Bone-grafting techniques either with autografts or allografts still represent a challenge for reconstructive surgery. Allografts and autografts are the current strategies for filling bone defects and subsequent repair but each have drawbacks. Synthetic bone-graft substitutes, developed in an effort to overcome the inherent limitations of autograft and allograft, represent an alternative strategy. Synthetic bone graft substitutes have the goal of mimicking the physical and mechanical nature of native tissue and to promote osteoconduction for bone regeneration. In addition these substitutes are capable to release drugs or growth factors in a temporally and spatially manner. Some biomaterials are employed to design biomimetic scaffold such as natural and synthetic polymers, ceramics, metallics and composites. The purpose of this paper is to provide an overview of the main biomaterials used for bone reconstruction.

New biomaterials for bone regeneration / F. Matassi; L. Nistri; D. Chicon Paez; M. Innocenti. - In: CLINICAL CASES IN MINERAL AND BONE METABOLISM. - ISSN 1724-8914. - ELETTRONICO. - (2011), pp. 21-24.

New biomaterials for bone regeneration

MATASSI, FABRIZIO;NISTRI, LORENZO;CHICON PAEZ, DIANA;INNOCENTI, MASSIMO
2011

Abstract

Bone-grafting techniques either with autografts or allografts still represent a challenge for reconstructive surgery. Allografts and autografts are the current strategies for filling bone defects and subsequent repair but each have drawbacks. Synthetic bone-graft substitutes, developed in an effort to overcome the inherent limitations of autograft and allograft, represent an alternative strategy. Synthetic bone graft substitutes have the goal of mimicking the physical and mechanical nature of native tissue and to promote osteoconduction for bone regeneration. In addition these substitutes are capable to release drugs or growth factors in a temporally and spatially manner. Some biomaterials are employed to design biomimetic scaffold such as natural and synthetic polymers, ceramics, metallics and composites. The purpose of this paper is to provide an overview of the main biomaterials used for bone reconstruction.
2011
21
24
F. Matassi; L. Nistri; D. Chicon Paez; M. Innocenti
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/657185
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