1-(Organooxy)alk-1-ynes and 1-(Heterooxy)alk-1-ynes (Update 2015, Vol. 24)

This chapter is an update to the earlier Science of Synthesis contribution describing methods for the synthesis of 1-(organooxy)alk- 1-ynes and 1-(heterooxy)alk- 1-ynes. The original contribution describes the synthesis of six subgroups; alk-1- ynyl N,N-dialkylcarbamates, carboxylates, ethers, sulfonates, and dialkyl phosphonates as well as 1-siloxyalk- 1-ynes. However, during the period covered in this update (2005 – 2014), new contributions have only been made in the field of alk-1- ynyl ethers and 1-siloxyalk- 1-ynes. These methodologies, primarily methods centering on elimination reactions, are covered in this chapter along with a short description of the applications of the two compound groups.