SGAMBELLONE, SILVIA
SGAMBELLONE, SILVIA
Neuroscienze, Psicologia, Area del Farmaco e Salute del Bambino (NEUROFARBA)
2-(2-Hydroxyethyl)piperazine derivatives as potent human carbonic anhydrase inhibitors: Synthesis, enzyme inhibition, computational studies and antiglaucoma activity
2022 Chiaramonte N.; Angeli A.; Sgambellone S.; Bonardi A.; Nocentini A.; Bartolucci G.; Braconi L.; Dei S.; Lucarini L.; Teodori E.; Gratteri P.; Wunsch B.; Supuran C.T.; Romanelli M.N.
Adenosine A3 Receptor (A3AR) Agonist for the Treatment of Bleomycin-Induced Lung Fibrosis in Mice
2022 Sgambellone, Silvia; Marri, Silvia; Catarinicchia, Stefano; Pini, Alessandro; Tosh, Dilip K.; Jacobson, Kenneth A.; Masini, Emanuela; Salvemini, Daniela; Lucarini, Laura
CNS-Sparing Histamine H3 Receptor Antagonist as a Candidate to Prevent the Diabetes-Associated Gastrointestinal Symptoms
2022 Rosa, Arianna Carolina; Nardini, Patrizia; Sgambellone, Silvia; Gurrieri, Maura; Spampinato, Simona Federica; Dell'Accio, Alfonso; Chazot, Paul L; Obara, Ilona; Liu, Wai L; Pini, Alessandro
D-Tagatose Feeding Reduces the Risk of Sugar-Induced Exacerbation of Myocardial I/R Injury When Compared to Its Isomer Fructose
2021 Mariaconcetta Durante, Silvia Sgambellone, Laura Lucarini, Paola Failli, Annunziatina Laurino, Debora Collotta, Gustavo Provensi, Emanuela Masini, Massimo Collino
Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy
2018 Nocentini, Alessio; Ceruso, Mariangela; Bua, Silvia; Lomelino, Carrie L.; Andring, Jacob T.; McKenna, Robert; Lanzi, Cecilia; Sgambellone, Silvia; Pecori, Riccardo; Matucci, Rosanna; Filippi, Luca; Gratteri, Paola; Carta, Fabrizio; Masini, Emanuela; Selleri, Silvia*; Supuran, Claudiu T.
Effects of new nsaid-cai hybrid compounds in inflammation and lung fibrosis
2020 Lucarini L.; Durante M.; Sgambellone S.; Lanzi C.; Bigagli E.; Akgul O.; Masini E.; Supuran C.T.; Carta F.
Effects of PARP-1 deficiency and histamine H4receptor inhibition in an inflammatory model of lung fibrosis in mice
2019 Durante M.; Sgambellone S.; Lanzi C.; Nardini P.; Pini A.; Moroni F.; Masini E.; Lucarini L.
Histamine H3 receptor (H3R) antagonist-Nitric Oxide (NO) donor hybrid compounds as a new therapeutic strategy for the treatment of glaucoma and retinal neuroprotection
2023 Sgambellone Silvia
Identification of Bivalent Ligands with Melatonin Receptor Agonist and Fatty Acid Amide Hydrolase (FAAH) Inhibitory Activity That Exhibit Ocular Hypotensive Effect in the Rabbit
2018 Spadoni, Gilberto; Bedini, Annalida; Furiassi, Lucia; Mari, Michele; Mor, Marco; Scalvini, Laura; Lodola, Alessio; Ghidini, Andrea; Lucini, Valeria; Dugnani, Silvana; Scaglione, Francesco; Piomelli, Daniele; Jung, Kwang-Mook; Supuran, Claudiu T; Lucarini, Laura; Durante, Mariaconcetta; Sgambellone, Silvia; Masini, Emanuela; Rivara, Silvia
NCX 470 Exerts Retinal Cell Protection and Enhances Ophthalmic Artery Blood Flow After Ischemia/Reperfusion Injury of Optic Nerve Head and Retina
2023 Sgambellone, Silvia; Marri, Silvia; Villano, Serafina; Masini, Emanuela; Provensi, Gustavo; Bastia, Elena; Galli, Corinna; Brambilla, Stefania; Impagnatiello, Francesco; Lucarini, Laura
NCX 470 Restores Ocular Hemodynamics and Retinal Cell Physiology After ET-1-Induced Ischemia/Reperfusion Injury of Optic Nerve and Retina in Rabbits
2022 Elena Bastia; Silvia Sgambellone; Laura Lucarini; Gustavo Provensi; Stefania Brambilla; Corinna Galli; Nicoletta Almirante; Francesco Impagnatiello
Novel Carbonic Anhydrase Inhibitors with Dual-Tail Core Sulfonamide Show Potent and Lasting Effects for Glaucoma Therapy
2024 Angeli A.; Chelli I.; Lucarini L.; Sgambellone S.; Marri S.; Villano S.; Ferraroni M.; De Luca V.; Capasso C.; Carta F.; Supuran C.T.
One-Pot Procedure for the Synthesis of Asymmetric Substituted Ureido Benzene Sulfonamides as Effective Inhibitors of Carbonic Anhydrase Enzymes
2021 Vannozzi G.; Vullo D.; Angeli A.; Ferraroni M.; Combs J.; Lomelino C.; Andring J.; Mckenna R.; Bartolucci G.; Pallecchi M.; Lucarini L.; Sgambellone S.; Masini E.; Carta F.; Supuran C.T.
Role of histamine H3 receptor antagonists on intraocular pressure reduction in rabbit models of transient ocular hypertension and glaucoma
2019 Lanzi C.; Lucarini L.; Durante M.; Sgambellone S.; Pini A.; Catarinicchia S.; Lazewska D.; Kiec-Kononowicz K.; Stark H.; Masini E.
Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action
2020 Bonardi A.; Nocentini A.; Bua S.; Combs J.; Lomelino C.; Andring J.; Lucarini L.; Sgambellone S.; Masini E.; McKenna R.; Gratteri P.; Supuran C.T.
The histamine h4 receptor participates in the anti-neuropathic effect of the adenosine a3 receptor agonist ib-meca: Role of cd4+ t cells
2021 Micheli L.; Durante M.; Lucarini E.; Sgambellone S.; Lucarini L.; Di Cesare Mannelli L.; Ghelardini C.; Masini E.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 2-(2-Hydroxyethyl)piperazine derivatives as potent human carbonic anhydrase inhibitors: Synthesis, enzyme inhibition, computational studies and antiglaucoma activity | 2022 | Chiaramonte N.; Angeli A.; Sgambellone S.; Bonardi A.; Nocentini A.; Bartolucci G.; Braconi L.; Dei S.; Lucarini L.; Teodori E.; Gratteri P.; Wunsch B.; Supuran C.T.; Romanelli M.N. | |
| Adenosine A3 Receptor (A3AR) Agonist for the Treatment of Bleomycin-Induced Lung Fibrosis in Mice | 2022 | Sgambellone, Silvia; Marri, Silvia; Catarinicchia, Stefano; Pini, Alessandro; Tosh, Dilip K.; Jacobson, Kenneth A.; Masini, Emanuela; Salvemini, Daniela; Lucarini, Laura | |
| CNS-Sparing Histamine H3 Receptor Antagonist as a Candidate to Prevent the Diabetes-Associated Gastrointestinal Symptoms | 2022 | Rosa, Arianna Carolina; Nardini, Patrizia; Sgambellone, Silvia; Gurrieri, Maura; Spampinato, Simona Federica; Dell'Accio, Alfonso; Chazot, Paul L; Obara, Ilona; Liu, Wai L; Pini, Alessandro | |
| D-Tagatose Feeding Reduces the Risk of Sugar-Induced Exacerbation of Myocardial I/R Injury When Compared to Its Isomer Fructose | 2021 | Mariaconcetta Durante, Silvia Sgambellone, Laura Lucarini, Paola Failli, Annunziatina Laurino, Debora Collotta, Gustavo Provensi, Emanuela Masini, Massimo Collino | |
| Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy | 2018 | Nocentini, Alessio; Ceruso, Mariangela; Bua, Silvia; Lomelino, Carrie L.; Andring, Jacob T.; McKenna, Robert; Lanzi, Cecilia; Sgambellone, Silvia; Pecori, Riccardo; Matucci, Rosanna; Filippi, Luca; Gratteri, Paola; Carta, Fabrizio; Masini, Emanuela; Selleri, Silvia*; Supuran, Claudiu T. | |
| Effects of new nsaid-cai hybrid compounds in inflammation and lung fibrosis | 2020 | Lucarini L.; Durante M.; Sgambellone S.; Lanzi C.; Bigagli E.; Akgul O.; Masini E.; Supuran C.T.; Carta F. | |
| Effects of PARP-1 deficiency and histamine H4receptor inhibition in an inflammatory model of lung fibrosis in mice | 2019 | Durante M.; Sgambellone S.; Lanzi C.; Nardini P.; Pini A.; Moroni F.; Masini E.; Lucarini L. | |
| Histamine H3 receptor (H3R) antagonist-Nitric Oxide (NO) donor hybrid compounds as a new therapeutic strategy for the treatment of glaucoma and retinal neuroprotection | 2023 | Sgambellone Silvia | |
| Identification of Bivalent Ligands with Melatonin Receptor Agonist and Fatty Acid Amide Hydrolase (FAAH) Inhibitory Activity That Exhibit Ocular Hypotensive Effect in the Rabbit | 2018 | Spadoni, Gilberto; Bedini, Annalida; Furiassi, Lucia; Mari, Michele; Mor, Marco; Scalvini, Laura; Lodola, Alessio; Ghidini, Andrea; Lucini, Valeria; Dugnani, Silvana; Scaglione, Francesco; Piomelli, Daniele; Jung, Kwang-Mook; Supuran, Claudiu T; Lucarini, Laura; Durante, Mariaconcetta; Sgambellone, Silvia; Masini, Emanuela; Rivara, Silvia | |
| NCX 470 Exerts Retinal Cell Protection and Enhances Ophthalmic Artery Blood Flow After Ischemia/Reperfusion Injury of Optic Nerve Head and Retina | 2023 | Sgambellone, Silvia; Marri, Silvia; Villano, Serafina; Masini, Emanuela; Provensi, Gustavo; Bastia, Elena; Galli, Corinna; Brambilla, Stefania; Impagnatiello, Francesco; Lucarini, Laura | |
| NCX 470 Restores Ocular Hemodynamics and Retinal Cell Physiology After ET-1-Induced Ischemia/Reperfusion Injury of Optic Nerve and Retina in Rabbits | 2022 | Elena Bastia; Silvia Sgambellone; Laura Lucarini; Gustavo Provensi; Stefania Brambilla; Corinna Galli; Nicoletta Almirante; Francesco Impagnatiello | |
| Novel Carbonic Anhydrase Inhibitors with Dual-Tail Core Sulfonamide Show Potent and Lasting Effects for Glaucoma Therapy | 2024 | Angeli A.; Chelli I.; Lucarini L.; Sgambellone S.; Marri S.; Villano S.; Ferraroni M.; De Luca V.; Capasso C.; Carta F.; Supuran C.T. | |
| One-Pot Procedure for the Synthesis of Asymmetric Substituted Ureido Benzene Sulfonamides as Effective Inhibitors of Carbonic Anhydrase Enzymes | 2021 | Vannozzi G.; Vullo D.; Angeli A.; Ferraroni M.; Combs J.; Lomelino C.; Andring J.; Mckenna R.; Bartolucci G.; Pallecchi M.; Lucarini L.; Sgambellone S.; Masini E.; Carta F.; Supuran C.T. | |
| Role of histamine H3 receptor antagonists on intraocular pressure reduction in rabbit models of transient ocular hypertension and glaucoma | 2019 | Lanzi C.; Lucarini L.; Durante M.; Sgambellone S.; Pini A.; Catarinicchia S.; Lazewska D.; Kiec-Kononowicz K.; Stark H.; Masini E. | |
| Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action | 2020 | Bonardi A.; Nocentini A.; Bua S.; Combs J.; Lomelino C.; Andring J.; Lucarini L.; Sgambellone S.; Masini E.; McKenna R.; Gratteri P.; Supuran C.T. | |
| The histamine h4 receptor participates in the anti-neuropathic effect of the adenosine a3 receptor agonist ib-meca: Role of cd4+ t cells | 2021 | Micheli L.; Durante M.; Lucarini E.; Sgambellone S.; Lucarini L.; Di Cesare Mannelli L.; Ghelardini C.; Masini E. |