The effects of transcutaneous electrical nerve stimulation on plasma and cerebrospinal fluid (CSF) levels of beta-Endorphin (beta-EP) were studied in 6 groups of pain-free patients. Different modes of TENS were applied for 20 minutes. Regardless of mode and/or frequency of the stimulation plasma and/or CSF beta-EP levels were significantly increased. Plasma and CSF responses were not correlated suggesting that TENS activates different opiatergic pathways at central and peripheral level.
Central and peripheral beta-endorphin response to transcutaneous electrical nerve stimulation / Facchinetti, F.*; Sforza, G.; Amidei, M.; Cozza, C.; Petraglia, F.; Montanari, C.; Genazzani, A.R.. - ELETTRONICO. - (1986), pp. 555-558.
Central and peripheral beta-endorphin response to transcutaneous electrical nerve stimulation
Facchinetti, F.;Petraglia, F.;
1986
Abstract
The effects of transcutaneous electrical nerve stimulation on plasma and cerebrospinal fluid (CSF) levels of beta-Endorphin (beta-EP) were studied in 6 groups of pain-free patients. Different modes of TENS were applied for 20 minutes. Regardless of mode and/or frequency of the stimulation plasma and/or CSF beta-EP levels were significantly increased. Plasma and CSF responses were not correlated suggesting that TENS activates different opiatergic pathways at central and peripheral level.
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