SUPURAN, CLAUDIU TRANDAFIR
SUPURAN, CLAUDIU TRANDAFIR
Neuroscienze, Area del Farmaco e Salute del Bambino (NEUROFARBA)
"a Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII
2020 Bua S.; Lomelino C.; Murray A.B.; Osman S.M.; Alothman Z.A.; Bozdag M.; Abdel-Aziz H.A.; Eldehna W.M.; McKenna R.; Nocentini A.; Supuran C.T.
"Seriously Sweet": Acesulfame K Exhibits Selective Inhibition Using Alternative Binding Modes in Carbonic Anhydrase Isoforms
2018 Murray, Akilah B; Lomelino, Carrie L; Supuran, Claudiu T; Mckenna, Robert
(Hetero)aryl substituted thiazol-2,4-yl scaffold as human carbonic anhydrase I, II, VII and XIV activators
2019 Rami, Marouan; Winum, Jean-Yves; Supuran, Claudiu T; Melnyk, Patricia; Yous, Saïd
(In)organic anions as carbonic anhydrase inhibitors.
2012 G. D. Simone;C. T. Supuran
(R)-/(S)-10-camphorsulfonyl-substituted aromatic/heterocyclic sulfonamides selectively inhibit mitochondrial over cytosolic carbonic anhydrases.
2011 A. Maresca;C. T. Supuran
1,2,3-Benzoxathiazine-2,2-dioxides - effective inhibitors of human carbonic anhydrases
2023 Ivanova, Jekaterina; Abdoli, Morteza; Nocentini, Alessio; Žalubovskis, Raivis; Supuran, Claudiu T
1,2,4-Triazole-based anticonvulsant agents with additional ROS scavenging activity are effective in a model of pharmacoresistant epilepsy
2020 Kaproń, Barbara; Czarnomysy, Robert; Wysokiński, Mariusz; Andrys, Rudolf; Musilek, Kamil; Angeli, Andrea; Supuran, Claudiu T; Plech, Tomasz
1,2,4-Trisubstituted imidazolinones with dual carbonic anhydrase and p38 mitogen-activated protein kinase inhibitory activity
2019 Georgey, Hanan H; Manhi, Fatma M; Mahmoud, Walaa R; Mohamed, Nehad A; Berrino, Emanuela; Supuran, Claudiu T
1,2-Benzisothiazole Derivatives Bearing 4-, 5-, or 6-Alkyl/arylcarboxamide Moieties Inhibit Carbonic Anhydrase Isoform IX (CAIX) and Cell Proliferation under Hypoxic Conditions
2016 Coviello, Vito; Marchi, Beatrice; Sartini, Stefania; Quattrini, Luca; Marini, Anna Maria; Simorini, Francesca; Taliani, Sabrina; Salerno, Silvia; Orlandi, Paola; Fioravanti, Anna; Desidero, Teresa Di; Vullo, Daniela; Da Settimo, Federico; Supuran, Claudiu T; Bocci, Guido; La Motta, Concettina
1,3,4-thiadiazole derivatives. Part 9. Synthesis and biological activity of metal complexes of 5-(2-aminoethyl)-2-amino-1,3,4-thiadiazole.
1996 M. Barboiu;M. Cimpoesu;C. Guran;C. T. Supuran
1,3-Dipolar Cycloaddition, HPLC Enantioseparation, and Docking Studies of Saccharin/Isoxazole and Saccharin/Isoxazoline Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors
2020 D'Ascenzio M.; Secci D.; Carradori S.; Zara S.; Guglielmi P.; Cirilli R.; Pierini M.; Poli G.; Tuccinardi T.; Angeli A.; Supuran C.T.
1,3-Oxazole-based selective picomolar inhibitors of cytosolic human carbonic anhydrase II alleviate ocular hypertension in rabbits: Potency is supported by X-ray crystallography of two leads
2017 Ferraroni, Marta; Lucarini, Laura; Masini, Emanuela; Korsakov, Mikhail; Scozzafava, Andrea; Supuran, Claudiu T.*; Krasavin, Mikhail
1,5-Benzodiazepines as a platform for the design of carbonic anhydrase inhibitors
2022 Ismail C.; Nocentini A.; Supuran C.T.; Winum J.-Y.; Gharbi R.
2-((1H-Benzo[d]imidazol-2-yl)amino)benzo[d]thiazole-6-sulphonamides: a class of carbonic anhydrase II and VII-selective inhibitors
2023 Abdoli, Morteza; Supuran, Claudiu T; Žalubovskis, Raivis
2-(2-Hydroxyethyl)piperazine derivatives as potent human carbonic anhydrase inhibitors: Synthesis, enzyme inhibition, computational studies and antiglaucoma activity
2022 Chiaramonte N.; Angeli A.; Sgambellone S.; Bonardi A.; Nocentini A.; Bartolucci G.; Braconi L.; Dei S.; Lucarini L.; Teodori E.; Gratteri P.; Wunsch B.; Supuran C.T.; Romanelli M.N.
2-Aminobenzoxazole-appended coumarins as potent and selective inhibitors of tumour-associated carbonic anhydrases
2022 Fuentes-Aguilar A.; Merino-Montiel P.; Montiel-Smith S.; Meza-Reyes S.; Vega-Baez J.L.; Puerta A.; Fernandes M.X.; Padron J.M.; Petreni A.; Nocentini A.; Supuran C.T.; Lopez O.; Fernandez-Bolanos J.G.
2-Benzylpiperazine: a new scaffold for potent human Carbonic Anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents.
2018 Niccolò Chiaramonte, Silvia Bua, Marta Ferraroni, Alessio Nocentini, Alessandro Bonardi, Gian Luca Bartolucci, Maria Concetta Durante, Laura Lucarini, Donata Chiapponi, Silvia Dei, Dina Manetti, Elisabetta Teodori, Paola Gratteri, Emanuela Masini, Claudiu T. Supuran, Maria Novella Romanelli
2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site
2020 Bozdag M.; Supuran C.T.; Esposito D.; Angeli A.; Carta F.; Monti S.M.; De Simone G.; Alterio V.
2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity.
2006 M. P. Leese;B. Leblond;A. Smith;S. P. Newman;A. D. Fiore;G. D. Simone;C. T. Supuran;A. Purohit;M. J. Reed;B. V. L
3-Aminobenzenesulfonamides incorporating acylthiourea moieties selectively inhibit the tumor-associated carbonic anhydrase isoform IX over the off-target isoforms I, II and IV
2019 Fattah, Tanzeela Abdul; Bua, Silvia; Saeed, Aamer; Shabir, Ghulam; Supuran, Claudiu T