Reaction of 6-acetyl-7-(2-dimethylaminovinyl)pyrazolo[1,5-a]pyrimidine 1 with 1,3- and 1,4-bisnucleophiles has been investigated; obtainment of new polycyclic heterocyclic derivatives is reported. A convenient procedure leading to new pyrazolo[1,5-a]quinazolines is described; a modest bioactivity of these compounds against two human tumor cell lines was also ascertained.

On the reactivity of 6-acetyl-7-(2-dimethylaminovinyl)pyrazolo[1,5-a]pyrimidines with 1,3- and 1,4-bisnucleophiles / S. Chimichi; M. Boccalini; S. Selleri; C. Costagli; G. Guerrini; G. Viola. - In: ORGANIC & BIOMOLECULAR CHEMISTRY. - ISSN 1477-0520. - STAMPA. - 6:(2008), pp. 739-744. [10.1039/b717835b]

On the reactivity of 6-acetyl-7-(2-dimethylaminovinyl)pyrazolo[1,5-a]pyrimidines with 1,3- and 1,4-bisnucleophiles

CHIMICHI, STEFANO;BOCCALINI, MARCO;SELLERI, SILVIA;GUERRINI, GABRIELLA;
2008

Abstract

Reaction of 6-acetyl-7-(2-dimethylaminovinyl)pyrazolo[1,5-a]pyrimidine 1 with 1,3- and 1,4-bisnucleophiles has been investigated; obtainment of new polycyclic heterocyclic derivatives is reported. A convenient procedure leading to new pyrazolo[1,5-a]quinazolines is described; a modest bioactivity of these compounds against two human tumor cell lines was also ascertained.
2008
6
739
744
S. Chimichi; M. Boccalini; S. Selleri; C. Costagli; G. Guerrini; G. Viola
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/344491
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