Primary immune deficiencies are a heterogeneous group of inherited disorders generally caused by specific gene mutations affecting the immune system and leading to various clinical manifestations, including severe infections, autoimmunity, and malignancies. In this chapter, general considerations on primary immune deficiency as well as the various circumstances in which a primary immune deficiency is evoked are described. This chapter serves as a roadmap to understand the layout of this book and it mirrors the clinical approach taken by immunologists.
Common presentations and diagnostic approaches / Rezaei, Nima; de Vries, Esther; Gambineri, Eleonora; Meyts, Isabelle; Haddad, Elie. - STAMPA. - (2020), pp. 3-59. [10.1016/b978-0-12-816768-7.00001-6]
Common presentations and diagnostic approaches
Gambineri, Eleonora;
2020
Abstract
Primary immune deficiencies are a heterogeneous group of inherited disorders generally caused by specific gene mutations affecting the immune system and leading to various clinical manifestations, including severe infections, autoimmunity, and malignancies. In this chapter, general considerations on primary immune deficiency as well as the various circumstances in which a primary immune deficiency is evoked are described. This chapter serves as a roadmap to understand the layout of this book and it mirrors the clinical approach taken by immunologists.
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