insulin-mimetic effect of Morin: A promising molecule in diabetes treatment 112
Anoikis molecular pathways and its role in cancer progression. 112
Multiwalled carbon nanotubes for drug delivery: Efficiency related to length and incubation time 112
The ”click-on-tube” approach for the production of efficient drug carriers based on oxidize multiwalled carbon nanotubes 110
Evidence for a multivalent effect in inhibition of sulfatases involved in lysosomal storage disorders (LSDs) 109
Effect of selected strains of lactobacilli on the antioxidant and anti-inflammatory properties of sourdough 109
Does Fermentation Really Increase the Phenolic Content in Cereals? A Study on Millet 109
Cancer associated fibroblasts transfer lipids and proteins to cancer cells through cargo vesicles supporting tumor growth 108
Multiwalled carbon nanotubes for combination therapy: a biodistribution and efficacy pilot study 108
Dual targeting of PTP1B and glucosidases with new bifunctional iminosugar inhibitors to address type 2 diabetes 107
Morin: A Promising Natural Drug 105
Low Molecular Weight-Protein Tyrosine Phosphatase and Caveolin-1: Interaction and Isoenzyme-Dependent Regulation 105
INSULIN INHIBITS PLATELET-DERIVED GROWTH FACTOR-INDUCED CELL PROLIFERATION 105
SITE-DIRECTED MUTAGENESIS OF TWO AROMATIC RESIDUES LINING THE ACTIVE SITE POCKET OF THE YEAST LTP1 104
An investigation on 4-thiazolidinone derivatives as dual inhibitors of aldose reductase and protein tyrosine phosphatase 1B, in the search for potential agents for the treatment of type 2 diabetes mellitus and its complications 103
Common-type acylphosphatase: steady-state kinetics and leaving-group dependence. 102
Discovery of 4-[(5-arylidene-4-oxothiazolidin-3-yl)methyl]benzoic acid derivatives active as novel potent allosteric inhibitors of protein tyrosine phosphatase 1B: In silico studies and in vitro evaluation as insulinomimetic and anti-inflammatory agents 99
Metformin salts with oxidized multiwalled carbon nanotubes: In vitro biological activity and inhibition of CNT internalization 98
Protein N-homocysteinylation induces the formation of toxic amyloid-like protofibrils 96
Synthesis, biological activity and structure activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells 95
5-Arylidene-2phenylimino-4-thiazolidinones as PTP1B and LMW-PTP inhibitors 91
Design of Biocompatible Liquid Cristal Elastomers Reproducing the Mechanical Properties of Human Cardiac Muscle 91
Protective effect of new S-acylglutathione derivatives against amyloid induced oxidative stress 90
Antioxidant and anti-inflammatory properties of sourdoughs containing selected Lactobacilli strains are retained in breads 89
Regulation of glucose metabolism by bioactive phytochemicals for the management of type 2 diabetes mellitus. 89
Stereoselective Synthesis of C‑2 Alkylated Trihydroxypiperidines: Novel Pharmacological Chaperones for Gaucher Disease 86
Structure-Based Optimization of Benzoic Acids as Inhibitors of Protein Tyrosine Phosphatase 1B and Low Molecular Weight Protein Tyrosine Phosphatase 85
Morin-dependent inhibition of low molecular weight protein tyrosine phosphatase (LMW-PTP) restores sensitivity to apoptosis during colon carcinogenesis: Studies in vitro and in vivo, in an Apc-driven model of colon cancer 85
Design, synthesis, in vitro, in vivo and in silico pharmacological characterization of antidiabetic N-Boc-L-tyrosine-based compounds 81
PrPc activation induces neurite outgrowth and differentiation in PC12 cells: role for caveolin-1 in the signal transduction pathway 80
Synthesis, activity and molecular modeling of a new series of chromones as low molecular weight protein tyrosine phosphatase inhibitors 80
uPAR-expressing melanoma exosomes promote angiogenesis by VE-Cadherin, EGFR and uPAR overexpression and rise of ERK1,2 signaling in endothelial cells 80
3,4,5-Trihydroxypiperidine Based Multivalent Glucocerebrosidase (GCase) Enhancers 80
Oncogenic Tyrosine Phosphatases: Novel Therapeutic Targets for Melanoma Treatment 79
Synthesis, in vitro and computational studies of protein tyrosine phosphatase 1B inhibition of a small library of 2-arylsulfonylaminobenzothiazoles with antihyperglycemic activity 78
Glucocerebrosidase (GCase) activity modulation by 2-alkyl trihydroxypiperidines: Inhibition and pharmacological chaperoning 78
Lscβ and lscγ, two novel levansucrases of Pseudomonas syringae pv. actinidiae biovar 3, the causal agent of bacterial canker of kiwifruit, show different enzymatic properties 76
Synthesis and evaluation of thiazolidine-2,4-dione/benzazole derivatives as inhibitors of protein tyrosine phosphatase 1B (PTP-1B): Antihyperglycemic activity with molecular docking study 75
Bioactive Properties of Breads Made with Sourdough of Hull-Less Barley or Conventional and Pigmented Wheat Flours 75
Tumor microenvironment and metabolism in prostate cancer. 72
Dietary polyphenols as antidiabetic agents: Advances and opportunities 68
Photoswitchable inhibitors of human β-glucocerebrosidase 64
5-Arylidene- 2,4-Thiazolidinediones Inhibitors of Protein Tyrosine Phosphatases 63
Insulin inhibits platelet-derived growth factor-induced cell proliferation 63
Caveolin-1 inhibits LMW-PTP isoenzymes catalytic activity 62
In vitro and in silico PTP-1B inhibition and in vivo antidiabetic activity of semisynthetic moronic acid derivatives 62
Identifying Human PTP1B Enzyme Inhibitors from Marine Natural Products: Perspectives for Developing of Novel Insulin-Mimetic Drugs 58
Activated fibroblasts enhance cancer cell migration by microvesicles-mediated transfer of Galectin-1 57
Role of tyrosine phosphorylation in modulating cancer cell metabolism 56
A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity 56
Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition 53
Studying the trafficking of labeled trodusquemine and its application as nerve marker for light-sheet and expansion microscopy 52
SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis 52
Fibroblasts transfer lipids and proteins to tumor cells through cargo vescicles supporting their growth 52
Identification of RPTPalpha as responsible for Fyn activation in PrPc signalling 51
Structure-activity relationships in a series of auranofin analogues showing remarkable antiproliferative properties 50
Metabolic Reprogramming in Anticancer Drug Resistance: A Focus on Amino Acids 49
Ruthenium(II) polypyridyl complexes as versatile tools in the design of photoresponsive compounds for biological applications 48
Signal transduction pathway in PrPc-dependent neuritogenesis 47
Novel benzoic acids as inhibitors of PTP1B and LMW-PTP, molecular targets to fight diabetes and obesity 46
Lscβ and lscγ, two novel levansucrases of Pseudomonas syringae pv. actinidiae biovar 3, the causal agent of bacterial canker of kiwifruit, show different enzymatic properties 46
Totale 11.882
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Categoria #
all - tutte 36.077
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 36.077
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.168 0 0 0 199 333 285 271 329 263 185 263 40
2020/20211.817 145 164 87 203 87 170 91 144 191 317 92 126
2021/2022960 37 83 63 66 31 69 42 57 40 61 191 220
2022/20232.274 219 419 108 153 161 369 304 153 230 14 68 76
2023/20241.102 24 98 142 59 99 190 81 243 9 61 60 36
2024/20251.523 175 623 371 354 0 0 0 0 0 0 0 0
Totale 12.793