PAOLI, PAOLO
 Distribuzione geografica
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Continente #
NA - Nord America 7.182
EU - Europa 6.620
AS - Asia 1.081
AF - Africa 34
SA - Sud America 5
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 14.925
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Nazione #
US - Stati Uniti d'America 7.165
PL - Polonia 2.916
RU - Federazione Russa 1.628
IT - Italia 736
IE - Irlanda 505
SE - Svezia 347
SG - Singapore 279
HK - Hong Kong 252
CN - Cina 233
DE - Germania 115
IN - India 113
UA - Ucraina 96
FI - Finlandia 90
JO - Giordania 74
GB - Regno Unito 65
VN - Vietnam 64
CH - Svizzera 53
CI - Costa d'Avorio 26
TH - Thailandia 24
FR - Francia 21
ES - Italia 19
CA - Canada 16
TR - Turchia 14
KR - Corea 12
JP - Giappone 9
BE - Belgio 7
NL - Olanda 7
SC - Seychelles 5
GR - Grecia 3
RO - Romania 3
AU - Australia 2
BR - Brasile 2
CO - Colombia 2
CZ - Repubblica Ceca 2
LT - Lituania 2
TW - Taiwan 2
AE - Emirati Arabi Uniti 1
AM - Armenia 1
BG - Bulgaria 1
DK - Danimarca 1
DZ - Algeria 1
EU - Europa 1
HR - Croazia 1
IL - Israele 1
KH - Cambogia 1
LI - Liechtenstein 1
MX - Messico 1
PE - Perù 1
PK - Pakistan 1
RS - Serbia 1
TN - Tunisia 1
UG - Uganda 1
Totale 14.925
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Città #
Warsaw 2.914
Santa Clara 1.395
Fairfield 933
Ashburn 539
Dublin 484
Chandler 479
Woodbridge 415
Cambridge 368
Seattle 340
Wilmington 322
Houston 315
Florence 283
Singapore 232
Hong Kong 166
Altamura 153
Jacksonville 145
Lawrence 142
Princeton 126
Ann Arbor 114
Mumbai 93
Beijing 80
Buffalo 79
Moscow 71
Boardman 68
Boston 68
Medford 63
Shanghai 61
San Diego 58
Dong Ket 54
Bern 50
New York 42
Abidjan 26
Ron Phibun 24
Norwalk 23
Phoenix 23
Helsinki 19
Kent 19
Washington 19
Hillsboro 18
Los Angeles 17
Menlo Park 17
Milan 16
London 15
Barcelona 14
West Jordan 14
Bremen 13
Falls Church 13
Pune 13
Izmir 12
Andover 11
Redwood City 11
Redmond 10
Saronno 10
Prato 9
Dearborn 8
Rome 8
Toronto 8
Bari 7
Brussels 7
Lappeenranta 7
Cagliari 6
Detroit 6
Naples 6
Paris 6
Tappahannock 6
Yubileyny 6
Auburn Hills 5
Laurel 5
Lucca 5
Munich 5
Nanjing 5
Seoul 5
Tokyo 5
Troy 5
Montréal 4
Romola 4
Siena 4
Verona 4
Albignasego 3
Amsterdam 3
Bagno A Ripoli 3
Civitella in Val di Chiana 3
Cleveland 3
Esslingen am Neckar 3
Frankfurt Am Main 3
Frankfurt am Main 3
Guangzhou 3
Mascalucia 3
Modena 3
Napoli 3
Pisa 3
Renton 3
San Mateo 3
Shaoxing 3
Suzhou 3
Vinci 3
Wuhan 3
Alfter 2
Anguillara Sabazia 2
Arezzo 2
Totale 11.218
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Nome #
Effect of IR laser on myoblasts: a proteomic study 294
Acylphosphatase Is a Strong Apoptosis Inducer in HeLa Cell Line 276
Catechol-Containing Hydroxylated Biomimetic 4-Thiaflavanes as Inhibitors of Amyloid Aggregation 270
A nucleophilic catalysis step is involved in the hydrolysis of aryl phosphate monoesters by human CT acylphosphatase 266
A single amino acid mutation affects elicitor and expansins-like activities of cerato-platanin, a non-catalytic fungal protein. 265
Acylphosphatase possesses nucleoside triphosphatase and nucleoside diphosphatase activities 264
Cloning of murine low molecular weight phosphotyrosine protein phosphatase cDNA: identification of a new isoform 260
HYDROGEN PEROXIDE TRIGGERS THE FORMATION OF A DISULFIDE DIMER OF MUSCLE ACYLPHOSPHATASE AND MODIFIES SOME FUNCTIONAL PROPERTIES OF THE ENZYME 256
The in vivo tyrosine phosphorylation level of yeast immunophilin Fpr3 is influenced by the LMW-PTP Ltp1. 255
The effects of CA IX catalysis products within tumor microenvironment 246
Porcine liver low M(r) phosphotyrosine protein phosphatase: the amino acid sequence 237
Mechanism of acylphosphatase inactivation by Woodward's reagent K 236
Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTPe1B: In vitro, in silico, and in vivo approaches 221
The contribution of acidic residues to the conformational stability of common-type acylphosphatase 221
New 4-[(5-arylidene-2-arylimino-4-oxo-3-thiazolidinyl)methyl]benzoic acids active as protein tyrosine phosphatase inhibitors endowed with insulinomimetic effect on mouse C2C12 skeletal muscle cells 216
New concepts about fibroblasts trophic function 213
Synthesis, in vitro and in silico screening of ethyl 2-(6-substituted benzo[d]thiazol-2-ylamino)-2-oxoacetates as protein-tyrosine phosphatase 1B inhibitors. 208
Targeting LMW-PTP to sensitize melanoma cancer cells toward chemo- and radiotherapy. 206
Thermodynamics and kinetics of folding of common type acylphosphatase 206
Highly Charged Ruthenium(II) Polypyridyl Complexes as Effective Photosensitizer in Photodynamic Therapy 199
LMW-PTP targeting potentiates the effects of drugs used in chronic lymphocytic leukemia therapy 183
Honey extracts inhibit PTP1B, upregulate insulin receptor expression, and enhance glucose uptake in human HepG2 cells 181
Effect of natural compounds on insulin signaling. 174
Development of Light-Responsive Liquid Crystalline Elastomers to Assist Cardiac Contraction 167
miR-210-3p mediates metabolic adaptation and sustains DNA damage repair of resistant colon cancer cells to treatment with 5-fluorouracil 166
Study on a fermented whole wheat: Phenolic content, activity on PTP1B enzyme and in vitro prebiotic properties 163
5-Fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like trait 162
Low molecular weight protein tyrosine phosphatase: Multifaceted functions of an evolutionarily conserved enzyme 150
Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair 148
In depth study of phenolic profile and PTP-1B inhibitory power of cold-pressed grape seed oils of different varieties 147
LMW-PTP modulates glucose metabolism in cancer cells 146
Cell instructive Liquid Crystalline Networks for myotube formation 146
Liquid Crystal-Induced Myoblast Alignment 144
The functionalization of nanostructured carbon materials for biological application 142
The insulin-mimetic effect of Morin: A promising molecule in diabetes treatment 141
Human Acid β-Glucosidase Inhibition by Carbohydrate Derived Iminosugars: Towards New Pharmacological Chaperones for Gaucher Disease 140
The ”click-on-tube” approach for the production of efficient drug carriers based on oxidize multiwalled carbon nanotubes 137
2-Methoxybenzoyl phosphate: a new substrate for continuous fluorimetric and spectrophotometric acyl phosphatase assays 135
Azido-Substituted BODIPY Dyes for the Production of Fluorescent Carbon Nanotubes 134
Multiwalled carbon nanotubes for combination therapy: a biodistribution and efficacy pilot study 134
Design and evaluation of non-carboxylate 5-arylidene-2-thioxo-4-imidazolidinones as novel non-competitive inhibitors of protein tyrosine phosphatase 1B 134
S-Homocysteinylation effects on transthyretin: worsening of cardiomyopathy onset 133
Multiwalled carbon nanotubes for drug delivery: Efficiency related to length and incubation time 133
Effect of selected strains of lactobacilli on the antioxidant and anti-inflammatory properties of sourdough 133
Cancer associated fibroblasts transfer lipids and proteins to cancer cells through cargo vesicles supporting tumor growth 129
Does Fermentation Really Increase the Phenolic Content in Cereals? A Study on Millet 129
Dual targeting of PTP1B and glucosidases with new bifunctional iminosugar inhibitors to address type 2 diabetes 127
Evidence for a multivalent effect in inhibition of sulfatases involved in lysosomal storage disorders (LSDs) 126
Morin: A Promising Natural Drug 126
Anoikis molecular pathways and its role in cancer progression. 126
An investigation on 4-thiazolidinone derivatives as dual inhibitors of aldose reductase and protein tyrosine phosphatase 1B, in the search for potential agents for the treatment of type 2 diabetes mellitus and its complications 124
Metformin salts with oxidized multiwalled carbon nanotubes: In vitro biological activity and inhibition of CNT internalization 120
Low Molecular Weight-Protein Tyrosine Phosphatase and Caveolin-1: Interaction and Isoenzyme-Dependent Regulation 118
INSULIN INHIBITS PLATELET-DERIVED GROWTH FACTOR-INDUCED CELL PROLIFERATION 118
SITE-DIRECTED MUTAGENESIS OF TWO AROMATIC RESIDUES LINING THE ACTIVE SITE POCKET OF THE YEAST LTP1 117
Common-type acylphosphatase: steady-state kinetics and leaving-group dependence. 117
Protective effect of new S-acylglutathione derivatives against amyloid induced oxidative stress 112
Stereoselective Synthesis of C‑2 Alkylated Trihydroxypiperidines: Novel Pharmacological Chaperones for Gaucher Disease 110
Protein N-homocysteinylation induces the formation of toxic amyloid-like protofibrils 109
Morin-dependent inhibition of low molecular weight protein tyrosine phosphatase (LMW-PTP) restores sensitivity to apoptosis during colon carcinogenesis: Studies in vitro and in vivo, in an Apc-driven model of colon cancer 109
Synthesis, biological activity and structure activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells 107
5-Arylidene-2phenylimino-4-thiazolidinones as PTP1B and LMW-PTP inhibitors 107
Discovery of 4-[(5-arylidene-4-oxothiazolidin-3-yl)methyl]benzoic acid derivatives active as novel potent allosteric inhibitors of protein tyrosine phosphatase 1B: In silico studies and in vitro evaluation as insulinomimetic and anti-inflammatory agents 107
Design of Biocompatible Liquid Cristal Elastomers Reproducing the Mechanical Properties of Human Cardiac Muscle 107
Antioxidant and anti-inflammatory properties of sourdoughs containing selected Lactobacilli strains are retained in breads 105
Oncogenic Tyrosine Phosphatases: Novel Therapeutic Targets for Melanoma Treatment 105
uPAR-expressing melanoma exosomes promote angiogenesis by VE-Cadherin, EGFR and uPAR overexpression and rise of ERK1,2 signaling in endothelial cells 104
Glucocerebrosidase (GCase) activity modulation by 2-alkyl trihydroxypiperidines: Inhibition and pharmacological chaperoning 103
3,4,5-Trihydroxypiperidine Based Multivalent Glucocerebrosidase (GCase) Enhancers 102
Regulation of glucose metabolism by bioactive phytochemicals for the management of type 2 diabetes mellitus. 100
Structure-Based Optimization of Benzoic Acids as Inhibitors of Protein Tyrosine Phosphatase 1B and Low Molecular Weight Protein Tyrosine Phosphatase 96
Lscβ and lscγ, two novel levansucrases of Pseudomonas syringae pv. actinidiae biovar 3, the causal agent of bacterial canker of kiwifruit, show different enzymatic properties 95
Synthesis and evaluation of thiazolidine-2,4-dione/benzazole derivatives as inhibitors of protein tyrosine phosphatase 1B (PTP-1B): Antihyperglycemic activity with molecular docking study 94
Bioactive Properties of Breads Made with Sourdough of Hull-Less Barley or Conventional and Pigmented Wheat Flours 93
PrPc activation induces neurite outgrowth and differentiation in PC12 cells: role for caveolin-1 in the signal transduction pathway 91
Synthesis, activity and molecular modeling of a new series of chromones as low molecular weight protein tyrosine phosphatase inhibitors 91
Design, synthesis, in vitro, in vivo and in silico pharmacological characterization of antidiabetic N-Boc-L-tyrosine-based compounds 91
Identifying Human PTP1B Enzyme Inhibitors from Marine Natural Products: Perspectives for Developing of Novel Insulin-Mimetic Drugs 89
Synthesis, in vitro and computational studies of protein tyrosine phosphatase 1B inhibition of a small library of 2-arylsulfonylaminobenzothiazoles with antihyperglycemic activity 88
Photoswitchable inhibitors of human β-glucocerebrosidase 88
Tumor microenvironment and metabolism in prostate cancer. 83
SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis 82
A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity 81
Role of tyrosine phosphorylation in modulating cancer cell metabolism 80
Dietary polyphenols as antidiabetic agents: Advances and opportunities 80
5-Arylidene- 2,4-Thiazolidinediones Inhibitors of Protein Tyrosine Phosphatases 78
Caveolin-1 inhibits LMW-PTP isoenzymes catalytic activity 78
Activated fibroblasts enhance cancer cell migration by microvesicles-mediated transfer of Galectin-1 78
Studying the trafficking of labeled trodusquemine and its application as nerve marker for light-sheet and expansion microscopy 75
In vitro and in silico PTP-1B inhibition and in vivo antidiabetic activity of semisynthetic moronic acid derivatives 75
Metabolic Reprogramming in Anticancer Drug Resistance: A Focus on Amino Acids 74
Ruthenium(II) polypyridyl complexes as versatile tools in the design of photoresponsive compounds for biological applications 73
Insulin inhibits platelet-derived growth factor-induced cell proliferation 73
Identification of RPTPalpha as responsible for Fyn activation in PrPc signalling 72
Fibroblasts transfer lipids and proteins to tumor cells through cargo vescicles supporting their growth 71
In search for multi-target ligands as potential agents for diabetes mellitus and its complications—a structure-activity relationship study on inhibitors of aldose reductase and protein tyrosine phosphatase 1b 69
Homocysteine induces insulin fibrillation and loss of function: a possible link with both insulin resistance and cutaneous amyloidosis 68
Structure-activity relationships in a series of auranofin analogues showing remarkable antiproliferative properties 68
Effect of the non ionic detergent Triton X-100 on the activity of IF1and IF2, two human LMW-PTP isoenzymes 66
Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition 65
Totale 13.757
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Categoria #
all - tutte 39.972
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.972
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.636 0 0 0 0 0 285 271 329 263 185 263 40
2020/20211.817 145 164 87 203 87 170 91 144 191 317 92 126
2021/2022960 37 83 63 66 31 69 42 57 40 61 191 220
2022/20232.274 219 419 108 153 161 369 304 153 230 14 68 76
2023/20241.102 24 98 142 59 99 190 81 243 9 61 60 36
2024/20253.883 175 623 371 991 1.669 54 0 0 0 0 0 0
Totale 15.153