It is well known that venules equipped with valves play a critical role in regulating blood flow. Essentially they are peristaltic pumps that increase the efficiency of venous blood return to the heart, thanks to the presence of valves preventing backflow. Inspired by two recent papers, we have modeled the venule as a vessel with valves placed at its ends and walls animated by radial oscillations that are independent of heart pulsation and respiratory rhythm. Differently from the previous papers, the present model takes into account the valves inertia allowing, for progressive closing/opening stages. The numerical simulations produce a pressure pulse and a velocity profile which agree almost perfectly with the experimental data of Dongaonkar et al., eliminating the discrepancies found in Farina et al., arising from the hypothesis that valves act instantaneously

Blood flow in venules: A mathematical model including valves inertia / Angiolo Farina, Antonio Fasano, Matteo Cardini, Alberto Caggiati. - In: VEINS AND LYMPHATICS. - ISSN 2279-7483. - STAMPA. - 8:(2019), pp. 59-62.

Blood flow in venules: A mathematical model including valves inertia

Angiolo Farina
;
Antonio Fasano;
2019

Abstract

It is well known that venules equipped with valves play a critical role in regulating blood flow. Essentially they are peristaltic pumps that increase the efficiency of venous blood return to the heart, thanks to the presence of valves preventing backflow. Inspired by two recent papers, we have modeled the venule as a vessel with valves placed at its ends and walls animated by radial oscillations that are independent of heart pulsation and respiratory rhythm. Differently from the previous papers, the present model takes into account the valves inertia allowing, for progressive closing/opening stages. The numerical simulations produce a pressure pulse and a velocity profile which agree almost perfectly with the experimental data of Dongaonkar et al., eliminating the discrepancies found in Farina et al., arising from the hypothesis that valves act instantaneously
2019
8
59
62
Angiolo Farina, Antonio Fasano, Matteo Cardini, Alberto Caggiati
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1191907
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