MANNINI, BENEDETTA
 Distribuzione geografica
Continente #
NA - Nord America 2.008
EU - Europa 1.704
AS - Asia 461
OC - Oceania 25
SA - Sud America 14
AF - Africa 5
Totale 4.217
Nazione #
US - Stati Uniti d'America 1.998
PL - Polonia 756
RU - Federazione Russa 489
SG - Singapore 154
IT - Italia 141
HK - Hong Kong 139
IE - Irlanda 108
SE - Svezia 88
IN - India 51
CN - Cina 41
DE - Germania 40
FI - Finlandia 27
AU - Australia 25
ID - Indonesia 21
VN - Vietnam 17
GB - Regno Unito 16
KR - Corea 12
BR - Brasile 11
ES - Italia 10
CH - Svizzera 9
JO - Giordania 9
TR - Turchia 8
CA - Canada 6
FR - Francia 5
CI - Costa d'Avorio 3
UA - Ucraina 3
AE - Emirati Arabi Uniti 2
AT - Austria 2
MX - Messico 2
NL - Olanda 2
RO - Romania 2
AL - Albania 1
AR - Argentina 1
BE - Belgio 1
BG - Bulgaria 1
BH - Bahrain 1
CM - Camerun 1
CZ - Repubblica Ceca 1
GT - Guatemala 1
HU - Ungheria 1
IQ - Iraq 1
IR - Iran 1
JP - Giappone 1
KG - Kirghizistan 1
LB - Libano 1
MA - Marocco 1
PA - Panama 1
PE - Perù 1
PT - Portogallo 1
PY - Paraguay 1
TW - Taiwan 1
Totale 4.217
Città #
Santa Clara 756
Warsaw 756
Fairfield 176
Chandler 126
Hong Kong 122
Ashburn 115
Dublin 108
Seattle 84
Singapore 80
Woodbridge 78
Wilmington 69
Houston 68
Cambridge 66
Florence 42
Lawrence 41
Altamura 36
Moscow 28
Mumbai 27
Princeton 26
Melbourne 24
Pune 23
Ann Arbor 22
Bremen 22
Jakarta 21
Boston 18
Boardman 15
San Diego 13
Beijing 12
Dong Ket 12
Helsinki 12
Shanghai 12
Medford 10
Bern 9
Seongnam 9
Barcelona 8
Norwalk 8
Cagliari 7
Falls Church 7
Jacksonville 7
Los Angeles 7
Milan 7
Hillsboro 5
Izmir 5
Kent 4
London 4
Phoenix 4
Serra 4
Abidjan 3
Carmignano 3
Council Bluffs 3
Dallas 3
Orenburg 3
Ottawa 3
Redwood City 3
Toronto 3
Turin 3
Andover 2
Bucharest 2
Buffalo 2
Guadalupe 2
Kensington 2
Manchester 2
Mozzo 2
Newham 2
Nuremberg 2
Paris 2
Ponte Buggianese 2
Rome 2
Romola 2
San Mateo 2
Savona 2
Seoul 2
West Jordan 2
Yubileyny 2
Anghiari 1
Araguari 1
Barretos 1
Bethesda 1
Bishkek 1
Brno 1
Bromma 1
Campi Bisenzio 1
Carmo do Cajuru 1
Casablanca 1
Chicago 1
Chiswick 1
Dearborn 1
Dezhou 1
Duque de Caxias 1
Erbil 1
Esslingen am Neckar 1
Fuyang 1
Guatemala City 1
Hangzhou 1
Hefei 1
Itajubá 1
Jinan 1
Kilburn 1
Konya 1
Kunming 1
Totale 3.204
Nome #
A causative link between the structure of aberrant protein oligomers and their toxicity 295
Large proteins have a great tendency to aggregate but a low propensity to form amyloid fibrils 281
Effect of molecular chaperones on aberrant protein oligomers in vitro: super- versus sub-stoichiometric chaperone concentrations 249
Early-forming aberrant aggregates in protein deposition diseases: structural characteristics, interaction with molecular chaperones, ability to trigger inflammation 232
Toxic HypF-N oligomers selectively bind the plasma membrane to impair cell adhesion capability 231
Multistep Inhibition of α‑Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine 178
Chaperones as Suppressors of Protein Misfolded Oligomer Toxicity 155
The induction of α-helical structure in partially unfolded HypF-N does not affect its aggregation propensity 147
Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers 143
A comparison of the biochemical modifications caused by toxic and non-toxic protein oligomers in cells 135
Amyloid-β oligomer synaptotoxicity is mimicked by oligomers of the model protein HypF-N 134
Glycosaminoglycans (GAGs) Suppress the Toxicity of HypF-N Prefibrillar Aggregates 133
SERS Detection of Amyloid Oligomers on Metallorganic-Decorated Plasmonic Beads 129
Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism 127
Salt anions promote the conversion of HypF-N into amyloid-like oligomers and modulate the structure of the oligomers and the monomeric precursor state. 119
Bis(indolyl)phenylmethane derivatives are effective small molecules for inhibition of amyloid fibril formation by hen lysozyme 119
Differential interactome and innate immune response activation of two structurally distinct misfolded protein oligomers 116
Squalamine and its derivatives modulate the aggregation of amyloid-β and α-synuclein and suppress the toxicity of their oligomers 104
Chaperones suppress protein oligomer toxicity: Insight into the molecular mechanism of action 95
Toxicity of Protein Oligomers Is Rationalized by a Function Combining Size and Surface Hydrophobicity 93
Aβ oligomers dysregulate calcium homeostasis by mechanosensitive activation of AMPA and NMDA receptors. 92
Rationally designed antibodies as research tools to study the structure–toxicity relationship of amyloid-β oligomers 85
Chaperones suppress the toxicity of aberrant protein aggregates. Molecular insight into the mechanism of action 85
Small-molecule sequestration of amyloid-beta. as a drug discovery strategy for Alzheimer's disease 82
Distinct responses of human peripheral blood cells to different misfolded protein oligomers 59
Exogenous misfolded protein oligomers can cross the intestinal barrier and cause a disease phenotype in C. elegans 55
A Relationship between the Structures and Neurotoxic Effects of Aβ Oligomers Stabilized by Different Metal Ions 46
A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers 46
Delivery of Native Proteins into C. Elegans Using a Transduction Protocol Based on Lipid Vesicles 45
A rationally designed bicyclic peptide remodels Aβ42 aggregation in vitro and reduces its toxicity in a worm model of Alzheimer’s disease 42
Proteome-wide observation of the phenomenon of life on the edge of solubility 39
The Pathological G51D Mutation in Alpha-Synuclein Oligomers Confers Distinct Structural Attributes and Cellular Toxicity 39
Stabilization and Characterization of Cytotoxic Aβ40 Oligomers Isolated from an Aggregation Reaction in the Presence of Zinc Ions 38
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's disease 38
Therapeutic strategies to reduce the toxicity of misfolded protein oligomers 36
Small Molecule Inhibitors for Precise Inhibition of Alpha-Synuclein Oligomer Generation in Parkinson’s Disease (S32.002) 36
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers 36
Two human metabolites rescue a C. elegans model of Alzheimer’s disease via a cytosolic unfolded protein response 35
Single molecule secondary structure determination of proteins through infrared absorption nanospectroscopy 35
Surface-Catalyzed Secondary Nucleation Dominates the Generation of Toxic IAPP Aggregates 34
Structure-Based Discovery of Small-Molecule Inhibitors of the Autocatalytic Proliferation of α-Synuclein Aggregates 31
Preparation and Characterization of Zn(II)-Stabilized Aβ42 Oligomers 26
Targeting Protein Aggregation in ALS 24
Totale 4.299
Categoria #
all - tutte 11.772
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 11.772


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020140 0 0 0 0 0 0 0 0 54 32 47 7
2020/2021386 32 39 4 65 17 50 18 24 41 51 19 26
2021/2022162 1 25 16 5 3 7 8 14 10 9 18 46
2022/2023562 37 109 36 52 44 104 66 32 50 3 16 13
2023/2024274 9 28 27 9 9 42 10 50 4 61 14 11
2024/20251.760 49 215 87 266 662 259 41 64 117 0 0 0
Totale 4.299