CHITI, FABRIZIO
 Distribuzione geografica
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Continente #
NA - Nord America 16.817
EU - Europa 13.581
AS - Asia 7.199
SA - Sud America 896
AF - Africa 216
OC - Oceania 155
Continente sconosciuto - Info sul continente non disponibili 4
Totale 38.868
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Nazione #
US - Stati Uniti d'America 16.639
PL - Polonia 4.370
RU - Federazione Russa 3.242
IT - Italia 2.177
SG - Singapore 1.958
CN - Cina 1.783
HK - Hong Kong 1.037
IE - Irlanda 864
VN - Vietnam 791
BR - Brasile 716
SE - Svezia 710
KR - Corea 626
DE - Germania 550
FI - Finlandia 359
IN - India 334
UA - Ucraina 320
FR - Francia 305
GB - Regno Unito 246
AU - Australia 144
BD - Bangladesh 138
NL - Olanda 123
CH - Svizzera 108
ID - Indonesia 102
CA - Canada 91
JP - Giappone 78
ES - Italia 63
JO - Giordania 58
TR - Turchia 57
AR - Argentina 55
CI - Costa d'Avorio 40
MX - Messico 37
ZA - Sudafrica 36
IQ - Iraq 35
EC - Ecuador 32
NG - Nigeria 31
UZ - Uzbekistan 25
BE - Belgio 22
CL - Cile 22
CO - Colombia 21
MA - Marocco 20
PH - Filippine 20
PK - Pakistan 19
PY - Paraguay 17
AE - Emirati Arabi Uniti 16
EG - Egitto 16
LT - Lituania 16
SC - Seychelles 16
IR - Iran 14
RO - Romania 14
VE - Venezuela 14
KE - Kenya 13
AZ - Azerbaigian 12
IL - Israele 12
AT - Austria 11
BG - Bulgaria 11
BJ - Benin 11
MY - Malesia 11
NZ - Nuova Zelanda 11
SK - Slovacchia (Repubblica Slovacca) 11
SA - Arabia Saudita 10
JM - Giamaica 9
KZ - Kazakistan 9
PE - Perù 9
TH - Thailandia 9
TN - Tunisia 9
AL - Albania 8
CR - Costa Rica 8
HU - Ungheria 8
PT - Portogallo 8
DZ - Algeria 7
PA - Panama 7
TT - Trinidad e Tobago 7
CZ - Repubblica Ceca 6
DK - Danimarca 6
HN - Honduras 6
KG - Kirghizistan 6
NP - Nepal 6
BO - Bolivia 5
GE - Georgia 5
UY - Uruguay 5
AM - Armenia 4
BA - Bosnia-Erzegovina 4
CM - Camerun 4
DO - Repubblica Dominicana 4
ET - Etiopia 4
GR - Grecia 4
HR - Croazia 4
LB - Libano 4
TW - Taiwan 4
BH - Bahrain 3
GT - Guatemala 3
LU - Lussemburgo 3
MU - Mauritius 3
SY - Repubblica araba siriana 3
XK - ???statistics.table.value.countryCode.XK??? 3
GA - Gabon 2
KH - Cambogia 2
KW - Kuwait 2
MD - Moldavia 2
NI - Nicaragua 2
Totale 38.847
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Città #
Warsaw 4.356
Santa Clara 3.180
Ashburn 2.109
Fairfield 1.527
Singapore 1.395
Hong Kong 866
Dublin 863
Chandler 809
Woodbridge 718
Seattle 646
Seoul 607
Cambridge 577
Houston 565
Wilmington 546
Jacksonville 498
Milan 449
Hefei 428
San Jose 410
Beijing 353
Council Bluffs 267
Ann Arbor 255
Altamura 248
The Dalles 240
Florence 232
Ho Chi Minh City 230
Lawrence 219
Princeton 208
Los Angeles 204
Lauterbourg 185
Buffalo 182
Rome 174
Boardman 163
Boston 160
Moscow 147
Mumbai 140
Hanoi 137
Bremen 129
Melbourne 128
Helsinki 118
Munich 115
Dong Ket 106
New York 97
San Diego 89
Jakarta 86
Dallas 84
Pune 78
Kent 72
Naples 71
Shanghai 69
Medford 68
Bern 56
Paris 56
São Paulo 55
Turku 51
Clifton 48
Turin 45
Tokyo 44
Phoenix 43
Lappeenranta 41
Abidjan 40
Norwalk 38
Bologna 34
Izmir 34
Orem 33
London 32
Da Nang 31
Guangzhou 31
Redondo Beach 30
Chicago 29
Haiphong 29
Toronto 29
Abuja 28
Auburn Hills 27
Frankfurt am Main 27
Barcelona 26
Bengaluru 25
Tashkent 25
Figino 24
West Jordan 24
Brooklyn 22
Concord 21
Sabadell 21
Atlanta 20
Zurich 20
Andover 19
Miano 19
Montreal 19
Venice 19
Chennai 18
Hillsboro 18
Philadelphia 18
Verona 18
Bari 17
Brescia 17
Falls Church 17
Tianjin 17
Amsterdam 16
Basel 16
Brasília 16
Brussels 16
Totale 27.022
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Nome #
Protein misfolding, amyloid formation, and human disease: A summary of progress over the last decade 695
(1)H, (13)C and (15)N resonance assignments of human muscle acylphosphatase 560
A causative link between the structure of aberrant protein oligomers and their toxicity 480
Insight into the structure of amyloid fibrils from the analysis of globular proteins 365
Aggregation propensity of the human proteome 353
The Folding process of Human Profilin-1, a novel protein associated with familial amyotrophic lateral sclerosis 348
A computational approach for identifying the chemical factors involved in the glycosaminoglycans-mediated acceleration of amyloid fibril formation 347
Large proteins have a great tendency to aggregate but a low propensity to form amyloid fibrils 347
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 330
Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers 326
Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases 326
Cloning, expression and characterization of a new human LMW-PTP isoform originating by alternative splicing 325
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity 322
Quantification of the Relative Contributions of Loss-of function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies 313
Effect of molecular chaperones on aberrant protein oligomers in vitro: super- versus sub-stoichiometric chaperone concentrations 313
Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia 312
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 312
Soluble Oligomers Require a Ganglioside to Trigger Neuronal Calcium Overload 311
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 306
Patterns of cell death triggered in two different cell lines by HypF-N prefibrillar aggregates. 298
Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy 296
Toxic HypF-N oligomers selectively bind the plasma membrane to impair cell adhesion capability 281
The N-terminal helix controls the transition between the soluble and amyloid states of an FF domain. 277
Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions 272
Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicity 264
The contribution of acidic residues to the conformational stability of common-type acylphosphatase 262
Looking for residues involved in the muscle acylphosphatase catalytic mechanism and structural stabilization: role of Asn41, Ther42 and Thr46 259
Chaperones in Neurodegeneration 258
Thermodynamics and kinetics of folding of common type acylphosphatase 257
Molecular links between aberrant protein oligomers and neurodegeneration in Alzheimer’s disease 256
Multistep Inhibition of α‑Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine 252
Single particle tracking to study the binding of protein misfolded oligomer to membrane ganglioside GM1 249
Partial Failure of Proteostasis Systems Counteracting TDP-43 Aggregates in Neurodegenerative Diseases 247
The toxicity of misfolded protein oligomers is independent of their secondary structure 242
Backbone NMR assignments of HypF-N under conditions generating toxic and non-toxic oligomers 240
Capturing Aβ42 aggregation in the cell 229
Nanoscopic insights into the surface conformation of neurotoxic amyloid b oligomers 219
Isolation and characterization of soluble human full-length TDP-43 associated with neurodegeneration 217
Identification of Novel 1,3,5-Triphenylbenzene Derivative Compounds as Inhibitors of Hen Lysozyme Amyloid Fibril Formation 216
The induction of α-helical structure in partially unfolded HypF-N does not affect its aggregation propensity 216
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes 213
Amyloid Fibril Formation can Proceed from Different Conformations of a Partially Unfolded Protein 211
Assessing the role of aromatic residues in the amyloid aggregation of human muscle acylphosphatase 209
Chaperones as Suppressors of Protein Misfolded Oligomer Toxicity 208
Making biological membrane resistant to the toxicity of misfolded protein oligomers: a lesson from trodusquemine 207
Amyloid fibrils act as a reservoir of soluble oligomers, the main culprits in protein deposition diseases 207
Amyloid fibril formation and disaggregation of fragment 1-29 of apomyoglobin: insights into the effect of pH on protein fibrillogenesis 207
PROTEIN AGGREGATION STARTING FROM THE NATIVE GLOBULAR STATE 206
Amyloid formation from HypF-N under conditions in which the protein is initially in its native state 206
Direct Conversion of an Enzyme from Native-like to Amyloid-like Aggregates within Inclusion Bodies 203
Biophysical characterization of full-length TAR DNA-binding protein (TDP-43) phase separation. 202
Sphingosine 1-phosphate attenuates neuronal dysfunction induced by amyloid-β oligomers through endocytic internalization of NMDA receptors 202
Biological function in a non-native partially folded state of a protein. 202
A Complex Equilibrium among Partially Unfolded Conformations in Monomeric Transthyretin 201
Stability of an aggregation-prone partially folded state of human profilin-1 correlates with aggregation propensity 201
Amyloidogenesis in its biological environment: challenging a fundamental issue in protein misfolding diseases. 196
A comparison of the biochemical modifications caused by toxic and non-toxic protein oligomers in cells 196
Amyloid-β oligomer synaptotoxicity is mimicked by oligomers of the model protein HypF-N 196
Conversion of the Native N-Terminal Domain of TDP-43 into a Monomeric Alternative Fold with Lower Aggregation Propensity 195
Probing conformational changes of monomeric transthyretin with second derivative fluorescence 194
Studying the trafficking of labeled trodusquemine and its application as nerve marker for light-sheet and expansion microscopy 193
Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers 192
A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43 190
Characterizing intermolecular interactions that initiate native-like protein aggregation. 190
Quantitative Measurement of the Affinity of Toxic and Nontoxic Misfolded Protein Oligomers for Lipid Bilayers and of its Modulation by Lipid Composition and Trodusquemine 189
Evidence for a mechanism of amyloid formation involving molecular reorganisation within native-like precursor aggregates 188
An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature 187
Mutations of Profilin-1 Associated with Amyotrophic Lateral Sclerosis Promote Aggregation Due to Structural Changes of Its Native State 187
A model for the aggregation of the acylphosphatase from Sulfolobus solfataricus in its native-like state. 187
Glycosaminoglycans (GAGs) Suppress the Toxicity of HypF-N Prefibrillar Aggregates 185
Sequence and structural determinants of amyloid fibril formation 183
The polyphenol Oleuropein aglycone hinders the growth of toxic transthyretin amyloid assemblies 183
Probing the origin of the toxicity of oligomeric aggregates of α-synuclein with antibodies 182
Full-length TDP-43 and its C-terminal domain form filaments in vitro having non-amyloid properties 181
Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy 180
Reorganization of the outer layer of a model of the plasma membrane induced by a neuroprotective aminosterol 179
FRET studies of various conformational states adopted by transthyretin 179
Squalamine and its derivatives modulate the aggregation of amyloid-β and α-synuclein and suppress the toxicity of their oligomers 179
Biophysical analysis of three novel profilin-1 variants associated with amyotrophic lateral sclerosis indicates a correlation between their aggregation propensity and the structural features of their globular state 178
Structural differences between toxic and nontoxic HypF-N oligomers 178
Characterization of a novel Drosophila melanogaster acylphosphatase 176
Nanoscale Discrimination between Toxic and Nontoxic Protein Misfolded Oligomers with Tip-Enhanced Raman Spectroscopy 176
Extracellular chaperones prevent Aβ42-induced toxicity in rat brains 175
Structure-toxicity relationship in intermediate fibrils from lα-Synuclein condensates 173
C-terminal region contributes to muscle acylphosphatase three-dimensional structure stabilisation 173
Exploring the mechanism of formation of native-like and precursor amyloid oligomers for the native acylphosphatase from Sulfolobus solfataricus. 173
Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers 173
Squalamine and trodusquemine: two natural products for neurodegenerative diseases, from physical chemistry to the clinic 172
Aggregation of the acylphosphatase from S. solfataricus. The folded and partially unfolded states can be both precursors for amyloid formation. 172
Quantitative Attribution of the Protective Effects of Aminosterols against Protein Aggregates to Their Chemical Structures and Ability to Modulate Biological Membranes 171
Bis(indolyl)phenylmethane derivatives are effective small molecules for inhibition of amyloid fibril formation by hen lysozyme 171
Aβ oligomers dysregulate calcium homeostasis by mechanosensitive activation of AMPA and NMDA receptors. 170
Transthyretin suppresses the toxicity of oligomers formed by misfolded proteins in vitro 169
A Brain-Permeable Aminosterol Regulates Cell Membranes to Mitigate the Toxicity of Diverse Pore-Forming Agents 168
Acceleration of the folding of acylphosphatase by stabilization of local secondary structure. 168
SERS Detection of Amyloid Oligomers on Metallorganic-Decorated Plasmonic Beads 166
Nature and significance of the interactions between amyloid fibrils and biological polyelectrolytes 165
Differential interactome and innate immune response activation of two structurally distinct misfolded protein oligomers 165
Comparison of the folding processes of distantly related proteins. Importance of hydrophobic content in folding. 163
Protein misfolding, functional amyloid, and human disease 163
Totale 23.452
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Categoria #
all - tutte 103.046
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 103.046
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.302 78 157 103 34 47 58 64 83 56 74 233 315
2022/20233.781 324 618 194 406 299 683 511 160 361 29 118 78
2023/20241.446 61 181 213 75 99 254 59 264 24 87 71 58
2024/20259.293 274 968 541 1.413 2.815 1.131 219 440 458 234 404 396
2025/202611.603 1.231 1.519 948 767 1.228 481 1.293 638 814 823 356 1.505
2026/2027104 104 0 0 0 0 0 0 0 0 0 0 0
Totale 39.170