CHITI, FABRIZIO
 Distribuzione geografica
Continente #
NA - Nord America 3491
EU - Europa 1374
AS - Asia 622
AF - Africa 66
OC - Oceania 56
SA - Sud America 39
Continente sconosciuto - Info sul continente non disponibili 1
Totale 5649
Nazione #
US - Stati Uniti d'America 3397
IT - Italia 278
CN - Cina 236
GB - Regno Unito 196
IE - Irlanda 185
DE - Germania 163
PL - Polonia 127
IN - India 102
VN - Vietnam 102
CA - Canada 87
NL - Olanda 86
FR - Francia 72
AU - Australia 56
ZA - Sudafrica 54
JP - Giappone 51
ES - Italia 45
CZ - Repubblica Ceca 33
RU - Federazione Russa 29
CL - Cile 23
BE - Belgio 22
SE - Svezia 21
PT - Portogallo 19
RO - Romania 19
IR - Iran 17
SG - Singapore 17
HK - Hong Kong 16
KR - Corea 14
IL - Israele 13
DK - Danimarca 12
FI - Finlandia 11
IQ - Iraq 10
UA - Ucraina 9
BR - Brasile 8
CH - Svizzera 8
SA - Arabia Saudita 8
TW - Taiwan 8
ID - Indonesia 7
LT - Lituania 7
MX - Messico 7
NG - Nigeria 7
AE - Emirati Arabi Uniti 6
AT - Austria 6
GR - Grecia 6
NO - Norvegia 6
AR - Argentina 5
EG - Egitto 4
MO - Macao, regione amministrativa speciale della Cina 4
HU - Ungheria 3
MY - Malesia 3
BY - Bielorussia 2
LV - Lettonia 2
MT - Malta 2
PK - Pakistan 2
SI - Slovenia 2
TR - Turchia 2
BG - Bulgaria 1
CO - Colombia 1
EE - Estonia 1
EU - Europa 1
HR - Croazia 1
JO - Giordania 1
KH - Cambogia 1
MA - Marocco 1
PE - Perù 1
QA - Qatar 1
SR - Suriname 1
TH - Thailandia 1
Totale 5649
Città #
Fairfield 377
Santa Cruz 294
Buffalo 274
Houston 258
Seattle 228
Woodbridge 215
Cambridge 180
Dublin 179
Ashburn 170
Warsaw 119
Wilmington 110
Dong Ket 84
Ann Arbor 83
Florence 76
Mountain View 52
Beijing 51
Wuhan 49
University Park 45
Muizenberg 41
Las Vegas 40
Clearwater 35
Chicago 33
Phoenix 33
Bengaluru 27
Ottawa 27
New York 26
Shanghai 23
San Diego 21
Los Angeles 19
Minneapolis 19
Dallas 17
Riva 17
Guangzhou 16
Henderson 16
Lake Forest 14
London 14
Toronto 14
Bordeaux 13
Bremen 13
Fleming Island 12
Austin 11
Memphis 11
Pisa 11
San Francisco 11
Singapore 11
Baltimore 10
Des Moines 10
Hanoi 10
Sydney 10
Utrecht 10
Barcelona 9
Tokyo 9
Anghiari 8
Boardman 8
Castelliri 8
Changsha 8
Council Bluffs 8
Duncan 8
Irvine 8
Kansas City 8
Melbourne 8
Munich 8
Napoli 8
Padova 8
Saint Petersburg 8
Southampton 8
Amsterdam 7
Central 7
Easton 7
Hobart 7
Paris 7
Rhoon 7
Santiago 7
Taipei 7
Andover 6
Bangalore 6
Berlin 6
Bhubaneswar 6
Boston 6
Boulder 6
Diegem 6
Durham 6
Guiyang 6
Hangzhou 6
Jacksonville 6
Jakarta 6
Kumar 6
Leeds 6
Mississauga 6
Nanjing 6
Provo 6
Rochester 6
Rome 6
Saint Louis 6
Sint Odilienberg 6
Sint-truiden 6
Wageningen 6
Boynton Beach 5
Changchun 5
Delhi 5
Totale 3778
Nome #
Protein misfolding, amyloid formation, and human disease: A summary of progress over the last decade, file e398c381-5047-179a-e053-3705fe0a4cff 511
A causative link between the structure of aberrant protein oligomers and their toxicity, file e398c378-b3de-179a-e053-3705fe0a4cff 451
Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers, file e398c381-2859-179a-e053-3705fe0a4cff 366
Soluble Oligomers Require a Ganglioside to Trigger Neuronal Calcium Overload, file e398c37c-38cf-179a-e053-3705fe0a4cff 327
Patterns of cell death triggered in two different cell lines by HypF-N prefibrillar aggregates., file e398c378-955b-179a-e053-3705fe0a4cff 207
The contribution of acidic residues to the conformational stability of common-type acylphosphatase, file e398c378-9199-179a-e053-3705fe0a4cff 182
The Folding process of Human Profilin-1, a novel protein associated with familial amyotrophic lateral sclerosis, file e398c379-5353-179a-e053-3705fe0a4cff 159
Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia, file e398c37b-d25c-179a-e053-3705fe0a4cff 151
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity, file e398c37b-a4f1-179a-e053-3705fe0a4cff 146
Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions, file e398c37b-e1f9-179a-e053-3705fe0a4cff 146
Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases, file e398c37b-9ff3-179a-e053-3705fe0a4cff 137
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes, file e398c37d-de56-179a-e053-3705fe0a4cff 136
Probing the origin of the toxicity of oligomeric aggregates of α-synuclein with antibodies, file e398c37e-624e-179a-e053-3705fe0a4cff 136
Insight into the structure of amyloid fibrils from the analysis of globular proteins, file e398c37a-405e-179a-e053-3705fe0a4cff 135
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells, file e398c37b-a4b0-179a-e053-3705fe0a4cff 134
Effect of molecular chaperones on aberrant protein oligomers in vitro: super- versus sub-stoichiometric chaperone concentrations, file e398c37b-db9c-179a-e053-3705fe0a4cff 130
Identification of Novel 1,3,5-Triphenylbenzene Derivative Compounds as Inhibitors of Hen Lysozyme Amyloid Fibril Formation, file e398c37e-944e-179a-e053-3705fe0a4cff 129
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells, file e398c378-f70d-179a-e053-3705fe0a4cff 121
Capturing Aβ42 aggregation in the cell, file e398c37d-fee9-179a-e053-3705fe0a4cff 121
Large proteins have a great tendency to aggregate but a low propensity to form amyloid fibrils, file e398c37a-4b72-179a-e053-3705fe0a4cff 119
Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy, file e398c37b-dfe1-179a-e053-3705fe0a4cff 114
Chaperones in Neurodegeneration, file e398c37a-701d-179a-e053-3705fe0a4cff 111
A computational approach for identifying the chemical factors involved in the glycosaminoglycans-mediated acceleration of amyloid fibril formation, file e398c37a-42d6-179a-e053-3705fe0a4cff 108
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells, file e398c37b-d4e5-179a-e053-3705fe0a4cff 103
The N-terminal helix controls the transition between the soluble and amyloid states of an FF domain., file e398c37a-5643-179a-e053-3705fe0a4cff 98
Partial Failure of Proteostasis Systems Counteracting TDP-43 Aggregates in Neurodegenerative Diseases, file e398c37e-9cdd-179a-e053-3705fe0a4cff 98
Quantification of the Relative Contributions of Loss-of function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies, file e398c37b-a4ab-179a-e053-3705fe0a4cff 94
Backbone NMR assignments of HypF-N under conditions generating toxic and non-toxic oligomers, file e398c37d-a842-179a-e053-3705fe0a4cff 94
Aggregation propensity of the human proteome, file e398c37a-3f88-179a-e053-3705fe0a4cff 91
Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicity, file e398c37a-3ffb-179a-e053-3705fe0a4cff 84
Toxic HypF-N oligomers selectively bind the plasma membrane to impair cell adhesion capability, file e398c37e-99f9-179a-e053-3705fe0a4cff 78
Nanoscopic insights into the surface conformation of neurotoxic amyloid b oligomers, file e398c37f-83ec-179a-e053-3705fe0a4cff 62
The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells, file e398c381-6775-179a-e053-3705fe0a4cff 60
Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism, file e398c380-3498-179a-e053-3705fe0a4cff 58
Chaperones as Suppressors of Protein Misfolded Oligomer Toxicity, file e398c37f-015a-179a-e053-3705fe0a4cff 57
Probing conformational changes of monomeric transthyretin with second derivative fluorescence, file e398c37f-e67b-179a-e053-3705fe0a4cff 54
Soluble Prion peptide 107–120 protects neuroblastoma SH-SY5Y cells against oligomers associated with Alzheimer’s disease, file e398c380-1e71-179a-e053-3705fe0a4cff 54
Stability of an aggregation-prone partially folded state of human profilin-1 correlates with aggregation propensity, file e398c37d-a844-179a-e053-3705fe0a4cff 51
Thermodynamics and kinetics of folding of common type acylphosphatase, file e398c378-8b7d-179a-e053-3705fe0a4cff 48
Homage to Chris Dobson, file e398c380-1538-179a-e053-3705fe0a4cff 41
Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers, file e398c37c-aeff-179a-e053-3705fe0a4cff 37
Amyloid fibrils act as a reservoir of soluble oligomers, the main culprits in protein deposition diseases, file b874e5ce-3aa3-4310-99d2-e82ed99c889b 36
Small molecule protein binding to correct cellular folding or stabilize the native state against misfolding and aggregation, file ab1d5478-d4c6-40c5-9842-a7b546304310 34
Cloning, expression and characterization of a new human LMW-PTP isoform originating by alternative splicing, file e398c378-950c-179a-e053-3705fe0a4cff 34
Molecular links between aberrant protein oligomers and neurodegeneration in Alzheimer’s disease, file e398c37b-a5d6-179a-e053-3705fe0a4cff 31
Sphingosine 1-phosphate attenuates neuronal dysfunction induced by amyloid-β oligomers through endocytic internalization of NMDA receptors, file 469d176f-7b4a-40b4-b914-7dd8103eb913 30
Making biological membrane resistant to the toxicity of misfolded protein oligomers: a lesson from trodusquemine, file 96185b7c-60c4-427b-aad6-d7dd27eeff43 29
Squalamine and its derivatives modulate the aggregation of amyloid-β and α-synuclein and suppress the toxicity of their oligomers, file e398c381-814f-179a-e053-3705fe0a4cff 29
Single particle tracking to study the binding of protein misfolded oligomer to membrane ganglioside GM1, file e398c37b-9f1f-179a-e053-3705fe0a4cff 28
Looking for residues involved in the muscle acylphosphatase catalytic mechanism and structural stabilization: role of Asn41, Ther42 and Thr46, file e398c378-b2ce-179a-e053-3705fe0a4cff 24
A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43, file 3c046775-2499-4dfb-8ac3-79be4811ffad 23
Urea titration of a lipase from Pseudomonas sp. reveals four different conformational states, with a stable partially folded state explaining its high aggregation propensity, file 6e45af78-546e-4636-8ec4-1687ea0ee4b3 18
Multistep Inhibition of α‑Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine, file e398c37d-7b95-179a-e053-3705fe0a4cff 18
Misfolded protein oligomers induce an increase of intracellular Ca2+ causing an escalation of reactive oxidative species, file 37ec0f86-dbc8-4919-8ac7-b0287cffde83 9
Quantitative Measurement of the Affinity of Toxic and Nontoxic Misfolded Protein Oligomers for Lipid Bilayers and of its Modulation by Lipid Composition and Trodusquemine, file 51e5654f-4b60-4086-9db0-2a4a10f8bdbb 7
Multistep Inhibition of α‑Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine, file e398c381-7c02-179a-e053-3705fe0a4cff 6
Distinct responses of human peripheral blood cells to different misfolded protein oligomers, file 1220483e-e090-4118-8b42-d3cbf0349667 5
Conversion of the Native N-Terminal Domain of TDP-43 into a Monomeric Alternative Fold with Lower Aggregation Propensity, file 71778391-8e07-4058-9703-be2b1cc33e0b 5
Exogenous misfolded protein oligomers can cross the intestinal barrier and cause a disease phenotype in C. elegans, file 7cbac64d-4a11-41d1-a2ca-8dba546ab1ff 5
Biophysical characterization of full length TAR DNA-Binding Protein (TDP-43) phase separation, file e4e41f7c-7fab-442f-974b-ef0ca3b6aeff 5
Full-length TDP-43 and its C-terminal domain form filaments in vitro having non-amyloid properties, file 7dbd0e4b-007c-492d-8f12-adff1379560d 4
Squalamine and trodusquemine: two natural products for neurodegenerative diseases, from physical chemistry to the clinic, file 935afeee-5831-47a3-b6fb-4bdce5d92630 4
Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers, file e398c378-bf91-179a-e053-3705fe0a4cff 2
Glycosaminoglycans (GAGs) Suppress the Toxicity of HypF-N Prefibrillar Aggregates, file e398c378-db1b-179a-e053-3705fe0a4cff 2
Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers, file e398c378-db1c-179a-e053-3705fe0a4cff 2
The polyphenol Oleuropein aglycone hinders the growth of toxic transthyretin amyloid assemblies, file e398c37b-1be1-179a-e053-3705fe0a4cff 2
A comparison of the biochemical modifications caused by toxic and non-toxic protein oligomers in cells, file e398c378-b3fe-179a-e053-3705fe0a4cff 1
Transthyretin suppresses the toxicity of oligomers formed by misfolded proteins in vitro, file e398c378-df1b-179a-e053-3705fe0a4cff 1
Extracellular chaperones prevent Aβ42-induced toxicity in rat brains, file e398c378-e3a1-179a-e053-3705fe0a4cff 1
Toxicity of Protein Oligomers Is Rationalized by a Function Combining Size and Surface Hydrophobicity, file e398c378-f3b2-179a-e053-3705fe0a4cff 1
A Complex Equilibrium among Partially Unfolded Conformations in Monomeric Transthyretin, file e398c378-fb29-179a-e053-3705fe0a4cff 1
Protein misfolding, amyloid formation, and human disease: A summary of progress over the last decade, file e398c37c-8be3-179a-e053-3705fe0a4cff 1
Totale 5937
Categoria #
all - tutte 7774
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 7774


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2017/201840 0000 00 08 131045
2018/2019616 5181411 155 1057 77103143158
2019/20201182 110995993 137120 10499 133729858
2020/2021922 75953878 8170 5759 887410899
2021/20221673 1315868123 318107 105147 9768318133
2022/20231289 6789304269 127158 2750 0000
Totale 5937