FANI, GIULIA

FANI, GIULIA  

Scienze Biomediche, Sperimentali e Cliniche 'Mario Serio'  

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Aβ oligomers dysregulate calcium homeostasis by mechanosensitive activation of AMPA and NMDA receptors. 2021 Giulia Fani, Benedetta Mannini, Giulia Vecchi, Roberta Cascella, Cristina Cecchi, Christopher M. Dobson, Michele Vendruscolo, Fabrizio Chiti
Differential interactome and innate immune response activation of two structurally distinct misfolded protein oligomers 2019 Mannini, Benedetta; Vecchi, Giulia; Labrador-Garrido, Adahir; Fabre, Bertrand; Fani, Giulia; Munoz Franco, Jaime; Lilley, Kathryn S; Pozo, David; Vendruscolo, Michele; Chiti, Fabrizio; Dobson, Christopher M; Roodveldt, Cintia
Full-length TDP-43 and its C-terminal domain form filaments in vitro having non-amyloid properties 2021 Capitini, Claudia; Fani, Giulia; Vivoli Vega, Mirella; Penco, Amanda; Canale, Claudio; Cabrita, Lisa D; Calamai, Martino; Christodoulou, John; Relini, Annalisa; Chiti, Fabrizio
IDENTIFICATION OF MEMBRANE CA2+ CHANNELS ACTIVATED BY PROTEIN MISFOLDED OLIGOMERS AND THEIR ACTIVATION MECHANISM 2021 Giulia Fani
Isolation and characterization of soluble human full-length TDP-43 associated with neurodegeneration 2019 Vivoli Vega, Mirella; Nigro, Alessia; Luti, Simone; Capitini, Claudia; Fani, Giulia; Gonnelli, Leonardo; Boscaro, Francesca; Chiti, Fabrizio
Mechanosensitivity of N-methyl-D-aspartate receptors (NMDAR) is the key through which amyloid beta oligomers activate them 2022 Fani, Giulia; Chiti, Fabrizio
Misfolded protein oligomers induce an increase of intracellular Ca2+ causing an escalation of reactive oxidative species 2022 Giulia Fani, Chiara Ester La Torre, Roberta Cascella, Cristina Cecchi, Michele Vendruscolo, Fabrizio Chiti
Partial Failure of Proteostasis Systems Counteracting TDP-43 Aggregates in Neurodegenerative Diseases 2019 Cascella R, Fani G, Bigi A, Chiti F, Cecchi C.
Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy 2017 Cascella, Roberta; Fani, Giulia; Capitini, Claudia; Rusmini, Paola; Poletti, Angelo; Cecchi, Cristina; Chiti, Fabrizio*
Soluble Prion peptide 107–120 protects neuroblastoma SH-SY5Y cells against oligomers associated with Alzheimer’s disease 2020 Elham Rezvani Boroujeni, Seyed Masoud Hosseini, Giulia Fani, Cristina Cecchi, Fabrizio Chiti
Sphingosine 1-phosphate attenuates neuronal dysfunction induced by amyloid-β oligomers through endocytic internalization of NMDA receptors 2022 Bigi A, Cascella R, Fani G, Bernacchioni C, Cencetti F, Bruni P, Chiti F, Donati C, Cecchi C.