CHITI, FABRIZIO
 Distribuzione geografica
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Continente #
NA - Nord America 17.802
EU - Europa 13.680
AS - Asia 7.231
SA - Sud America 920
Continente sconosciuto - Info sul continente non disponibili 305
AF - Africa 216
OC - Oceania 155
Totale 40.309
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Nazione #
US - Stati Uniti d'America 17.516
PL - Polonia 4.370
RU - Federazione Russa 3.242
IT - Italia 2.266
SG - Singapore 1.964
CN - Cina 1.790
HK - Hong Kong 1.040
IE - Irlanda 864
VN - Vietnam 794
BR - Brasile 725
SE - Svezia 711
KR - Corea 626
DE - Germania 546
FI - Finlandia 359
IN - India 330
UA - Ucraina 320
FR - Francia 307
GB - Regno Unito 251
CA - Canada 171
AU - Australia 144
BD - Bangladesh 140
NL - Olanda 126
CH - Svizzera 110
ID - Indonesia 105
JP - Giappone 80
ES - Italia 63
JO - Giordania 58
TR - Turchia 57
AR - Argentina 55
CI - Costa d'Avorio 40
MX - Messico 40
ZA - Sudafrica 36
EC - Ecuador 35
IQ - Iraq 35
NG - Nigeria 31
CO - Colombia 30
UZ - Uzbekistan 25
CL - Cile 23
BE - Belgio 22
MA - Marocco 20
PH - Filippine 20
PK - Pakistan 20
AE - Emirati Arabi Uniti 17
PY - Paraguay 17
EG - Egitto 16
LT - Lituania 16
SC - Seychelles 16
JM - Giamaica 15
VE - Venezuela 15
IR - Iran 14
RO - Romania 14
KE - Kenya 13
SA - Arabia Saudita 13
AZ - Azerbaigian 12
IL - Israele 12
MY - Malesia 12
TT - Trinidad e Tobago 12
AT - Austria 11
BG - Bulgaria 11
BJ - Benin 11
NZ - Nuova Zelanda 11
SK - Slovacchia (Repubblica Slovacca) 11
CR - Costa Rica 10
HN - Honduras 10
TH - Thailandia 10
KZ - Kazakistan 9
PE - Perù 9
TN - Tunisia 9
AL - Albania 8
HU - Ungheria 8
PT - Portogallo 8
DZ - Algeria 7
PA - Panama 7
BO - Bolivia 6
CZ - Repubblica Ceca 6
DK - Danimarca 6
KG - Kirghizistan 6
NP - Nepal 6
TW - Taiwan 6
GE - Georgia 5
GT - Guatemala 5
UY - Uruguay 5
AM - Armenia 4
BA - Bosnia-Erzegovina 4
BH - Bahrain 4
CM - Camerun 4
DO - Repubblica Dominicana 4
ET - Etiopia 4
GR - Grecia 4
HR - Croazia 4
LB - Libano 4
LU - Lussemburgo 3
MU - Mauritius 3
NI - Nicaragua 3
PR - Porto Rico 3
SV - El Salvador 3
SY - Repubblica araba siriana 3
XK - ???statistics.table.value.countryCode.XK??? 3
GA - Gabon 2
IS - Islanda 2
Totale 39.983
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Città #
Warsaw 4.356
Santa Clara 3.213
Ashburn 2.129
Fairfield 1.527
Singapore 1.395
Hong Kong 867
Dublin 863
Chandler 810
Woodbridge 719
Seattle 648
Seoul 607
San Jose 597
Cambridge 578
Houston 568
Wilmington 547
Jacksonville 498
Milan 463
Council Bluffs 456
Hefei 428
Beijing 356
Ann Arbor 256
Altamura 248
The Dalles 243
Florence 239
Ho Chi Minh City 232
Lawrence 219
Los Angeles 209
Princeton 209
Rome 189
Lauterbourg 185
Buffalo 183
Boardman 163
Boston 161
Moscow 147
Mumbai 140
Hanoi 137
Bremen 129
Melbourne 128
Helsinki 118
Munich 115
Phoenix 113
Dong Ket 106
New York 100
Dallas 92
San Diego 90
Jakarta 86
Naples 81
Pune 78
Kent 72
Shanghai 69
Medford 68
Bern 56
Paris 56
São Paulo 55
Columbus 54
Turku 51
Clifton 48
Tokyo 46
Turin 45
Lappeenranta 41
Abidjan 40
Norwalk 39
Toronto 37
Bologna 35
Izmir 34
London 34
Orem 33
Chicago 32
Da Nang 31
Guangzhou 31
Montreal 31
Redondo Beach 30
Haiphong 29
Abuja 28
Auburn Hills 27
Barcelona 26
Brooklyn 26
Bengaluru 25
Figino 25
Tashkent 25
West Jordan 24
Frankfurt am Main 23
Philadelphia 22
Concord 21
Sabadell 21
Atlanta 20
Venice 20
Zurich 20
Andover 19
Brescia 19
Hillsboro 19
Miano 19
Bari 18
Brasília 18
Chennai 18
Denver 18
Verona 18
Basel 17
Falls Church 17
Genoa 17
Totale 27.688
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Nome #
Protein misfolding, amyloid formation, and human disease: A summary of progress over the last decade 739
(1)H, (13)C and (15)N resonance assignments of human muscle acylphosphatase 565
A causative link between the structure of aberrant protein oligomers and their toxicity 490
Insight into the structure of amyloid fibrils from the analysis of globular proteins 373
Aggregation propensity of the human proteome 359
Large proteins have a great tendency to aggregate but a low propensity to form amyloid fibrils 358
A computational approach for identifying the chemical factors involved in the glycosaminoglycans-mediated acceleration of amyloid fibril formation 353
The Folding process of Human Profilin-1, a novel protein associated with familial amyotrophic lateral sclerosis 352
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 335
Cloning, expression and characterization of a new human LMW-PTP isoform originating by alternative splicing 333
Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers 332
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity 330
Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases 328
Soluble Oligomers Require a Ganglioside to Trigger Neuronal Calcium Overload 317
Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia 317
Quantification of the Relative Contributions of Loss-of function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies 316
Effect of molecular chaperones on aberrant protein oligomers in vitro: super- versus sub-stoichiometric chaperone concentrations 315
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 315
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 307
Patterns of cell death triggered in two different cell lines by HypF-N prefibrillar aggregates. 305
Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy 299
The N-terminal helix controls the transition between the soluble and amyloid states of an FF domain. 283
Toxic HypF-N oligomers selectively bind the plasma membrane to impair cell adhesion capability 282
Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions 273
Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicity 271
Looking for residues involved in the muscle acylphosphatase catalytic mechanism and structural stabilization: role of Asn41, Ther42 and Thr46 266
The contribution of acidic residues to the conformational stability of common-type acylphosphatase 265
Molecular links between aberrant protein oligomers and neurodegeneration in Alzheimer’s disease 265
Thermodynamics and kinetics of folding of common type acylphosphatase 263
Chaperones in Neurodegeneration 261
Multistep Inhibition of α‑Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine 255
Single particle tracking to study the binding of protein misfolded oligomer to membrane ganglioside GM1 254
The toxicity of misfolded protein oligomers is independent of their secondary structure 248
Partial Failure of Proteostasis Systems Counteracting TDP-43 Aggregates in Neurodegenerative Diseases 248
Backbone NMR assignments of HypF-N under conditions generating toxic and non-toxic oligomers 242
Capturing Aβ42 aggregation in the cell 231
Isolation and characterization of soluble human full-length TDP-43 associated with neurodegeneration 224
Nanoscopic insights into the surface conformation of neurotoxic amyloid b oligomers 223
Identification of Novel 1,3,5-Triphenylbenzene Derivative Compounds as Inhibitors of Hen Lysozyme Amyloid Fibril Formation 222
The induction of α-helical structure in partially unfolded HypF-N does not affect its aggregation propensity 220
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes 218
PROTEIN AGGREGATION STARTING FROM THE NATIVE GLOBULAR STATE 216
Amyloid Fibril Formation can Proceed from Different Conformations of a Partially Unfolded Protein 215
Assessing the role of aromatic residues in the amyloid aggregation of human muscle acylphosphatase 215
Chaperones as Suppressors of Protein Misfolded Oligomer Toxicity 214
Making biological membrane resistant to the toxicity of misfolded protein oligomers: a lesson from trodusquemine 213
Amyloid fibril formation and disaggregation of fragment 1-29 of apomyoglobin: insights into the effect of pH on protein fibrillogenesis 213
Amyloid fibrils act as a reservoir of soluble oligomers, the main culprits in protein deposition diseases 212
Amyloid formation from HypF-N under conditions in which the protein is initially in its native state 210
Biological function in a non-native partially folded state of a protein. 208
Direct Conversion of an Enzyme from Native-like to Amyloid-like Aggregates within Inclusion Bodies 208
Biophysical characterization of full-length TAR DNA-binding protein (TDP-43) phase separation. 204
Stability of an aggregation-prone partially folded state of human profilin-1 correlates with aggregation propensity 204
Sphingosine 1-phosphate attenuates neuronal dysfunction induced by amyloid-β oligomers through endocytic internalization of NMDA receptors 203
A Complex Equilibrium among Partially Unfolded Conformations in Monomeric Transthyretin 203
Conversion of the Native N-Terminal Domain of TDP-43 into a Monomeric Alternative Fold with Lower Aggregation Propensity 202
Amyloidogenesis in its biological environment: challenging a fundamental issue in protein misfolding diseases. 202
A comparison of the biochemical modifications caused by toxic and non-toxic protein oligomers in cells 200
Amyloid-β oligomer synaptotoxicity is mimicked by oligomers of the model protein HypF-N 200
An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature 198
Probing conformational changes of monomeric transthyretin with second derivative fluorescence 198
Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers 197
Studying the trafficking of labeled trodusquemine and its application as nerve marker for light-sheet and expansion microscopy 196
Characterizing intermolecular interactions that initiate native-like protein aggregation. 195
A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43 194
Evidence for a mechanism of amyloid formation involving molecular reorganisation within native-like precursor aggregates 194
Mutations of Profilin-1 Associated with Amyotrophic Lateral Sclerosis Promote Aggregation Due to Structural Changes of Its Native State 193
Quantitative Measurement of the Affinity of Toxic and Nontoxic Misfolded Protein Oligomers for Lipid Bilayers and of its Modulation by Lipid Composition and Trodusquemine 191
A model for the aggregation of the acylphosphatase from Sulfolobus solfataricus in its native-like state. 190
Sequence and structural determinants of amyloid fibril formation 189
Glycosaminoglycans (GAGs) Suppress the Toxicity of HypF-N Prefibrillar Aggregates 188
C-terminal region contributes to muscle acylphosphatase three-dimensional structure stabilisation 187
Full-length TDP-43 and its C-terminal domain form filaments in vitro having non-amyloid properties 186
The polyphenol Oleuropein aglycone hinders the growth of toxic transthyretin amyloid assemblies 185
Reorganization of the outer layer of a model of the plasma membrane induced by a neuroprotective aminosterol 184
Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy 184
Probing the origin of the toxicity of oligomeric aggregates of α-synuclein with antibodies 184
Characterization of a novel Drosophila melanogaster acylphosphatase 183
FRET studies of various conformational states adopted by transthyretin 183
Squalamine and its derivatives modulate the aggregation of amyloid-β and α-synuclein and suppress the toxicity of their oligomers 183
Biophysical analysis of three novel profilin-1 variants associated with amyotrophic lateral sclerosis indicates a correlation between their aggregation propensity and the structural features of their globular state 182
Structural differences between toxic and nontoxic HypF-N oligomers 182
Extracellular chaperones prevent Aβ42-induced toxicity in rat brains 180
Nanoscale Discrimination between Toxic and Nontoxic Protein Misfolded Oligomers with Tip-Enhanced Raman Spectroscopy 180
Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers 179
Structure-toxicity relationship in intermediate fibrils from lα-Synuclein condensates 178
Quantitative Attribution of the Protective Effects of Aminosterols against Protein Aggregates to Their Chemical Structures and Ability to Modulate Biological Membranes 177
Squalamine and trodusquemine: two natural products for neurodegenerative diseases, from physical chemistry to the clinic 177
Aggregation of the acylphosphatase from S. solfataricus. The folded and partially unfolded states can be both precursors for amyloid formation. 175
Transthyretin suppresses the toxicity of oligomers formed by misfolded proteins in vitro 174
Protein misfolding, functional amyloid, and human disease 173
Exploring the mechanism of formation of native-like and precursor amyloid oligomers for the native acylphosphatase from Sulfolobus solfataricus. 173
Aβ oligomers dysregulate calcium homeostasis by mechanosensitive activation of AMPA and NMDA receptors. 173
Bis(indolyl)phenylmethane derivatives are effective small molecules for inhibition of amyloid fibril formation by hen lysozyme 173
A Brain-Permeable Aminosterol Regulates Cell Membranes to Mitigate the Toxicity of Diverse Pore-Forming Agents 172
Acceleration of the folding of acylphosphatase by stabilization of local secondary structure. 172
SERS Detection of Amyloid Oligomers on Metallorganic-Decorated Plasmonic Beads 171
Nature and significance of the interactions between amyloid fibrils and biological polyelectrolytes 169
Comparison of the folding processes of distantly related proteins. Importance of hydrophobic content in folding. 168
Chaperones suppress protein oligomer toxicity: Insight into the molecular mechanism of action 167
Totale 23.971
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Categoria #
all - tutte 108.602
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 108.602
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.067 0 0 103 34 47 58 64 83 56 74 233 315
2022/20233.781 324 618 194 406 299 683 511 160 361 29 118 78
2023/20241.446 61 181 213 75 99 254 59 264 24 87 71 58
2024/20259.293 274 968 541 1.413 2.815 1.131 219 440 458 234 404 396
2025/202611.569 1.231 1.519 948 767 1.228 481 1.293 638 814 813 348 1.489
2026/20271.277 367 357 553 0 0 0 0 0 0 0 0 0
Totale 40.309