PAOLI, PAOLO
 Distribuzione geografica
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Continente #
NA - Nord America 11.283
EU - Europa 8.819
AS - Asia 4.693
SA - Sud America 600
Continente sconosciuto - Info sul continente non disponibili 286
AF - Africa 148
OC - Oceania 76
Totale 25.905
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Nazione #
US - Stati Uniti d'America 11.063
PL - Polonia 2.940
RU - Federazione Russa 2.233
IT - Italia 1.665
SG - Singapore 1.336
CN - Cina 1.145
HK - Hong Kong 611
IE - Irlanda 505
VN - Vietnam 503
BR - Brasile 483
KR - Corea 375
SE - Svezia 365
DE - Germania 231
FR - Francia 226
FI - Finlandia 218
IN - India 182
CA - Canada 146
GB - Regno Unito 131
BD - Bangladesh 126
UA - Ucraina 106
ID - Indonesia 91
JO - Giordania 81
AU - Australia 74
JP - Giappone 58
CH - Svizzera 55
AR - Argentina 53
ES - Italia 42
NL - Olanda 40
MX - Messico 34
CI - Costa d'Avorio 29
TH - Thailandia 28
TR - Turchia 28
ZA - Sudafrica 28
CO - Colombia 20
IQ - Iraq 20
PK - Pakistan 17
NG - Nigeria 15
UZ - Uzbekistan 15
MA - Marocco 13
NP - Nepal 12
PE - Perù 12
BE - Belgio 11
BJ - Benin 11
SA - Arabia Saudita 10
AE - Emirati Arabi Uniti 9
DZ - Algeria 9
KE - Kenya 9
CL - Cile 8
VE - Venezuela 8
EC - Ecuador 7
LT - Lituania 7
PH - Filippine 7
AZ - Azerbaigian 6
CR - Costa Rica 6
CZ - Repubblica Ceca 6
HN - Honduras 6
JM - Giamaica 6
KZ - Kazakistan 6
MY - Malesia 6
RO - Romania 6
SC - Seychelles 6
DK - Danimarca 5
DO - Repubblica Dominicana 5
EG - Egitto 5
ET - Etiopia 5
IL - Israele 5
UY - Uruguay 5
AT - Austria 4
GR - Grecia 4
GT - Guatemala 4
PR - Porto Rico 4
PY - Paraguay 4
AL - Albania 3
BG - Bulgaria 3
GE - Georgia 3
LY - Libia 3
NI - Nicaragua 3
PA - Panama 3
RS - Serbia 3
TN - Tunisia 3
AM - Armenia 2
HR - Croazia 2
ML - Mali 2
SN - Senegal 2
AI - Anguilla 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
CU - Cuba 1
EU - Europa 1
GA - Gabon 1
GP - Guadalupe 1
IR - Iran 1
IS - Islanda 1
KH - Cambogia 1
KI - Kiribati 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
LI - Liechtenstein 1
LK - Sri Lanka 1
Totale 25.603
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Città #
Warsaw 2.934
Santa Clara 2.000
Ashburn 1.548
Singapore 973
Fairfield 932
Hong Kong 514
Dublin 482
Chandler 476
Woodbridge 415
San Jose 402
Seoul 369
Cambridge 368
Florence 361
Seattle 347
Houston 326
Wilmington 322
Council Bluffs 296
Milan 249
Beijing 229
Hefei 227
The Dalles 159
Los Angeles 157
Altamura 154
Buffalo 152
Ho Chi Minh City 150
Jacksonville 149
Lawrence 142
Princeton 125
Lauterbourg 124
Rome 118
Ann Arbor 114
Dallas 105
New York 105
Moscow 103
Hanoi 101
Helsinki 100
Mumbai 99
Boston 81
Boardman 77
Munich 75
Jakarta 72
Shanghai 68
Medford 64
Paris 63
San Diego 62
Melbourne 61
Dong Ket 52
Tokyo 52
Bern 50
Naples 44
São Paulo 40
Chicago 38
Kent 38
Clifton 36
Orem 34
Phoenix 34
London 32
Abidjan 29
Lappeenranta 29
Frankfurt am Main 27
Montreal 25
Toronto 25
Palermo 24
Ron Phibun 24
Turku 24
Haiphong 23
Norwalk 23
Turin 21
Washington 21
Chennai 19
Da Nang 19
Redondo Beach 19
Hillsboro 18
Atlanta 17
Menlo Park 17
Bari 16
Denver 16
Guangzhou 16
West Jordan 16
Abuja 15
Barcelona 15
Bologna 15
Johannesburg 15
Pune 15
Columbus 14
Figino 14
Miano 14
Stockholm 14
Tashkent 14
Amsterdam 13
Bengaluru 13
Bremen 13
Falls Church 13
Genoa 13
Rio de Janeiro 13
Brescia 12
Izmir 12
Andover 11
Brooklyn 11
Campinas 11
Totale 17.748
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Nome #
The in vivo tyrosine phosphorylation level of yeast immunophilin Fpr3 is influenced by the LMW-PTP Ltp1. 490
Effect of IR laser on myoblasts: a proteomic study 398
A nucleophilic catalysis step is involved in the hydrolysis of aryl phosphate monoesters by human CT acylphosphatase 373
Acylphosphatase possesses nucleoside triphosphatase and nucleoside diphosphatase activities 357
A single amino acid mutation affects elicitor and expansins-like activities of cerato-platanin, a non-catalytic fungal protein. 356
Acylphosphatase Is a Strong Apoptosis Inducer in HeLa Cell Line 353
Cloning of murine low molecular weight phosphotyrosine protein phosphatase cDNA: identification of a new isoform 347
Catechol-Containing Hydroxylated Biomimetic 4-Thiaflavanes as Inhibitors of Amyloid Aggregation 339
Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTPe1B: In vitro, in silico, and in vivo approaches 323
HYDROGEN PEROXIDE TRIGGERS THE FORMATION OF A DISULFIDE DIMER OF MUSCLE ACYLPHOSPHATASE AND MODIFIES SOME FUNCTIONAL PROPERTIES OF THE ENZYME 311
The effects of CA IX catalysis products within tumor microenvironment 298
New 4-[(5-arylidene-2-arylimino-4-oxo-3-thiazolidinyl)methyl]benzoic acids active as protein tyrosine phosphatase inhibitors endowed with insulinomimetic effect on mouse C2C12 skeletal muscle cells 292
New concepts about fibroblasts trophic function 290
Mechanism of acylphosphatase inactivation by Woodward's reagent K 284
Porcine liver low M(r) phosphotyrosine protein phosphatase: the amino acid sequence 282
Highly Charged Ruthenium(II) Polypyridyl Complexes as Effective Photosensitizer in Photodynamic Therapy 278
Cell instructive Liquid Crystalline Networks for myotube formation 268
Human Acid β-Glucosidase Inhibition by Carbohydrate Derived Iminosugars: Towards New Pharmacological Chaperones for Gaucher Disease 266
Dual targeting of PTP1B and glucosidases with new bifunctional iminosugar inhibitors to address type 2 diabetes 266
The contribution of acidic residues to the conformational stability of common-type acylphosphatase 262
Targeting LMW-PTP to sensitize melanoma cancer cells toward chemo- and radiotherapy. 260
Thermodynamics and kinetics of folding of common type acylphosphatase 259
Effect of natural compounds on insulin signaling. 258
Synthesis, in vitro and in silico screening of ethyl 2-(6-substituted benzo[d]thiazol-2-ylamino)-2-oxoacetates as protein-tyrosine phosphatase 1B inhibitors. 257
Honey extracts inhibit PTP1B, upregulate insulin receptor expression, and enhance glucose uptake in human HepG2 cells 256
LMW-PTP targeting potentiates the effects of drugs used in chronic lymphocytic leukemia therapy 256
5-Fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like trait 252
miR-210-3p mediates metabolic adaptation and sustains DNA damage repair of resistant colon cancer cells to treatment with 5-fluorouracil 250
Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair 246
S-Homocysteinylation effects on transthyretin: worsening of cardiomyopathy onset 245
2-Methoxybenzoyl phosphate: a new substrate for continuous fluorimetric and spectrophotometric acyl phosphatase assays 242
Development of Light-Responsive Liquid Crystalline Elastomers to Assist Cardiac Contraction 236
Morin: A Promising Natural Drug 232
Study on a fermented whole wheat: Phenolic content, activity on PTP1B enzyme and in vitro prebiotic properties 220
Low molecular weight protein tyrosine phosphatase: Multifaceted functions of an evolutionarily conserved enzyme 218
Liquid Crystal-Induced Myoblast Alignment 217
Multiwalled carbon nanotubes for drug delivery: Efficiency related to length and incubation time 216
Azido-Substituted BODIPY Dyes for the Production of Fluorescent Carbon Nanotubes 215
Anoikis molecular pathways and its role in cancer progression. 214
The ”click-on-tube” approach for the production of efficient drug carriers based on oxidize multiwalled carbon nanotubes 214
LMW-PTP modulates glucose metabolism in cancer cells 207
3,4,5-Trihydroxypiperidine Based Multivalent Glucocerebrosidase (GCase) Enhancers 207
In depth study of phenolic profile and PTP-1B inhibitory power of cold-pressed grape seed oils of different varieties 206
Multiwalled carbon nanotubes for combination therapy: a biodistribution and efficacy pilot study 206
Antioxidant and anti-inflammatory properties of sourdoughs containing selected Lactobacilli strains are retained in breads 205
Design and evaluation of non-carboxylate 5-arylidene-2-thioxo-4-imidazolidinones as novel non-competitive inhibitors of protein tyrosine phosphatase 1B 205
Does Fermentation Really Increase the Phenolic Content in Cereals? A Study on Millet 205
Effect of selected strains of lactobacilli on the antioxidant and anti-inflammatory properties of sourdough 203
Evidence for a multivalent effect in inhibition of sulfatases involved in lysosomal storage disorders (LSDs) 202
Cancer associated fibroblasts transfer lipids and proteins to cancer cells through cargo vesicles supporting tumor growth 201
Ruthenium(II) polypyridyl complexes as versatile tools in the design of photoresponsive compounds for biological applications 200
Metformin salts with oxidized multiwalled carbon nanotubes: In vitro biological activity and inhibition of CNT internalization 199
Gold nanoparticles decorated with monosaccharides and sulfated ligands as potential modulators of the lysosomal enzyme N-acetylgalactosamine-6-sulfatase (GALNS) 196
SITE-DIRECTED MUTAGENESIS OF TWO AROMATIC RESIDUES LINING THE ACTIVE SITE POCKET OF THE YEAST LTP1 195
The insulin-mimetic effect of Morin: A promising molecule in diabetes treatment 195
Studying the trafficking of labeled trodusquemine and its application as nerve marker for light-sheet and expansion microscopy 193
SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis 193
Morin-dependent inhibition of low molecular weight protein tyrosine phosphatase (LMW-PTP) restores sensitivity to apoptosis during colon carcinogenesis: Studies in vitro and in vivo, in an Apc-driven model of colon cancer 192
INSULIN INHIBITS PLATELET-DERIVED GROWTH FACTOR-INDUCED CELL PROLIFERATION 191
5-Arylidene-2phenylimino-4-thiazolidinones as PTP1B and LMW-PTP inhibitors 191
Glucocerebrosidase (GCase) activity modulation by 2-alkyl trihydroxypiperidines: Inhibition and pharmacological chaperoning 191
An investigation on 4-thiazolidinone derivatives as dual inhibitors of aldose reductase and protein tyrosine phosphatase 1B, in the search for potential agents for the treatment of type 2 diabetes mellitus and its complications 189
Metabolic Reprogramming in Anticancer Drug Resistance: A Focus on Amino Acids 188
Design of Biocompatible Liquid Cristal Elastomers Reproducing the Mechanical Properties of Human Cardiac Muscle 187
Identifying Human PTP1B Enzyme Inhibitors from Marine Natural Products: Perspectives for Developing of Novel Insulin-Mimetic Drugs 187
In search for multi-target ligands as potential agents for diabetes mellitus and its complications—a structure-activity relationship study on inhibitors of aldose reductase and protein tyrosine phosphatase 1b 186
Common-type acylphosphatase: steady-state kinetics and leaving-group dependence. 184
Low Molecular Weight-Protein Tyrosine Phosphatase and Caveolin-1: Interaction and Isoenzyme-Dependent Regulation 181
Limiting serine availability during tumor progression promotes muscle wasting in cancer cachexia 179
Targeting of tumor cells by custom antigen transfer: a novel approach for immunotherapy of cancer 179
Activated fibroblasts enhance cancer cell migration by microvesicles-mediated transfer of Galectin-1 176
Light-Triggered Control of Glucocerebrosidase Inhibitors: Towards Photoswitchable Pharmacological Chaperones 175
Protective effect of new S-acylglutathione derivatives against amyloid induced oxidative stress 175
uPAR-expressing melanoma exosomes promote angiogenesis by VE-Cadherin, EGFR and uPAR overexpression and rise of ERK1,2 signaling in endothelial cells 173
Regulation of glucose metabolism by bioactive phytochemicals for the management of type 2 diabetes mellitus. 170
Stereoselective Synthesis of C‑2 Alkylated Trihydroxypiperidines: Novel Pharmacological Chaperones for Gaucher Disease 169
pH-Responsive Trihydroxylated Piperidines Rescue The Glucocerebrosidase Activity in Human Fibroblasts Bearing The Neuronopathic Gaucher-Related L444P/L444P Mutations in GBA1 Gene 167
Bioactive Properties of Breads Made with Sourdough of Hull-Less Barley or Conventional and Pigmented Wheat Flours 167
Evidence of Insulin-Sensitizing and Mimetic Activity of the Sesquiterpene Quinone Avarone, a Protein Tyrosine Phosphatase 1B and Aldose Reductase Dual Targeting Agent from the Marine Sponge Dysidea avara 164
Oncogenic Tyrosine Phosphatases: Novel Therapeutic Targets for Melanoma Treatment 163
Design, synthesis, in vitro, in vivo and in silico pharmacological characterization of antidiabetic N-Boc-L-tyrosine-based compounds 162
A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity 161
Effect of Bovine Milk Peptides on Cell Inflammation, Proliferation and Differentiation: Milk Potential Benefits Are Preserved in an Unconventional Cow Feeding Strategy 159
Protein N-homocysteinylation induces the formation of toxic amyloid-like protofibrils 157
Lscβ and lscγ, two novel levansucrases of Pseudomonas syringae pv. actinidiae biovar 3, the causal agent of bacterial canker of kiwifruit, show different enzymatic properties 156
PrPc activation induces neurite outgrowth and differentiation in PC12 cells: role for caveolin-1 in the signal transduction pathway 155
Synthesis and evaluation of thiazolidine-2,4-dione/benzazole derivatives as inhibitors of protein tyrosine phosphatase 1B (PTP-1B): Antihyperglycemic activity with molecular docking study 155
Role of tyrosine phosphorylation in modulating cancer cell metabolism 155
Synthesis, biological activity and structure activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells 155
Insights into Cytotoxic Behavior of Lepadins and Structure Elucidation of the New Alkaloid Lepadin L from the Mediterranean Ascidian Clavelina lepadiformis 154
Photoswitchable inhibitors of human β-glucocerebrosidase 151
Synthesis of a New beta-Galactosidase Inhibitor Displaying Pharmacological Chaperone Properties for GM1 Gangliosidosis 150
5-Arylidene- 2,4-Thiazolidinediones Inhibitors of Protein Tyrosine Phosphatases 148
Designed multiple ligands for the treatment of type 2 diabetes mellitus and its complications: Discovery of (5-arylidene-4-oxo-2-thioxothiazolidin-3-yl)alkanoic acids active as novel dual-targeted PTP1B/AKR1B1 inhibitors 143
Iminosugar-Dihydroazulenes as Mutant L444P Glucocerebrosidase Enhancers 142
Discovery of 4-[(5-arylidene-4-oxothiazolidin-3-yl)methyl]benzoic acid derivatives active as novel potent allosteric inhibitors of protein tyrosine phosphatase 1B: In silico studies and in vitro evaluation as insulinomimetic and anti-inflammatory agents 141
Differential impact of cold and hot tea extracts on tyrosine phosphatases regulating insulin receptor activity: a focus on PTP1B and LMW-PTP 140
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition 139
Fibroblasts transfer lipids and proteins to tumor cells through cargo vescicles supporting their growth 138
Tyrosine is involved in yhe monomer-monomer contact in dimeric MT-acylphosphatase 135
Totale 21.734
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Categoria #
all - tutte 69.308
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 69.308
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022907 0 82 61 63 30 69 40 56 40 60 189 217
2022/20232.250 216 419 107 149 160 363 302 152 226 14 66 76
2023/20241.083 23 98 141 53 96 188 79 243 10 58 58 36
2024/20256.022 169 613 371 989 1.669 811 108 336 291 163 242 260
2025/20268.252 857 994 661 647 816 306 935 412 600 571 461 992
2026/2027431 272 159 0 0 0 0 0 0 0 0 0 0
Totale 25.905