Learning objectives • To understand the pathogenesis of tissue fibrosis in systemic sclerosis (SSc or scleroderma) and the interactions between the vascular and immune systems and fibroblasts. • To understand the role of fibroblasts and their transition to profibrotic myofibroblasts. • To become familiar with the profibrotic factors and mechanisms involved in SSc.
Synthesis: fibrosis in systemic sclerosis / Mirko Manetti; Alina Soare. - STAMPA. - (2019), pp. 84-97.
Synthesis: fibrosis in systemic sclerosis
Mirko Manetti
;
2019
Abstract
Learning objectives • To understand the pathogenesis of tissue fibrosis in systemic sclerosis (SSc or scleroderma) and the interactions between the vascular and immune systems and fibroblasts. • To understand the role of fibroblasts and their transition to profibrotic myofibroblasts. • To become familiar with the profibrotic factors and mechanisms involved in SSc.
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