The breakdown of the immunological tolerance to myelin components is probably crucial in the pathogenesis of multiple sclerosis (MS). Even if the target autoantigen is yet unknown, myelin basic protein (MBP) has been studied in greatest detail.
The affinity spectrum of myelin basic protein reactive T cells / B. Mazzanti; E. Traggiai; B. Hemmer; R. Martin; L. Massacesi; M. Vergelli. - STAMPA. - (1999), pp. 3-10. [10.1007/978-88-470-2269-0_2]
The affinity spectrum of myelin basic protein reactive T cells.
MASSACESI, LUCA;
1999
Abstract
The breakdown of the immunological tolerance to myelin components is probably crucial in the pathogenesis of multiple sclerosis (MS). Even if the target autoantigen is yet unknown, myelin basic protein (MBP) has been studied in greatest detail.
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