The neurobiological changes underlying depression resistant to treatments remain poorly understood, and failure to respond to selective serotonin reuptake inhibitors (SSRIs) may result from abnormalities of neurotransmitter systems that excite serotonergic neurons, such as histamine.
Brain histamine is crucial for selective serotonin reuptake inhibitors behavioral and neurochemical effects / Leonardo Munari, Gustavo Provensi, Maria Beatrice Passani, Nicoletta Galeotti, Tommaso Cassano, Fernando Benetti, Renato Corradetti, Patrizio Blandina. - In: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. - ISSN 1461-1457. - STAMPA. - 18:(2015), pp. 1-10. [10.1093/ijnp/pyv045]
Brain histamine is crucial for selective serotonin reuptake inhibitors behavioral and neurochemical effects
Leonardo Munari;Gustavo Provensi;Maria Beatrice Passani;Nicoletta Galeotti;Fernando Benetti;Renato Corradetti;Patrizio Blandina
2015
Abstract
The neurobiological changes underlying depression resistant to treatments remain poorly understood, and failure to respond to selective serotonin reuptake inhibitors (SSRIs) may result from abnormalities of neurotransmitter systems that excite serotonergic neurons, such as histamine.
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